Chlorine in PDB 4hzr: Crystal Structure of ACK1 Kinase Domain

All present enzymatic activity of Crystal Structure of ACK1 Kinase Domain:
2.7.10.2; 2.7.11.1;

The structure of Crystal Structure of ACK1 Kinase Domain, PDB code: 4hzr was solved by K.S.Gajiwala, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	38.43 / 1.31
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	71.057, 42.340, 92.590, 90.00, 98.60, 90.00
R / Rfree (%)	21 / 30.6

The binding sites of Chlorine atom in the Crystal Structure of ACK1 Kinase Domain (pdb code 4hzr). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of ACK1 Kinase Domain, PDB code: 4hzr:

Chlorine binding site 1 out of 1 in the Crystal Structure of ACK1 Kinase Domain


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of ACK1 Kinase Domain within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl403 b:63.8 occ:1.00 O B:HOH692 3.5 31.8 1.0 O B:ASN179 3.6 20.9 1.0 CE1 B:PHE248 3.7 18.2 1.0 CA B:ALA180 3.8 19.5 1.0 CZ B:PHE248 3.8 20.3 1.0 C B:ASN179 3.9 19.3 1.0 N B:ALA180 4.0 18.9 1.0 O B:HOH581 4.4 25.8 1.0 CB B:ASN179 4.5 20.4 1.0 O B:HOH619 4.5 27.9 1.0 CB B:ALA276 4.6 19.8 1.0 CB B:ALA180 4.6 20.0 1.0 CA B:ASN179 4.8 20.0 1.0 C B:ALA180 4.8 18.4 1.0 O B:HOH583 4.9 29.8 1.0 O B:ALA180 5.0 20.1 1.0

K.S.Gajiwala, K.Maegley, R.Ferre, Y.A.He, X.Yu. ACK1: Activation and Regulation By Allostery. Plos One V. 8 53994 2013.
ISSN: ESSN 1932-6203
PubMed: 23342057
DOI: 10.1371/JOURNAL.PONE.0053994