Chlorine »
PDB 4i22-4ibe »
4i9u »
Chlorine in PDB 4i9u: Crystal Structure of Rabbit Ldha in Complex with A Fragment Inhibitor AP26256
Enzymatic activity of Crystal Structure of Rabbit Ldha in Complex with A Fragment Inhibitor AP26256
All present enzymatic activity of Crystal Structure of Rabbit Ldha in Complex with A Fragment Inhibitor AP26256:
1.1.1.27;
1.1.1.27;
Protein crystallography data
The structure of Crystal Structure of Rabbit Ldha in Complex with A Fragment Inhibitor AP26256, PDB code: 4i9u
was solved by
T.Zhou,
A.Kohlmann,
Z.G.Stephan,
L.Commodore,
M.T.Greenfield,
X.Zhu,
D.C.Dalgarno,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 50.00 / 2.50 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 83.690, 138.740, 138.170, 90.00, 94.82, 90.00 |
| R / Rfree (%) | 22.2 / 27.3 |
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Rabbit Ldha in Complex with A Fragment Inhibitor AP26256
(pdb code 4i9u). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 8 binding sites of Chlorine where determined in the Crystal Structure of Rabbit Ldha in Complex with A Fragment Inhibitor AP26256, PDB code: 4i9u:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8;
In total 8 binding sites of Chlorine where determined in the Crystal Structure of Rabbit Ldha in Complex with A Fragment Inhibitor AP26256, PDB code: 4i9u:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8;
Chlorine binding site 1 out of 8 in 4i9u
Go back to
Chlorine Binding Sites List in 4i9u
Chlorine binding site 1 out
of 8 in the Crystal Structure of Rabbit Ldha in Complex with A Fragment Inhibitor AP26256
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Crystal Structure of Rabbit Ldha in Complex with A Fragment Inhibitor AP26256 within 5.0Å range:
|
Chlorine binding site 2 out of 8 in 4i9u
Go back to
Chlorine Binding Sites List in 4i9u
Chlorine binding site 2 out
of 8 in the Crystal Structure of Rabbit Ldha in Complex with A Fragment Inhibitor AP26256
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 2 of Crystal Structure of Rabbit Ldha in Complex with A Fragment Inhibitor AP26256 within 5.0Å range:
|
Chlorine binding site 3 out of 8 in 4i9u
Go back to
Chlorine Binding Sites List in 4i9u
Chlorine binding site 3 out
of 8 in the Crystal Structure of Rabbit Ldha in Complex with A Fragment Inhibitor AP26256
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 3 of Crystal Structure of Rabbit Ldha in Complex with A Fragment Inhibitor AP26256 within 5.0Å range:
|
Chlorine binding site 4 out of 8 in 4i9u
Go back to
Chlorine Binding Sites List in 4i9u
Chlorine binding site 4 out
of 8 in the Crystal Structure of Rabbit Ldha in Complex with A Fragment Inhibitor AP26256
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 4 of Crystal Structure of Rabbit Ldha in Complex with A Fragment Inhibitor AP26256 within 5.0Å range:
|
Chlorine binding site 5 out of 8 in 4i9u
Go back to
Chlorine Binding Sites List in 4i9u
Chlorine binding site 5 out
of 8 in the Crystal Structure of Rabbit Ldha in Complex with A Fragment Inhibitor AP26256
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 5 of Crystal Structure of Rabbit Ldha in Complex with A Fragment Inhibitor AP26256 within 5.0Å range:
|
Chlorine binding site 6 out of 8 in 4i9u
Go back to
Chlorine Binding Sites List in 4i9u
Chlorine binding site 6 out
of 8 in the Crystal Structure of Rabbit Ldha in Complex with A Fragment Inhibitor AP26256
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 6 of Crystal Structure of Rabbit Ldha in Complex with A Fragment Inhibitor AP26256 within 5.0Å range:
|
Chlorine binding site 7 out of 8 in 4i9u
Go back to
Chlorine Binding Sites List in 4i9u
Chlorine binding site 7 out
of 8 in the Crystal Structure of Rabbit Ldha in Complex with A Fragment Inhibitor AP26256
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 7 of Crystal Structure of Rabbit Ldha in Complex with A Fragment Inhibitor AP26256 within 5.0Å range:
|
Chlorine binding site 8 out of 8 in 4i9u
Go back to
Chlorine Binding Sites List in 4i9u
Chlorine binding site 8 out
of 8 in the Crystal Structure of Rabbit Ldha in Complex with A Fragment Inhibitor AP26256
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 8 of Crystal Structure of Rabbit Ldha in Complex with A Fragment Inhibitor AP26256 within 5.0Å range:
|
Reference:
A.Kohlmann,
S.G.Zech,
F.Li,
T.Zhou,
R.M.Squillace,
L.Commodore,
M.T.Greenfield,
X.Lu,
D.P.Miller,
W.S.Huang,
J.Qi,
R.M.Thomas,
Y.Wang,
S.Zhang,
R.Dodd,
S.Liu,
R.Xu,
Y.Xu,
J.J.Miret,
V.Rivera,
T.Clackson,
W.C.Shakespeare,
X.Zhu,
D.C.Dalgarno.
Fragment Growing and Linking Lead to Novel Nanomolar Lactate Dehydrogenase Inhibitors. J.Med.Chem. V. 56 1023 2013.
ISSN: ISSN 0022-2623
PubMed: 23302067
DOI: 10.1021/JM3014844
Page generated: Sun Jul 21 16:29:16 2024
ISSN: ISSN 0022-2623
PubMed: 23302067
DOI: 10.1021/JM3014844
Last articles
Zn in 9J0NZn in 9J0O
Zn in 9J0P
Zn in 9FJX
Zn in 9EKB
Zn in 9C0F
Zn in 9CAH
Zn in 9CH0
Zn in 9CH3
Zn in 9CH1
