Chlorine in PDB 4lwe: Crystal Structure of the Human HSP90-Alpha N-Domain Bound to the HSP90 Inhibitor FJ2

The structure of Crystal Structure of the Human HSP90-Alpha N-Domain Bound to the HSP90 Inhibitor FJ2, PDB code: 4lwe was solved by J.Li, F.Shi, B.Xiong, J.He, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	33.50 / 1.50
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	67.000, 90.366, 97.646, 90.00, 90.00, 90.00
R / Rfree (%)	18.7 / 19.5

The binding sites of Chlorine atom in the Crystal Structure of the Human HSP90-Alpha N-Domain Bound to the HSP90 Inhibitor FJ2 (pdb code 4lwe). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the Human HSP90-Alpha N-Domain Bound to the HSP90 Inhibitor FJ2, PDB code: 4lwe:

Chlorine binding site 1 out of 1 in the Crystal Structure of the Human HSP90-Alpha N-Domain Bound to the HSP90 Inhibitor FJ2


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Human HSP90-Alpha N-Domain Bound to the HSP90 Inhibitor FJ2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl301 b:14.8 occ:1.00 CL9 A:FJ2301 0.0 14.8 1.0 C06 A:FJ2301 1.7 13.5 1.0 C01 A:FJ2301 2.7 13.9 1.0 C05 A:FJ2301 2.7 13.7 1.0 O08 A:FJ2301 2.9 13.9 1.0 CD1 A:PHE138 3.3 12.7 1.0 ND2 A:ASN51 3.5 14.9 1.0 CG A:PHE138 3.9 11.4 1.0 CE1 A:PHE138 4.0 13.6 1.0 C02 A:FJ2301 4.0 13.0 1.0 C04 A:FJ2301 4.0 13.6 1.0 CB A:PHE138 4.0 13.2 1.0 CB A:ASN51 4.4 12.7 1.0 CG A:ASN51 4.4 13.3 1.0 C03 A:FJ2301 4.5 14.5 1.0 CE A:MET98 4.7 13.6 1.0 CD2 A:PHE138 4.9 12.1 1.0 CD2 A:LEU48 4.9 16.7 1.0 CG2 A:VAL186 4.9 14.9 1.0 CZ A:PHE138 5.0 14.1 1.0

J.Li, F.Shi, B.Xiong, J.He. Crystal Structure of the Human HSP90-Alpha N-Domain Bound to the HSP90 Inhibitor FJ2 To Be Published.