Atomistry » Chlorine » PDB 4lhu-4lqx » 4lpm
Atomistry »
  Chlorine »
    PDB 4lhu-4lqx »
      4lpm »

Chlorine in PDB 4lpm: Frog M-Ferritin with Magnesium, D127E Mutant

Enzymatic activity of Frog M-Ferritin with Magnesium, D127E Mutant

All present enzymatic activity of Frog M-Ferritin with Magnesium, D127E Mutant:
1.16.3.1;

Protein crystallography data

The structure of Frog M-Ferritin with Magnesium, D127E Mutant, PDB code: 4lpm was solved by R.Torres, R.Behera, C.W.Goulding, E.C.Theil, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 45.98 / 1.65
Space group F 4 3 2
Cell size a, b, c (Å), α, β, γ (°) 183.913, 183.913, 183.913, 90.00, 90.00, 90.00
R / Rfree (%) 12.6 / 16.4

Other elements in 4lpm:

The structure of Frog M-Ferritin with Magnesium, D127E Mutant also contains other interesting chemical elements:

Magnesium (Mg) 11 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Frog M-Ferritin with Magnesium, D127E Mutant (pdb code 4lpm). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 6 binding sites of Chlorine where determined in the Frog M-Ferritin with Magnesium, D127E Mutant, PDB code: 4lpm:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6;

Chlorine binding site 1 out of 6 in 4lpm

Go back to Chlorine Binding Sites List in 4lpm
Chlorine binding site 1 out of 6 in the Frog M-Ferritin with Magnesium, D127E Mutant


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Frog M-Ferritin with Magnesium, D127E Mutant within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl201

b:11.2
occ:0.25
 HE2 A:HIS169 2.4 17.1 1.0
NE2 A:HIS169 3.2 14.3 1.0
HD22 A:LEU165 3.4 18.4 1.0
HD21 A:LEU165 3.7 18.4 1.0
HE1 A:HIS169 3.8 20.8 1.0
CE1 A:HIS169 3.9 17.3 1.0
CD2 A:LEU165 3.9 15.3 1.0
HD23 A:LEU165 4.1 18.4 1.0
CD2 A:HIS169 4.3 12.7 1.0
HD2 A:HIS169 4.5 15.2 1.0
CL A:CL203 4.8 22.1 0.2

Chlorine binding site 2 out of 6 in 4lpm

Go back to Chlorine Binding Sites List in 4lpm
Chlorine binding site 2 out of 6 in the Frog M-Ferritin with Magnesium, D127E Mutant


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Frog M-Ferritin with Magnesium, D127E Mutant within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl203

b:22.1
occ:0.25
 HE1 A:HIS169 2.8 20.8 1.0
CE1 A:HIS169 3.7 17.3 1.0
HE2 A:HIS169 4.5 17.1 1.0
NE2 A:HIS169 4.5 14.3 1.0
ND1 A:HIS169 4.6 16.8 1.0
HD1 A:HIS169 4.6 20.2 1.0
CL A:CL201 4.8 11.2 0.2

Chlorine binding site 3 out of 6 in 4lpm

Go back to Chlorine Binding Sites List in 4lpm
Chlorine binding site 3 out of 6 in the Frog M-Ferritin with Magnesium, D127E Mutant


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Frog M-Ferritin with Magnesium, D127E Mutant within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl206

b:29.0
occ:1.00
 H A:SER10 2.3 12.8 1.0
HA A:HIS9 2.9 12.6 1.0
O A:HOH492 3.1 38.8 1.0
O A:HOH441 3.1 33.0 1.0
N A:SER10 3.1 10.7 1.0
HB2 A:SER10 3.3 15.5 1.0
HB3 A:SER10 3.5 15.5 1.0
O A:HOH514 3.6 29.9 1.0
CB A:SER10 3.7 12.9 1.0
CA A:HIS9 3.8 10.5 1.0
CD2 A:HIS9 3.8 15.5 1.0
CG A:HIS9 3.8 13.5 1.0
C A:HIS9 3.9 10.2 1.0
NE2 A:HIS9 3.9 16.0 1.0
ND1 A:HIS9 4.0 13.1 1.0
CA A:SER10 4.0 10.4 1.0
CE1 A:HIS9 4.1 15.4 1.0
HD2 A:HIS9 4.1 18.6 1.0
HE2 A:HIS9 4.3 19.1 1.0
O A:TYR8 4.4 10.9 1.0
HD1 A:HIS9 4.4 15.8 1.0
CB A:HIS9 4.4 12.1 1.0
HH11 A:ARG5 4.5 14.6 1.0
HA A:SER10 4.5 12.5 1.0
HE1 A:HIS9 4.5 18.5 1.0
H A:ASP11 4.7 12.4 1.0
O A:HOH425 4.8 31.4 1.0
N A:HIS9 4.9 10.2 1.0
O A:HOH501 4.9 34.1 1.0
HB2 A:HIS9 4.9 14.6 1.0
NH1 A:ARG5 5.0 12.2 1.0

Chlorine binding site 4 out of 6 in 4lpm

Go back to Chlorine Binding Sites List in 4lpm
Chlorine binding site 4 out of 6 in the Frog M-Ferritin with Magnesium, D127E Mutant


