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Atomistry » Chlorine » PDB 4kmz-4kws » 4kne » |
Chlorine in PDB 4kne: Crystal Structure of Dihydrofolate Reductase From Mycobacterium Tuberculosis in Complex with CycloguanilEnzymatic activity of Crystal Structure of Dihydrofolate Reductase From Mycobacterium Tuberculosis in Complex with Cycloguanil
All present enzymatic activity of Crystal Structure of Dihydrofolate Reductase From Mycobacterium Tuberculosis in Complex with Cycloguanil:
1.5.1.3; Protein crystallography data
The structure of Crystal Structure of Dihydrofolate Reductase From Mycobacterium Tuberculosis in Complex with Cycloguanil, PDB code: 4kne
was solved by
M.V.B Dias,
P.Tyrakis,
T.L.Blundell,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Dihydrofolate Reductase From Mycobacterium Tuberculosis in Complex with Cycloguanil
(pdb code 4kne). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Dihydrofolate Reductase From Mycobacterium Tuberculosis in Complex with Cycloguanil, PDB code: 4kne: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 4kneGo back to Chlorine Binding Sites List in 4kne
Chlorine binding site 1 out
of 2 in the Crystal Structure of Dihydrofolate Reductase From Mycobacterium Tuberculosis in Complex with Cycloguanil
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 4kneGo back to Chlorine Binding Sites List in 4kne
Chlorine binding site 2 out
of 2 in the Crystal Structure of Dihydrofolate Reductase From Mycobacterium Tuberculosis in Complex with Cycloguanil
Mono view Stereo pair view
Reference:
M.V.Dias,
P.Tyrakis,
R.R.Domingues,
A.F.Paes Leme,
T.L.Blundell.
Mycobacterium Tuberculosis Dihydrofolate Reductase Reveals Two Conformational States and A Possible Low Affinity Mechanism to Antifolate Drugs. Structure V. 22 94 2014.
Page generated: Sun Jul 21 18:18:18 2024
ISSN: ISSN 0969-2126 PubMed: 24210757 DOI: 10.1016/J.STR.2013.09.022 |
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