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Atomistry » Chlorine » PDB 4lhj-4lqm » 4lng | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 4lhj-4lqm » 4lng » |
Chlorine in PDB 4lng: Aspergillus Fumigatus Protein Farnesyltransferase Complex with Farnesyldiphosphate and TipifarnibEnzymatic activity of Aspergillus Fumigatus Protein Farnesyltransferase Complex with Farnesyldiphosphate and Tipifarnib
All present enzymatic activity of Aspergillus Fumigatus Protein Farnesyltransferase Complex with Farnesyldiphosphate and Tipifarnib:
2.5.1.58; Protein crystallography data
The structure of Aspergillus Fumigatus Protein Farnesyltransferase Complex with Farnesyldiphosphate and Tipifarnib, PDB code: 4lng
was solved by
M.F.Mabanglo,
M.A.Hast,
L.S.Beese,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4lng:
The structure of Aspergillus Fumigatus Protein Farnesyltransferase Complex with Farnesyldiphosphate and Tipifarnib also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Aspergillus Fumigatus Protein Farnesyltransferase Complex with Farnesyldiphosphate and Tipifarnib
(pdb code 4lng). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Aspergillus Fumigatus Protein Farnesyltransferase Complex with Farnesyldiphosphate and Tipifarnib, PDB code: 4lng: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 4lngGo back to![]() ![]()
Chlorine binding site 1 out
of 2 in the Aspergillus Fumigatus Protein Farnesyltransferase Complex with Farnesyldiphosphate and Tipifarnib
![]() Mono view ![]() Stereo pair view
Chlorine binding site 2 out of 2 in 4lngGo back to![]() ![]()
Chlorine binding site 2 out
of 2 in the Aspergillus Fumigatus Protein Farnesyltransferase Complex with Farnesyldiphosphate and Tipifarnib
![]() Mono view ![]() Stereo pair view
Reference:
M.F.Mabanglo,
M.A.Hast,
N.B.Lubock,
H.W.Hellinga,
L.S.Beese.
Crystal Structures of the Fungal Pathogen Aspergillus Fumigatus Protein Farnesyltransferase Complexed with Substrates and Inhibitors Reveal Features For Antifungal Drug Design. Protein Sci. V. 23 289 2014.
Page generated: Sat Dec 12 10:53:14 2020
ISSN: ISSN 0961-8368 PubMed: 24347326 DOI: 10.1002/PRO.2411 |
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