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Frog M-Ferritin with Magnesium, D127E Mutant within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl207

b:18.8
occ:1.00
 H A:TYR8 2.4 11.7 1.0
O A:HOH462 2.8 39.2 1.0
HG2 A:ARG5 2.8 12.6 1.0
HE A:ARG5 3.0 13.2 1.0
H A:ASN7 3.1 12.3 1.0
HD3 A:ARG5 3.1 13.4 1.0
O A:HOH514 3.2 29.9 1.0
N A:TYR8 3.3 9.8 1.0
N A:ASN7 3.4 10.3 1.0
O A:TYR8 3.5 10.9 1.0
CD A:ARG5 3.6 11.2 1.0
HA A:GLN6 3.6 12.0 1.0
CG A:ARG5 3.6 10.5 1.0
NE A:ARG5 3.6 11.0 1.0
HB3 A:TYR8 3.9 10.8 1.0
O A:HOH397 3.9 22.4 1.0
C A:GLN6 4.0 9.2 1.0
HA A:ASN7 4.0 11.7 1.0
C A:TYR8 4.1 9.4 1.0
CA A:GLN6 4.1 10.0 1.0
N A:GLN6 4.1 10.0 1.0
CA A:TYR8 4.1 9.2 1.0
CA A:ASN7 4.1 9.8 1.0
C A:ASN7 4.2 9.2 1.0
HB3 A:ARG5 4.2 12.8 1.0
HG3 A:ARG5 4.3 12.6 1.0
H A:GLN6 4.3 12.0 1.0
C A:ARG5 4.4 9.8 1.0
CB A:TYR8 4.4 9.0 1.0
CB A:ARG5 4.5 10.7 1.0
HD2 A:ARG5 4.5 13.4 1.0
O A:HOH455 4.6 36.5 1.0
O A:ARG5 4.6 10.5 1.0
HB2 A:TYR8 4.6 10.8 1.0
O A:GLN6 4.8 10.3 1.0
HH11 A:ARG5 4.8 14.6 1.0
CZ A:ARG5 4.8 10.6 1.0
HA A:TYR8 5.0 11.1 1.0

Chlorine binding site 5 out of 6 in 4lpm

Go back to Chlorine Binding Sites List in 4lpm
Chlorine binding site 5 out of 6 in the Frog M-Ferritin with Magnesium, D127E Mutant


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Frog M-Ferritin with Magnesium, D127E Mutant within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl214

b:22.2
occ:0.33
 MG A:MG213 2.3 2.9 0.3
OE1 A:GLU127 3.4 16.8 1.0
O A:HOH529 3.4 37.3 1.0
HB2 A:SER131 3.7 21.3 1.0
HB3 A:SER131 3.8 21.3 1.0
O A:HOH396 3.8 23.9 1.0
O A:HOH583 3.9 51.2 1.0
CB A:SER131 4.2 17.8 1.0
O A:HOH489 4.4 34.4 1.0
CD A:GLU127 4.6 14.1 1.0
MG A:MG212 4.7 29.9 0.8
HA A:SER131 4.9 18.2 1.0

Chlorine binding site 6 out of 6 in 4lpm

Go back to Chlorine Binding Sites List in 4lpm
Chlorine binding site 6 out of 6 in the Frog M-Ferritin with Magnesium, D127E Mutant


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of Frog M-Ferritin with Magnesium, D127E Mutant within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl215

b:24.6
occ:1.00
 H A:ASP87 2.3 16.7 1.0
O A:HOH523 2.8 35.9 1.0
H A:GLU88 2.9 13.9 1.0
HG3 A:GLU88 3.0 25.1 1.0
O A:HOH591 3.1 39.4 1.0
N A:ASP87 3.1 13.9 1.0
HA A:ARG86 3.2 16.5 1.0
HB3 A:ARG86 3.3 16.3 1.0
HB2 A:ASP87 3.3 17.4 1.0
O A:HOH587 3.6 46.6 1.0
N A:GLU88 3.7 11.6 1.0
HG2 A:ARG86 3.8 17.9 1.0
CA A:ARG86 3.8 13.8 1.0
CB A:ARG86 3.9 13.6 1.0
HE A:ARG86 3.9 24.4 1.0
C A:ARG86 3.9 12.6 1.0
CA A:ASP87 4.0 13.5 1.0
CG A:GLU88 4.0 20.9 1.0
CB A:ASP87 4.0 14.4 1.0
O A:GLU88 4.1 13.7 1.0
HG2 A:GLU88 4.3 25.1 1.0
C A:ASP87 4.3 12.6 1.0
CG A:ARG86 4.3 14.9 1.0
OE2 A:GLU88 4.6 28.9 1.0
OD2 A:ASP87 4.6 22.2 1.0
CG A:ASP87 4.6 17.2 1.0
CA A:GLU88 4.6 13.2 1.0
O A:HOH589 4.7 41.6 1.0
NE A:ARG86 4.7 20.3 1.0
O A:HOH570 4.7 41.9 1.0
HB2 A:ARG86 4.8 16.3 1.0
CB A:GLU88 4.8 16.6 1.0
HB3 A:ASP87 4.8 17.4 1.0
CD A:GLU88 4.8 25.3 1.0
C A:GLU88 4.8 12.6 1.0
HA A:ASP87 4.8 16.2 1.0
HB3 A:GLU88 4.9 19.9 1.0

Reference:

R.Behera, R.Torres, T.Takehiko, J.Bradley, C.W.Goulding, E.C.Theil. D127E Ion Channel Exit Modification in Ferritin Nanocages Entraps Fe(II) and Impairs Its Distribution to Diiron Catalytic Centers To Be Published.
Page generated: Sun Jul 21 19:06:02 2024

Last articles

Zn in 2YRC
Zn in 2YQP
Zn in 2YR2
Zn in 2YQL
Zn in 2YPT
Zn in 2YPA
Zn in 2YPU
Zn in 2YNW
Zn in 2YNT
Zn in 2YNV
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy