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Atomistry » Chlorine » PDB 4kbb-4kmx » 4km0 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 4kbb-4kmx » 4km0 » |
Chlorine in PDB 4km0: Crystal Structure of Dihydrofolate Reductase From Mycobacterium Tuberculosis in Complex with PyrimethamineEnzymatic activity of Crystal Structure of Dihydrofolate Reductase From Mycobacterium Tuberculosis in Complex with Pyrimethamine
All present enzymatic activity of Crystal Structure of Dihydrofolate Reductase From Mycobacterium Tuberculosis in Complex with Pyrimethamine:
1.5.1.3; Protein crystallography data
The structure of Crystal Structure of Dihydrofolate Reductase From Mycobacterium Tuberculosis in Complex with Pyrimethamine, PDB code: 4km0
was solved by
M.V.B Dias,
P.Tyrakis,
T.L.Blundell,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Dihydrofolate Reductase From Mycobacterium Tuberculosis in Complex with Pyrimethamine
(pdb code 4km0). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Dihydrofolate Reductase From Mycobacterium Tuberculosis in Complex with Pyrimethamine, PDB code: 4km0: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 4km0Go back to Chlorine Binding Sites List in 4km0
Chlorine binding site 1 out
of 2 in the Crystal Structure of Dihydrofolate Reductase From Mycobacterium Tuberculosis in Complex with Pyrimethamine
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 4km0Go back to Chlorine Binding Sites List in 4km0
Chlorine binding site 2 out
of 2 in the Crystal Structure of Dihydrofolate Reductase From Mycobacterium Tuberculosis in Complex with Pyrimethamine
Mono view Stereo pair view
Reference:
M.V.Dias,
P.Tyrakis,
R.R.Domingues,
A.F.Paes Leme,
T.L.Blundell.
Mycobacterium Tuberculosis Dihydrofolate Reductase Reveals Two Conformational States and A Possible Low Affinity Mechanism to Antifolate Drugs. Structure V. 22 94 2014.
Page generated: Sat Dec 12 10:50:41 2020
ISSN: ISSN 0969-2126 PubMed: 24210757 DOI: 10.1016/J.STR.2013.09.022 |
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