Atomistry » Chlorine » PDB 4mdk-4mkc » 4mfe
Atomistry »
  Chlorine »
    PDB 4mdk-4mkc »
      4mfe »

Chlorine in PDB 4mfe: Structure of the Carboxyl Transferase Domain From Rhizobium Etli Pyruvate Carboxylase with 3-Hydroxypyruvate

Enzymatic activity of Structure of the Carboxyl Transferase Domain From Rhizobium Etli Pyruvate Carboxylase with 3-Hydroxypyruvate

All present enzymatic activity of Structure of the Carboxyl Transferase Domain From Rhizobium Etli Pyruvate Carboxylase with 3-Hydroxypyruvate:
6.4.1.1;

Protein crystallography data

The structure of Structure of the Carboxyl Transferase Domain From Rhizobium Etli Pyruvate Carboxylase with 3-Hydroxypyruvate, PDB code: 4mfe was solved by A.D.Lietzan, M.St. Maurice, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 49.37 / 2.61
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 84.254, 157.849, 243.319, 90.00, 90.00, 90.00
R / Rfree (%) 17.7 / 22.5

Other elements in 4mfe:

The structure of Structure of the Carboxyl Transferase Domain From Rhizobium Etli Pyruvate Carboxylase with 3-Hydroxypyruvate also contains other interesting chemical elements:

Magnesium (Mg) 4 atoms
Zinc (Zn) 4 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Structure of the Carboxyl Transferase Domain From Rhizobium Etli Pyruvate Carboxylase with 3-Hydroxypyruvate (pdb code 4mfe). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Structure of the Carboxyl Transferase Domain From Rhizobium Etli Pyruvate Carboxylase with 3-Hydroxypyruvate, PDB code: 4mfe:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in 4mfe

Go back to Chlorine Binding Sites List in 4mfe
Chlorine binding site 1 out of 3 in the Structure of the Carboxyl Transferase Domain From Rhizobium Etli Pyruvate Carboxylase with 3-Hydroxypyruvate


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of the Carboxyl Transferase Domain From Rhizobium Etli Pyruvate Carboxylase with 3-Hydroxypyruvate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1105

b:61.1
occ:1.00
N A:LYS989 3.2 54.9 1.0
N A:VAL990 3.4 50.5 1.0
N A:PRO988 3.5 51.9 1.0
C A:TYR987 3.5 50.0 1.0
CA A:TYR987 3.6 48.1 1.0
CD A:PRO988 3.7 51.4 1.0
CB A:LYS989 3.8 63.6 1.0
CA A:LYS989 3.8 58.6 1.0
CB A:TYR987 4.1 47.2 1.0
C A:LYS989 4.1 55.1 1.0
CB A:VAL990 4.1 44.4 1.0
CD1 A:TYR987 4.1 45.4 1.0
C A:PRO988 4.1 54.0 1.0
CG2 A:VAL990 4.1 40.5 1.0
O A:TYR987 4.2 47.5 1.0
CG A:PRO988 4.3 53.0 1.0
CA A:PRO988 4.3 53.3 1.0
CA A:VAL990 4.3 44.9 1.0
CG A:TYR987 4.6 43.4 1.0
CB A:PRO988 4.8 54.7 1.0
N A:TYR987 4.9 48.8 1.0

Chlorine binding site 2 out of 3 in 4mfe

Go back to Chlorine Binding Sites List in 4mfe
Chlorine binding site 2 out of 3 in the Structure of the Carboxyl Transferase Domain From Rhizobium Etli Pyruvate Carboxylase with 3-Hydroxypyruvate


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of the Carboxyl Transferase Domain From Rhizobium Etli Pyruvate Carboxylase with 3-Hydroxypyruvate within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl1105

b:89.3
occ:1.00
N B:VAL990 3.1 0.1 1.0
N B:LYS989 3.1 0.8 1.0
C B:TYR987 3.4 0.1 1.0
N B:PRO988 3.5 0.4 1.0
CA B:TYR987 3.7 0.8 1.0
CA B:LYS989 3.7 0.3 1.0
O B:TYR987 3.7 0.4 1.0
CD B:PRO988 3.7 0.4 1.0
CB B:LYS989 3.8 0.0 1.0
C B:LYS989 3.8 1.0 1.0
C B:PRO988 4.0 0.9 1.0
CB B:TYR987 4.0 1.0 1.0
CB B:VAL990 4.0 98.2 1.0
CD1 B:TYR987 4.0 0.7 1.0
CA B:VAL990 4.1 1.0 1.0
CA B:PRO988 4.3 0.3 1.0
CG B:TYR987 4.5 0.5 1.0
CG B:PRO988 4.8 0.9 1.0
CB B:PRO988 4.9 0.6 1.0
O B:PRO988 5.0 0.2 1.0
O B:LYS989 5.0 0.0 1.0

Chlorine binding site 3 out of 3 in 4mfe

Go back to Chlorine Binding Sites List in 4mfe
Chlorine binding site 3 out of 3 in the Structure of the Carboxyl Transferase Domain From Rhizobium Etli Pyruvate Carboxylase with 3-Hydroxypyruvate


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Structure of the Carboxyl Transferase Domain From Rhizobium Etli Pyruvate Carboxylase with 3-Hydroxypyruvate within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl1105

b:80.9
occ:1.00
N C:LYS989 3.3 84.0 1.0
N C:VAL990 3.4 77.4 1.0
C C:TYR987 3.4 78.8 1.0
N C:PRO988 3.6 79.9 1.0
CA C:TYR987 3.6 78.3 1.0
CG2 C:VAL990 3.7 69.9 1.0
O C:TYR987 3.8 81.0 1.0
CD C:PRO988 3.9 81.7 1.0
CB C:LYS989 3.9 81.8 1.0
CA C:LYS989 3.9 82.5 1.0
CB C:VAL990 4.0 70.0 1.0
CB C:TYR987 4.0 74.7 1.0
CD1 C:TYR987 4.0 70.6 1.0
C C:LYS989 4.1 81.2 1.0
C C:PRO988 4.1 85.9 1.0
CA C:VAL990 4.3 72.5 1.0
CA C:PRO988 4.4 82.5 1.0
CG C:TYR987 4.5 72.2 1.0
CG C:PRO988 4.6 83.6 1.0
N C:TYR987 5.0 80.6 1.0

Reference:

A.D.Lietzan, M.St. Maurice. Insights Into the Carboxyltransferase Reaction of Pyruvate Carboxylase From the Structures of Bound Product and Intermediate Analogs. Biochem.Biophys.Res.Commun. V. 441 377 2013.
ISSN: ISSN 0006-291X
PubMed: 24157795
DOI: 10.1016/J.BBRC.2013.10.066
Page generated: Sat Dec 12 10:55:31 2020

Last articles

Zn in 7VD8
Zn in 7V1R
Zn in 7V1Q
Zn in 7VPF
Zn in 7T85
Zn in 7T5F
Zn in 7NF9
Zn in 7M4M
Zn in 7M4O
Zn in 7M4N
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy