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Atomistry » Chlorine » PDB 4io3-4ixt » 4iq6 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 4io3-4ixt » 4iq6 » |
Chlorine in PDB 4iq6: Gsk-3BETA with Inhibitor 6-Chloro-N-Cyclohexyl-4-(1H-Pyrrolo[2,3- B]Pyridin-3-Yl)Pyridin-2-AmineEnzymatic activity of Gsk-3BETA with Inhibitor 6-Chloro-N-Cyclohexyl-4-(1H-Pyrrolo[2,3- B]Pyridin-3-Yl)Pyridin-2-Amine
All present enzymatic activity of Gsk-3BETA with Inhibitor 6-Chloro-N-Cyclohexyl-4-(1H-Pyrrolo[2,3- B]Pyridin-3-Yl)Pyridin-2-Amine:
2.7.11.1; 2.7.11.26; Protein crystallography data
The structure of Gsk-3BETA with Inhibitor 6-Chloro-N-Cyclohexyl-4-(1H-Pyrrolo[2,3- B]Pyridin-3-Yl)Pyridin-2-Amine, PDB code: 4iq6
was solved by
Y.Tong,
K.D.Stewart,
A.S.Florjancic,
J.E.Harlan,
P.J.Merta,
M.Przytulinska,
N.Soni,
K.S.Swinger,
H.Zhu,
E.F.Johnson,
A.R.Shoemaker,
T.D.Penning,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Gsk-3BETA with Inhibitor 6-Chloro-N-Cyclohexyl-4-(1H-Pyrrolo[2,3- B]Pyridin-3-Yl)Pyridin-2-Amine
(pdb code 4iq6). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Gsk-3BETA with Inhibitor 6-Chloro-N-Cyclohexyl-4-(1H-Pyrrolo[2,3- B]Pyridin-3-Yl)Pyridin-2-Amine, PDB code: 4iq6: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 4iq6Go back to Chlorine Binding Sites List in 4iq6
Chlorine binding site 1 out
of 2 in the Gsk-3BETA with Inhibitor 6-Chloro-N-Cyclohexyl-4-(1H-Pyrrolo[2,3- B]Pyridin-3-Yl)Pyridin-2-Amine
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 4iq6Go back to Chlorine Binding Sites List in 4iq6
Chlorine binding site 2 out
of 2 in the Gsk-3BETA with Inhibitor 6-Chloro-N-Cyclohexyl-4-(1H-Pyrrolo[2,3- B]Pyridin-3-Yl)Pyridin-2-Amine
Mono view Stereo pair view
Reference:
Y.Tong,
K.D.Stewart,
A.S.Florjancic,
J.E.Harlan,
P.J.Merta,
M.Przytulinska,
N.Soni,
K.K.Swinger,
H.Zhu,
E.F.Johnson,
A.R.Shoemaker,
T.D.Penning.
Azaindole-Based Inhibitors of CDC7 Kinase: Impact of the Pre-Dfg Residue, Val 195. Acs Med Chem Lett V. 4 211 2013.
Page generated: Sat Dec 12 10:46:39 2020
ISSN: ISSN 1948-5875 PubMed: 24900653 DOI: 10.1021/ML300348C |
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