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Atomistry » Chlorine » PDB 4j8p-4jk8 » 4jk5 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 4j8p-4jk8 » 4jk5 » |
Chlorine in PDB 4jk5: Human Urokinase-Type Plasminogen Activator (Upa) in Complex with A Bicyclic Peptide Inhibitor (UK18-D-Ser)Enzymatic activity of Human Urokinase-Type Plasminogen Activator (Upa) in Complex with A Bicyclic Peptide Inhibitor (UK18-D-Ser)
All present enzymatic activity of Human Urokinase-Type Plasminogen Activator (Upa) in Complex with A Bicyclic Peptide Inhibitor (UK18-D-Ser):
3.4.21.73; Protein crystallography data
The structure of Human Urokinase-Type Plasminogen Activator (Upa) in Complex with A Bicyclic Peptide Inhibitor (UK18-D-Ser), PDB code: 4jk5
was solved by
S.A.Buth,
P.G.Leiman,
S.Chen,
C.Heinis,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Human Urokinase-Type Plasminogen Activator (Upa) in Complex with A Bicyclic Peptide Inhibitor (UK18-D-Ser)
(pdb code 4jk5). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Human Urokinase-Type Plasminogen Activator (Upa) in Complex with A Bicyclic Peptide Inhibitor (UK18-D-Ser), PDB code: 4jk5: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 4jk5Go back to Chlorine Binding Sites List in 4jk5
Chlorine binding site 1 out
of 2 in the Human Urokinase-Type Plasminogen Activator (Upa) in Complex with A Bicyclic Peptide Inhibitor (UK18-D-Ser)
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 4jk5Go back to Chlorine Binding Sites List in 4jk5
Chlorine binding site 2 out
of 2 in the Human Urokinase-Type Plasminogen Activator (Upa) in Complex with A Bicyclic Peptide Inhibitor (UK18-D-Ser)
Mono view Stereo pair view
Reference:
S.Chen,
D.Gfeller,
S.A.Buth,
O.Michielin,
P.G.Leiman,
C.Heinis.
Improving Binding Affinity and Stability of Peptide Ligands By Substituting Glycines with D-Amino Acids. Chembiochem V. 14 1316 2013.
Page generated: Sun Jul 21 17:29:24 2024
ISSN: ISSN 1439-4227 PubMed: 23828687 DOI: 10.1002/CBIC.201300228 |
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