Atomistry » Chlorine » PDB 4myo-4n96 » 4n4p
Atomistry »
  Chlorine »
    PDB 4myo-4n96 »
      4n4p »

Chlorine in PDB 4n4p: Crystal Structure of N-Acetylneuraminate Lyase From Mycoplasma Synoviae, Crystal Form I

Enzymatic activity of Crystal Structure of N-Acetylneuraminate Lyase From Mycoplasma Synoviae, Crystal Form I

All present enzymatic activity of Crystal Structure of N-Acetylneuraminate Lyase From Mycoplasma Synoviae, Crystal Form I:
4.1.3.3;

Protein crystallography data

The structure of Crystal Structure of N-Acetylneuraminate Lyase From Mycoplasma Synoviae, Crystal Form I, PDB code: 4n4p was solved by F.Georgescauld, K.Popova, A.J.Gupta, A.Bracher, J.R.Engen, M.Hayer-Hartl, F.U.Hartl, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 30.00 / 1.80
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 59.986, 136.350, 157.248, 90.00, 90.00, 90.00
R / Rfree (%) 17.3 / 20.7

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of N-Acetylneuraminate Lyase From Mycoplasma Synoviae, Crystal Form I (pdb code 4n4p). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 8 binding sites of Chlorine where determined in the Crystal Structure of N-Acetylneuraminate Lyase From Mycoplasma Synoviae, Crystal Form I, PDB code: 4n4p:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8;

Chlorine binding site 1 out of 8 in 4n4p

Go back to Chlorine Binding Sites List in 4n4p
Chlorine binding site 1 out of 8 in the Crystal Structure of N-Acetylneuraminate Lyase From Mycoplasma Synoviae, Crystal Form I


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of N-Acetylneuraminate Lyase From Mycoplasma Synoviae, Crystal Form I within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl300

b:18.8
occ:1.00
 O A:HOH469 3.0 20.4 1.0
OG1 A:THR51 3.1 9.7 1.0
N A:THR51 3.3 9.0 1.0
O A:HOH468 3.5 19.6 1.0
N A:SER50 3.5 10.3 1.0
CB A:ALA13 3.5 7.0 1.0
CB A:THR51 3.8 9.6 1.0
CB A:SER50 4.0 11.2 1.0
C A:GLY49 4.0 10.4 1.0
CA A:SER50 4.1 11.0 1.0
CE2 A:TYR46 4.2 11.2 1.0
CA A:THR51 4.2 9.2 1.0
C A:SER50 4.2 9.7 1.0
CA A:GLY49 4.2 9.9 1.0
NZ A:LYS167 4.4 14.1 1.0
CD2 A:TYR46 4.4 6.8 1.0
OG A:SER50 4.6 18.0 1.0
O A:HOH409 4.7 10.7 1.0
OH A:TYR139 4.8 14.4 1.0
CA A:ALA13 4.9 7.6 1.0
O A:GLY49 4.9 9.2 1.0
CE A:LYS167 4.9 13.7 1.0
O A:HOH460 5.0 18.9 1.0
O A:HOH687 5.0 40.9 1.0

Chlorine binding site 2 out of 8 in 4n4p

Go back to Chlorine Binding Sites List in 4n4p
Chlorine binding site 2 out of 8 in the Crystal Structure of N-Acetylneuraminate Lyase From Mycoplasma Synoviae, Crystal Form I


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of N-Acetylneuraminate Lyase From Mycoplasma Synoviae, Crystal Form I within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl301

b:22.1
occ:1.00
 O A:HOH424 2.8 13.0 1.0
O A:HOH518 3.1 25.4 1.0
N A:TYR278 3.2 15.3 1.0
O A:HOH413 3.3 11.2 1.0
CG A:GLN255 3.7 11.6 1.0
CD2 A:TYR278 3.8 14.5 1.0
CB A:GLN255 3.8 9.8 1.0
CB A:TYR278 3.8 15.8 1.0
CD A:ARG277 3.8 18.6 1.0
CA A:TYR278 4.0 16.9 1.0
CA A:ARG277 4.0 14.4 1.0
C A:ARG277 4.0 14.9 1.0
O A:TYR278 4.2 18.5 1.0
O A:TRP276 4.2 13.0 1.0
CG A:TYR278 4.3 16.4 1.0
CG2 A:ILE283 4.4 13.3 1.0
CG1 A:ILE283 4.4 10.2 1.0
NE A:ARG277 4.4 19.6 1.0
CD1 A:TYR270 4.5 18.5 1.0
C A:TYR278 4.5 18.4 1.0
CB A:ILE283 4.5 11.9 1.0
CG A:ARG277 4.6 16.5 1.0
CA A:GLN255 4.6 10.1 1.0
CB A:ARG277 4.9 14.3 1.0
CE2 A:TYR278 4.9 15.7 1.0
CE1 A:TYR270 4.9 22.2 1.0

Chlorine binding site 3 out of 8 in 4n4p

Go back to Chlorine Binding Sites List in 4n4p
Chlorine binding site 3 out of 8 in the Crystal Structure of N-Acetylneuraminate Lyase From Mycoplasma Synoviae, Crystal Form I


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of N-Acetylneuraminate Lyase From Mycoplasma Synoviae, Crystal Form I within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl300

b:18.2
occ:1.00
 O B:HOH488 3.1 20.6 1.0
OG1 B:THR51 3.2 8.8 1.0
N B:THR51 3.3 7.7 1.0
N B:SER50 3.4 7.8 1.0
O B:HOH477 3.4 19.4 1.0
CB B:ALA13 3.5 6.8 1.0
CB B:THR51 3.8 8.4 1.0
CB B:SER50 3.9 9.9 1.0
C B:GLY49 4.0 8.6 1.0
CA B:SER50 4.0 8.8 1.0
CA B:GLY49 4.2 8.1 1.0
C B:SER50 4.2 8.2 1.0
CA B:THR51 4.2 7.6 1.0
CE2 B:TYR46 4.2 8.0 1.0
NZ B:LYS167 4.2 18.6 1.0
CD2 B:TYR46 4.4 7.1 1.0
OG B:SER50 4.5 16.7 1.0
O B:HOH407 4.8 9.4 1.0
OH B:TYR139 4.8 15.0 1.0
CE B:LYS167 4.9 18.0 1.0
CA B:ALA13 4.9 6.8 1.0
O B:GLY49 4.9 7.6 1.0

Chlorine binding site 4 out of 8 in 4n4p

Go back to Chlorine Binding Sites List in 4n4p
Chlorine binding site 4 out of 8 in the Crystal Structure of N-Acetylneuraminate Lyase From Mycoplasma Synoviae, Crystal Form I


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of N-Acetylneuraminate Lyase From Mycoplasma Synoviae, Crystal Form I within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl301

b:20.0
occ:1.00
 O B:HOH424 2.9 11.3 1.0
O B:HOH548 3.0 24.7 1.0
N B:TYR278 3.2 14.2 1.0
O B:HOH422 3.3 11.7 1.0
CB B:TYR278 3.7 15.0 1.0
CD2 B:TYR278 3.7 11.0 1.0
CD B:ARG277 3.8 20.0 1.0
CB B:GLN255 3.8 8.5 1.0
CG B:GLN255 3.8 8.1 1.0
CA B:TYR278 4.0 15.7 1.0
CA B:ARG277 4.1 13.8 1.0
C B:ARG277 4.1 14.5 1.0
O B:TYR278 4.1 16.9 1.0
CG B:TYR278 4.2 12.7 1.0
O B:TRP276 4.3 11.9 1.0
CG2 B:ILE283 4.3 15.0 1.0
CG1 B:ILE283 4.4 12.2 1.0
CB B:ILE283 4.4 14.8 1.0
C B:TYR278 4.5 17.8 1.0
CD1 B:TYR270 4.5 15.1 1.0
CG B:ARG277 4.6 16.2 1.0
NE B:ARG277 4.6 21.1 1.0
CA B:GLN255 4.7 8.0 1.0
CE2 B:TYR278 4.9 12.2 1.0
CB B:ARG277 4.9 14.6 1.0
CE1 B:TYR270 5.0 18.3 1.0

