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Atomistry » Chlorine » PDB 4io3-4ixt » 4io8 » |
Chlorine in PDB 4io8: Crystal Structure of Human HSP70 Complexed with 4-{(2R,3S,4R)-5-[(R)- 6-Amino-8-(3,4-Dichloro-Benzylamino)-Purin-9-Yl]-3,4-Dihydroxy- Tetrahydro-Furan-2-Ylmethoxymethyl}-BenzonitrileProtein crystallography data
The structure of Crystal Structure of Human HSP70 Complexed with 4-{(2R,3S,4R)-5-[(R)- 6-Amino-8-(3,4-Dichloro-Benzylamino)-Purin-9-Yl]-3,4-Dihydroxy- Tetrahydro-Furan-2-Ylmethoxymethyl}-Benzonitrile, PDB code: 4io8
was solved by
D.Musil,
S.Scholz,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Human HSP70 Complexed with 4-{(2R,3S,4R)-5-[(R)- 6-Amino-8-(3,4-Dichloro-Benzylamino)-Purin-9-Yl]-3,4-Dihydroxy- Tetrahydro-Furan-2-Ylmethoxymethyl}-Benzonitrile
(pdb code 4io8). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Human HSP70 Complexed with 4-{(2R,3S,4R)-5-[(R)- 6-Amino-8-(3,4-Dichloro-Benzylamino)-Purin-9-Yl]-3,4-Dihydroxy- Tetrahydro-Furan-2-Ylmethoxymethyl}-Benzonitrile, PDB code: 4io8: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 4io8Go back to Chlorine Binding Sites List in 4io8
Chlorine binding site 1 out
of 2 in the Crystal Structure of Human HSP70 Complexed with 4-{(2R,3S,4R)-5-[(R)- 6-Amino-8-(3,4-Dichloro-Benzylamino)-Purin-9-Yl]-3,4-Dihydroxy- Tetrahydro-Furan-2-Ylmethoxymethyl}-Benzonitrile
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 4io8Go back to Chlorine Binding Sites List in 4io8
Chlorine binding site 2 out
of 2 in the Crystal Structure of Human HSP70 Complexed with 4-{(2R,3S,4R)-5-[(R)- 6-Amino-8-(3,4-Dichloro-Benzylamino)-Purin-9-Yl]-3,4-Dihydroxy- Tetrahydro-Furan-2-Ylmethoxymethyl}-Benzonitrile
Mono view Stereo pair view
Reference:
R.Schlecht,
S.R.Scholz,
H.Dahmen,
A.Wegener,
C.Sirrenberg,
D.Musil,
J.Bomke,
H.M.Eggenweiler,
M.P.Mayer,
B.Bukau.
Functional Analysis of HSP70 Inhibitors. Plos One V. 8 78443 2013.
Page generated: Sat Dec 12 10:46:34 2020
ISSN: ESSN 1932-6203 PubMed: 24265689 DOI: 10.1371/JOURNAL.PONE.0078443 |
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