Chlorine in PDB 4ma8: Crystal Structure of Mouse Prion Protein Complexed with Chlorpromazine

The structure of Crystal Structure of Mouse Prion Protein Complexed with Chlorpromazine, PDB code: 4ma8 was solved by P.K.Baral, M.Swayampakula, M.N.G.James, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	34.99 / 2.20
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	83.262, 106.883, 75.594, 90.00, 95.32, 90.00
R / Rfree (%)	19.5 / 23.6

The binding sites of Chlorine atom in the Crystal Structure of Mouse Prion Protein Complexed with Chlorpromazine (pdb code 4ma8). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Mouse Prion Protein Complexed with Chlorpromazine, PDB code: 4ma8:

Chlorine binding site 1 out of 1 in the Crystal Structure of Mouse Prion Protein Complexed with Chlorpromazine


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Mouse Prion Protein Complexed with Chlorpromazine within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl301 b:0.6 occ:0.80 CL1 C:Z80301 0.0 0.6 0.8 C10 C:Z80301 1.7 0.1 0.8 C11 C:Z80301 2.6 0.4 0.8 C9 C:Z80301 2.7 0.9 0.8 CG2 C:ILE182 3.3 68.4 1.0 NE2 C:GLN186 3.3 85.2 1.0 CB C:GLN186 3.3 64.6 1.0 CG C:GLN186 3.7 70.4 1.0 O C:ILE182 3.7 56.1 1.0 C4 C:Z80301 3.9 1.0 0.8 C8 C:Z80301 3.9 0.8 0.8 CD C:GLN186 4.0 79.6 1.0 CA C:GLN186 4.3 62.2 1.0 C C:ILE182 4.4 55.2 1.0 C3 C:Z80301 4.4 0.7 0.8 N C:GLN186 4.5 59.1 1.0 CB C:ILE182 4.5 64.8 1.0 CG C:TYR162 4.6 65.5 1.0 CD1 C:TYR162 4.6 65.9 1.0 CB C:TYR162 4.7 63.0 1.0 CA C:ILE182 4.7 60.0 1.0 CD2 C:TYR128 4.8 96.0 1.0 N1 C:Z80301 5.0 0.7 0.8 C13 C:Z80301 5.0 0.3 0.8

P.K.Baral, M.Swayampakula, M.K.Rout, N.N.Kav, L.Spyracopoulos, A.Aguzzi, M.N.James. Structural Basis of Prion Inhibition By Phenothiazine Compounds. Structure V. 22 291 2014.
ISSN: ISSN 0969-2126
PubMed: 24373770
DOI: 10.1016/J.STR.2013.11.009