Chlorine »
PDB 4mlb-4ms4 »
4mpx »
Chlorine in PDB 4mpx: Human Beta-Tryptase Co-Crystal Structure with [(1,1,3,3- Tetramethyldisiloxane-1,3-Diyl)Di-1-Benzothiene-4,2-Diyl]Bis({4-[3- (Aminomethyl)Phenyl]Piperidin-1-Yl}Methanone)
Enzymatic activity of Human Beta-Tryptase Co-Crystal Structure with [(1,1,3,3- Tetramethyldisiloxane-1,3-Diyl)Di-1-Benzothiene-4,2-Diyl]Bis({4-[3- (Aminomethyl)Phenyl]Piperidin-1-Yl}Methanone)
All present enzymatic activity of Human Beta-Tryptase Co-Crystal Structure with [(1,1,3,3- Tetramethyldisiloxane-1,3-Diyl)Di-1-Benzothiene-4,2-Diyl]Bis({4-[3- (Aminomethyl)Phenyl]Piperidin-1-Yl}Methanone):
3.4.21.59;
3.4.21.59;
Protein crystallography data
The structure of Human Beta-Tryptase Co-Crystal Structure with [(1,1,3,3- Tetramethyldisiloxane-1,3-Diyl)Di-1-Benzothiene-4,2-Diyl]Bis({4-[3- (Aminomethyl)Phenyl]Piperidin-1-Yl}Methanone), PDB code: 4mpx
was solved by
A.White,
A.J.Stein,
R.Suto,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 29.78 / 2.00 |
| Space group | P 31 2 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 78.310, 78.310, 165.722, 90.00, 90.00, 120.00 |
| R / Rfree (%) | 18.4 / 23.3 |
Other elements in 4mpx:
The structure of Human Beta-Tryptase Co-Crystal Structure with [(1,1,3,3- Tetramethyldisiloxane-1,3-Diyl)Di-1-Benzothiene-4,2-Diyl]Bis({4-[3- (Aminomethyl)Phenyl]Piperidin-1-Yl}Methanone) also contains other interesting chemical elements:
| Silicon | (Si) | 2 atoms |
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Human Beta-Tryptase Co-Crystal Structure with [(1,1,3,3- Tetramethyldisiloxane-1,3-Diyl)Di-1-Benzothiene-4,2-Diyl]Bis({4-[3- (Aminomethyl)Phenyl]Piperidin-1-Yl}Methanone)
(pdb code 4mpx). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Human Beta-Tryptase Co-Crystal Structure with [(1,1,3,3- Tetramethyldisiloxane-1,3-Diyl)Di-1-Benzothiene-4,2-Diyl]Bis({4-[3- (Aminomethyl)Phenyl]Piperidin-1-Yl}Methanone), PDB code: 4mpx:
Jump to Chlorine binding site number: 1; 2;
In total 2 binding sites of Chlorine where determined in the Human Beta-Tryptase Co-Crystal Structure with [(1,1,3,3- Tetramethyldisiloxane-1,3-Diyl)Di-1-Benzothiene-4,2-Diyl]Bis({4-[3- (Aminomethyl)Phenyl]Piperidin-1-Yl}Methanone), PDB code: 4mpx:
Jump to Chlorine binding site number: 1; 2;
Chlorine binding site 1 out of 2 in 4mpx
Go back to
Chlorine Binding Sites List in 4mpx
Chlorine binding site 1 out
of 2 in the Human Beta-Tryptase Co-Crystal Structure with [(1,1,3,3- Tetramethyldisiloxane-1,3-Diyl)Di-1-Benzothiene-4,2-Diyl]Bis({4-[3- (Aminomethyl)Phenyl]Piperidin-1-Yl}Methanone)
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Human Beta-Tryptase Co-Crystal Structure with [(1,1,3,3- Tetramethyldisiloxane-1,3-Diyl)Di-1-Benzothiene-4,2-Diyl]Bis({4-[3- (Aminomethyl)Phenyl]Piperidin-1-Yl}Methanone) within 5.0Å range:
|
Chlorine binding site 2 out of 2 in 4mpx
Go back to
Chlorine Binding Sites List in 4mpx
Chlorine binding site 2 out
of 2 in the Human Beta-Tryptase Co-Crystal Structure with [(1,1,3,3- Tetramethyldisiloxane-1,3-Diyl)Di-1-Benzothiene-4,2-Diyl]Bis({4-[3- (Aminomethyl)Phenyl]Piperidin-1-Yl}Methanone)
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 2 of Human Beta-Tryptase Co-Crystal Structure with [(1,1,3,3- Tetramethyldisiloxane-1,3-Diyl)Di-1-Benzothiene-4,2-Diyl]Bis({4-[3- (Aminomethyl)Phenyl]Piperidin-1-Yl}Methanone) within 5.0Å range:
|
Reference:
S.F.Giardina,
M.Pingle,
K.W.Foreman,
D.S.Werner,
D.E.Bergstrom,
F.Barany,
L.D.Arnold.
Target-Directed Self-Assembly of Homodimeric Drugs To Be Published.
Page generated: Sun Jul 21 20:06:58 2024
Last articles
Cl in 3T0WCl in 3SX4
Cl in 3T0L
Cl in 3T0M
Cl in 3SZ6
Cl in 3STG
Cl in 3SXS
Cl in 3SXR
Cl in 3SWW
Cl in 3SXQ
