Chlorine in PDB 4lsu: Crystal Structure of Broadly and Potently Neutralizing Antibody Vrc- PG20 in Complex with Hiv-1 Clade A/E 93TH057 GP120

The structure of Crystal Structure of Broadly and Potently Neutralizing Antibody Vrc- PG20 in Complex with Hiv-1 Clade A/E 93TH057 GP120, PDB code: 4lsu was solved by T.Zhou, S.Moquin, P.D.Kwong, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.14 / 2.30
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	164.283, 66.313, 95.108, 90.00, 108.34, 90.00
R / Rfree (%)	17.9 / 23.4

The binding sites of Chlorine atom in the Crystal Structure of Broadly and Potently Neutralizing Antibody Vrc- PG20 in Complex with Hiv-1 Clade A/E 93TH057 GP120 (pdb code 4lsu). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Broadly and Potently Neutralizing Antibody Vrc- PG20 in Complex with Hiv-1 Clade A/E 93TH057 GP120, PDB code: 4lsu:

Chlorine binding site 1 out of 1 in the Crystal Structure of Broadly and Potently Neutralizing Antibody Vrc- PG20 in Complex with Hiv-1 Clade A/E 93TH057 GP120


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Broadly and Potently Neutralizing Antibody Vrc- PG20 in Complex with Hiv-1 Clade A/E 93TH057 GP120 within 5.0Å range: probe atom residue distance (Å) B Occ H:Cl303 b:0.2 occ:1.00 O H:HOH466 2.2 0.1 1.0 NZ H:LYS210 3.0 72.6 1.0 CE H:LYS210 3.3 72.8 1.0 O H:HOH407 4.1 50.0 1.0 CG H:GLU212 4.2 91.1 1.0 O H:GLN192 4.5 72.1 1.0 OG1 H:THR193 4.7 54.3 1.0 CA H:GLY190 4.7 90.0 1.0 N H:GLY190 4.8 97.2 1.0 C H:GLY190 4.8 75.5 1.0 CD H:PRO213 4.8 87.5 1.0 CD H:LYS210 4.8 58.7 1.0 CA H:THR193 4.9 56.6 1.0 CB H:GLU212 4.9 81.9 1.0 C H:GLN192 5.0 78.0 1.0

T.Zhou, J.Zhu, X.Wu, S.Moquin, B.Zhang, P.Acharya, I.S.Georgiev, H.R.Altae-Tran, G.Y.Chuang, M.G.Joyce, Y.Do Kwon, N.S.Longo, M.K.Louder, T.Luongo, K.Mckee, C.A.Schramm, J.Skinner, Y.Yang, Z.Yang, Z.Zhang, A.Zheng, M.Bonsignori, B.F.Haynes, J.F.Scheid, M.C.Nussenzweig, M.Simek, D.R.Burton, W.C.Koff, J.C.Mullikin, M.Connors, L.Shapiro, G.J.Nabel, J.R.Mascola, P.D.Kwong. Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway For Hiv-1 Neutralization By VRC01-Class Antibodies. Immunity V. 39 245 2013.
ISSN: ISSN 1074-7613
PubMed: 23911655
DOI: 10.1016/J.IMMUNI.2013.04.012