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Atomistry » Chlorine » PDB 4ixu-4j7v » 4j5j | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 4ixu-4j7v » 4j5j » |
Chlorine in PDB 4j5j: Crystal Structure of Multidrug Resistant Hiv-1 Protease Clinical Isolate PR20 in Complex with AmprenavirEnzymatic activity of Crystal Structure of Multidrug Resistant Hiv-1 Protease Clinical Isolate PR20 in Complex with Amprenavir
All present enzymatic activity of Crystal Structure of Multidrug Resistant Hiv-1 Protease Clinical Isolate PR20 in Complex with Amprenavir:
3.4.23.16; Protein crystallography data
The structure of Crystal Structure of Multidrug Resistant Hiv-1 Protease Clinical Isolate PR20 in Complex with Amprenavir, PDB code: 4j5j
was solved by
C.H.Shen,
I.T.Weber,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Multidrug Resistant Hiv-1 Protease Clinical Isolate PR20 in Complex with Amprenavir
(pdb code 4j5j). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Crystal Structure of Multidrug Resistant Hiv-1 Protease Clinical Isolate PR20 in Complex with Amprenavir, PDB code: 4j5j: Jump to Chlorine binding site number: 1; 2; 3; Chlorine binding site 1 out of 3 in 4j5jGo back to Chlorine Binding Sites List in 4j5j
Chlorine binding site 1 out
of 3 in the Crystal Structure of Multidrug Resistant Hiv-1 Protease Clinical Isolate PR20 in Complex with Amprenavir
Mono view Stereo pair view
Chlorine binding site 2 out of 3 in 4j5jGo back to Chlorine Binding Sites List in 4j5j
Chlorine binding site 2 out
of 3 in the Crystal Structure of Multidrug Resistant Hiv-1 Protease Clinical Isolate PR20 in Complex with Amprenavir
Mono view Stereo pair view
Chlorine binding site 3 out of 3 in 4j5jGo back to Chlorine Binding Sites List in 4j5j
Chlorine binding site 3 out
of 3 in the Crystal Structure of Multidrug Resistant Hiv-1 Protease Clinical Isolate PR20 in Complex with Amprenavir
Mono view Stereo pair view
Reference:
J.Agniswamy,
C.H.Shen,
Y.F.Wang,
A.K.Ghosh,
K.V.Rao,
C.X.Xu,
J.M.Sayer,
J.M.Louis,
I.T.Weber.
Extreme Multidrug Resistant Hiv-1 Protease with 20 Mutations Is Resistant to Novel Protease Inhibitors with P1'-Pyrrolidinone or P2-Tris-Tetrahydrofuran. J.Med.Chem. V. 56 4017 2013.
Page generated: Sat Dec 12 10:47:35 2020
ISSN: ISSN 0022-2623 PubMed: 23590295 DOI: 10.1021/JM400231V |
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