Chlorine in PDB 4jx4: Structure of the Carboxyl Transferase Domain From Rhizobium Etli Pyruvate Carboxylase

All present enzymatic activity of Structure of the Carboxyl Transferase Domain From Rhizobium Etli Pyruvate Carboxylase:
6.4.1.1;

The structure of Structure of the Carboxyl Transferase Domain From Rhizobium Etli Pyruvate Carboxylase, PDB code: 4jx4 was solved by A.D.Lietzan, M.St Maurice, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.98
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	86.211, 157.227, 245.144, 90.00, 90.00, 90.00
R / Rfree (%)	21.4 / 24.8

The structure of Structure of the Carboxyl Transferase Domain From Rhizobium Etli Pyruvate Carboxylase also contains other interesting chemical elements:

Zinc

(Zn)

4 atoms

The binding sites of Chlorine atom in the Structure of the Carboxyl Transferase Domain From Rhizobium Etli Pyruvate Carboxylase (pdb code 4jx4). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structure of the Carboxyl Transferase Domain From Rhizobium Etli Pyruvate Carboxylase, PDB code: 4jx4:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Structure of the Carboxyl Transferase Domain From Rhizobium Etli Pyruvate Carboxylase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of the Carboxyl Transferase Domain From Rhizobium Etli Pyruvate Carboxylase within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1102 b:77.4 occ:1.00 N A:LYS989 3.2 60.8 1.0 N A:VAL990 3.2 54.4 1.0 C A:TYR987 3.3 61.2 1.0 CA A:TYR987 3.4 61.3 1.0 O A:TYR987 3.6 59.5 1.0 CB A:LYS989 3.7 62.5 1.0 CB A:TYR987 3.7 59.1 1.0 N A:PRO988 3.7 60.3 1.0 CA A:LYS989 3.7 59.6 1.0 CG2 A:VAL990 3.8 48.3 1.0 CD1 A:TYR987 3.8 58.2 1.0 CD A:PRO988 3.9 57.8 1.0 C A:LYS989 4.0 56.6 1.0 CB A:VAL990 4.1 49.5 1.0 C A:PRO988 4.1 62.6 1.0 CA A:VAL990 4.2 52.6 1.0 CG A:TYR987 4.3 57.9 1.0 CG A:PRO988 4.3 59.2 1.0 CE1 A:TYR628 4.4 75.4 1.0 CA A:PRO988 4.4 61.4 1.0 N A:TYR987 4.8 63.2 1.0 OH A:TYR628 4.9 74.1 1.0 CZ A:TYR628 4.9 74.7 1.0 CB A:PRO988 5.0 60.8 1.0 CG A:LYS989 5.0 67.4 1.0 CE1 A:TYR987 5.0 58.5 1.0 CD1 A:TYR628 5.0 73.7 1.0

Chlorine binding site 2 out of 2 in the Structure of the Carboxyl Transferase Domain From Rhizobium Etli Pyruvate Carboxylase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of the Carboxyl Transferase Domain From Rhizobium Etli Pyruvate Carboxylase within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl1102 b:86.8 occ:1.00 N C:VAL990 2.9 0.3 1.0 N C:LYS989 3.0 0.8 1.0 C C:TYR987 3.3 1.0 1.0 CB C:LYS989 3.4 0.9 1.0 CA C:LYS989 3.4 0.9 1.0 O C:TYR987 3.5 0.4 1.0 CA C:TYR987 3.6 0.4 1.0 CG2 C:VAL990 3.6 0.3 1.0 C C:LYS989 3.6 0.7 1.0 N C:PRO988 3.7 0.6 1.0 CB C:TYR987 3.8 0.1 1.0 CB C:VAL990 3.9 0.7 1.0 C C:PRO988 3.9 0.9 1.0 CA C:VAL990 4.0 0.0 1.0 CD C:PRO988 4.0 0.6 1.0 CD1 C:TYR987 4.1 0.3 1.0 CG C:PRO988 4.3 0.9 1.0 CA C:PRO988 4.4 0.7 1.0 CG C:TYR987 4.5 0.8 1.0 CE1 C:TYR628 4.7 0.3 1.0 O C:LYS989 4.8 0.2 1.0 O C:PRO988 4.9 0.2 1.0 CB C:PRO988 5.0 0.4 1.0 N C:TYR987 5.0 0.3 1.0

A.D.Lietzan, M.St Maurice. A Substrate-Induced Biotin Binding Pocket in the Carboxyltransferase Domain of Pyruvate Carboxylase. J.Biol.Chem. V. 288 19915 2013.
ISSN: ISSN 0021-9258
PubMed: 23698000
DOI: 10.1074/JBC.M113.477828