Chlorine binding site 5 out of 8 in 4n4p

Go back to Chlorine Binding Sites List in 4n4p
Chlorine binding site 5 out of 8 in the Crystal Structure of N-Acetylneuraminate Lyase From Mycoplasma Synoviae, Crystal Form I


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Crystal Structure of N-Acetylneuraminate Lyase From Mycoplasma Synoviae, Crystal Form I within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl300

b:20.8
occ:1.00
 O C:HOH448 2.9 18.2 1.0
O C:HOH506 3.1 24.8 1.0
O C:HOH420 3.2 14.2 1.0
N C:TYR278 3.3 18.3 1.0
CB C:TYR278 3.7 19.1 1.0
CD2 C:TYR278 3.8 16.9 1.0
CB C:GLN255 3.8 11.1 1.0
CG C:GLN255 3.8 11.8 1.0
CD C:ARG277 3.9 23.3 1.0
CA C:TYR278 4.0 19.6 1.0
C C:ARG277 4.2 17.7 1.0
CA C:ARG277 4.2 17.3 1.0
O C:TYR278 4.2 21.1 1.0
CG C:TYR278 4.2 18.6 1.0
O C:TRP276 4.3 15.4 1.0
CG2 C:ILE283 4.3 18.7 1.0
CG1 C:ILE283 4.3 17.4 1.0
CD1 C:TYR270 4.4 17.7 1.0
CB C:ILE283 4.5 18.4 1.0
C C:TYR278 4.6 21.1 1.0
CA C:GLN255 4.6 10.8 1.0
NE C:ARG277 4.6 23.2 1.0
CG C:ARG277 4.7 20.6 1.0
CE1 C:TYR270 4.7 20.2 1.0
CE2 C:TYR278 4.9 14.6 1.0
CD1 C:ILE283 4.9 16.9 1.0
CB C:ARG277 5.0 17.6 1.0

Chlorine binding site 6 out of 8 in 4n4p

Go back to Chlorine Binding Sites List in 4n4p
Chlorine binding site 6 out of 8 in the Crystal Structure of N-Acetylneuraminate Lyase From Mycoplasma Synoviae, Crystal Form I


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of Crystal Structure of N-Acetylneuraminate Lyase From Mycoplasma Synoviae, Crystal Form I within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl301

b:20.8
occ:1.00
 O C:HOH467 3.1 20.3 1.0
O C:HOH450 3.2 19.2 1.0
OG1 C:THR51 3.2 12.3 1.0
N C:THR51 3.3 10.6 1.0
N C:SER50 3.5 10.7 1.0
CB C:ALA13 3.5 9.7 1.0
CB C:THR51 3.8 11.1 1.0
CB C:SER50 3.9 12.0 1.0
CA C:SER50 4.0 11.3 1.0
C C:GLY49 4.0 11.1 1.0
CA C:GLY49 4.1 10.6 1.0
C C:SER50 4.1 10.7 1.0
CA C:THR51 4.1 10.8 1.0
CE2 C:TYR46 4.2 10.4 1.0
NZ C:LYS167 4.3 17.1 1.0
CD2 C:TYR46 4.4 11.2 1.0
OG C:SER50 4.5 16.9 1.0
O C:HOH604 4.6 35.8 1.0
O C:HOH401 4.7 9.3 1.0
OH C:TYR139 4.8 12.7 1.0
CA C:ALA13 4.9 9.8 1.0
O C:GLY49 4.9 10.3 1.0
CE C:LYS167 5.0 18.1 1.0

