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Atomistry » Chlorine » PDB 4jk9-4jtg » 4jlh | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 4jk9-4jtg » 4jlh » |
Chlorine in PDB 4jlh: Hiv-1 Integrase Catalytic Core Domain A128T Mutant Complexed with Allosteric InhibitorProtein crystallography data
The structure of Hiv-1 Integrase Catalytic Core Domain A128T Mutant Complexed with Allosteric Inhibitor, PDB code: 4jlh
was solved by
L.Feng,
M.Kvaratskhelia,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4jlh:
The structure of Hiv-1 Integrase Catalytic Core Domain A128T Mutant Complexed with Allosteric Inhibitor also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Hiv-1 Integrase Catalytic Core Domain A128T Mutant Complexed with Allosteric Inhibitor
(pdb code 4jlh). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Hiv-1 Integrase Catalytic Core Domain A128T Mutant Complexed with Allosteric Inhibitor, PDB code: 4jlh: Chlorine binding site 1 out of 1 in 4jlhGo back to Chlorine Binding Sites List in 4jlh
Chlorine binding site 1 out
of 1 in the Hiv-1 Integrase Catalytic Core Domain A128T Mutant Complexed with Allosteric Inhibitor
Mono view Stereo pair view
Reference:
L.Feng,
A.Sharma,
A.Slaughter,
N.Jena,
Y.Koh,
N.Shkriabai,
R.C.Larue,
P.A.Patel,
H.Mitsuya,
J.J.Kessl,
A.Engelman,
J.R.Fuchs,
M.Kvaratskhelia.
The A128T Resistance Mutation Reveals Aberrant Protein Multimerization As the Primary Mechanism of Action of Allosteric Hiv-1 Integrase Inhibitors. J.Biol.Chem. V. 288 15813 2013.
Page generated: Sat Dec 12 10:48:26 2020
ISSN: ISSN 0021-9258 PubMed: 23615903 DOI: 10.1074/JBC.M112.443390 |
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