Chlorine in PDB 4kum: Structure of LSD1-Corest-Tetrahydrofolate Complex

The structure of Structure of LSD1-Corest-Tetrahydrofolate Complex, PDB code: 4kum was solved by Z.Luka, S.Pakhomova, L.V.Loukachevitch, M.W.Calcutt, M.E.Newcomer, C.Wagner, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	40.00 / 3.05
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	123.864, 179.371, 235.054, 90.00, 90.00, 90.00
R / Rfree (%)	19.6 / 21.7

The binding sites of Chlorine atom in the Structure of LSD1-Corest-Tetrahydrofolate Complex (pdb code 4kum). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Structure of LSD1-Corest-Tetrahydrofolate Complex, PDB code: 4kum:

Chlorine binding site 1 out of 1 in the Structure of LSD1-Corest-Tetrahydrofolate Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of LSD1-Corest-Tetrahydrofolate Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl904 b:71.9 occ:1.00 NH1 A:ARG310 3.4 58.3 1.0 NE A:ARG312 3.4 62.7 1.0 CD A:ARG312 4.0 65.1 1.0 OD1 A:ASP311 4.4 96.0 1.0 CZ A:ARG312 4.4 63.8 1.0 NH2 A:ARG312 4.5 65.5 1.0 CZ A:ARG310 4.7 58.9 1.0 CG A:ARG312 4.7 65.7 1.0 CG A:ARG310 4.7 63.2 1.0 CD A:ARG310 4.8 62.9 1.0 CB A:ARG310 5.0 64.2 1.0

Z.Luka, S.Pakhomova, L.V.Loukachevitch, M.W.Calcutt, M.E.Newcomer, C.Wagner. Crystal Structure of the Histone Lysine Specific Demethylase LSD1 Complexed with Tetrahydrofolate. Protein Sci. V. 23 993 2014.
ISSN: ISSN 0961-8368
PubMed: 24715612
DOI: 10.1002/PRO.2469