Chlorine binding site 7 out of 8 in 4n4p

Go back to Chlorine Binding Sites List in 4n4p
Chlorine binding site 7 out of 8 in the Crystal Structure of N-Acetylneuraminate Lyase From Mycoplasma Synoviae, Crystal Form I


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 7 of Crystal Structure of N-Acetylneuraminate Lyase From Mycoplasma Synoviae, Crystal Form I within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl300

b:18.1
occ:1.00
 OG1 D:THR51 3.1 11.2 1.0
O D:HOH477 3.1 20.7 1.0
N D:THR51 3.2 9.7 1.0
O D:HOH457 3.5 20.9 1.0
N D:SER50 3.5 10.4 1.0
CB D:ALA13 3.5 10.6 1.0
CB D:THR51 3.7 9.5 1.0
CB D:SER50 3.9 11.3 1.0
CA D:SER50 4.0 11.2 1.0
CA D:THR51 4.1 9.4 1.0
C D:GLY49 4.1 10.4 1.0
C D:SER50 4.1 10.1 1.0
NZ D:LYS167 4.2 14.5 1.0
CE2 D:TYR46 4.3 9.8 1.0
CA D:GLY49 4.3 10.1 1.0
OG D:SER50 4.4 18.7 1.0
CD2 D:TYR46 4.5 9.5 1.0
O D:HOH402 4.8 9.6 1.0
OH D:TYR139 4.9 12.9 1.0
CA D:ALA13 4.9 10.1 1.0
O D:GLY49 4.9 8.5 1.0
O D:HOH499 5.0 23.9 1.0
CE D:LYS167 5.0 15.1 1.0

Chlorine binding site 8 out of 8 in 4n4p

Go back to Chlorine Binding Sites List in 4n4p
Chlorine binding site 8 out of 8 in the Crystal Structure of N-Acetylneuraminate Lyase From Mycoplasma Synoviae, Crystal Form I


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 8 of Crystal Structure of N-Acetylneuraminate Lyase From Mycoplasma Synoviae, Crystal Form I within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl301

b:19.7
occ:1.00
 O D:HOH437 2.9 16.9 1.0
O D:HOH482 3.0 22.0 1.0
O D:HOH405 3.2 11.1 1.0
N D:TYR278 3.3 15.4 1.0
CB D:TYR278 3.7 15.6 1.0
CD2 D:TYR278 3.8 10.4 1.0
CD D:ARG277 3.8 17.3 1.0
CB D:GLN255 3.8 9.4 1.0
CG D:GLN255 3.9 9.9 1.0
CA D:TYR278 4.0 16.5 1.0
O D:TYR278 4.2 17.9 1.0
CA D:ARG277 4.2 14.6 1.0
C D:ARG277 4.2 14.8 1.0
CG D:TYR278 4.2 14.2 1.0
CG2 D:ILE283 4.3 16.4 1.0
CG1 D:ILE283 4.4 14.1 1.0
O D:TRP276 4.4 13.9 1.0
NE D:ARG277 4.5 16.7 1.0
CB D:ILE283 4.5 16.8 1.0
C D:TYR278 4.5 17.9 1.0
CG D:ARG277 4.7 16.0 1.0
CA D:GLN255 4.7 9.3 1.0
CD1 D:TYR270 4.7 17.1 1.0
CE2 D:TYR278 4.9 10.3 1.0
CB D:ARG277 4.9 14.6 1.0
CD1 D:ILE283 5.0 14.8 1.0

Reference:

F.Georgescauld, K.Popova, A.J.Gupta, A.Bracher, J.R.Engen, M.Hayer-Hartl, F.U.Hartl. Groel/Es Chaperonin Modulates the Mechanism and Accelerates the Rate of Tim-Barrel Domain Folding. Cell(Cambridge,Mass.) V. 157 922 2014.
ISSN: ISSN 0092-8674
PubMed: 24813614
DOI: 10.1016/J.CELL.2014.03.038
Page generated: Sat Dec 12 10:57:45 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy