Chlorine in PDB 4n78: The Wave Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton

The structure of The Wave Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton, PDB code: 4n78 was solved by Z.C.Chen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.98 / 2.43
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	97.492, 114.750, 323.605, 90.00, 90.00, 90.00
R / Rfree (%)	18.9 / 20.9

The binding sites of Chlorine atom in the The Wave Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton (pdb code 4n78). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the The Wave Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton, PDB code: 4n78:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the The Wave Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The Wave Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1301 b:84.3 occ:1.00 O A:HOH1589 2.9 59.8 1.0 N A:SER743 3.8 48.1 1.0 N B:ALA1021 3.9 40.5 1.0 CA A:PRO742 3.9 65.3 1.0 CA B:ALA1021 4.1 43.0 1.0 CB B:PRO1020 4.1 43.5 1.0 C B:PRO1020 4.1 48.4 1.0 O B:PRO1020 4.3 53.7 1.0 O A:HOH1558 4.3 46.4 1.0 CB B:ALA1021 4.4 30.8 1.0 C A:PRO742 4.4 52.9 1.0 O B:HOH1426 4.6 62.0 1.0 O A:PRO741 4.6 63.6 1.0 CB A:PRO742 4.6 65.8 1.0 CB A:SER743 4.8 43.0 1.0 CA B:PRO1020 4.8 44.4 1.0 CA A:SER743 4.9 42.4 1.0 N A:PRO742 4.9 70.5 1.0

Chlorine binding site 2 out of 4 in the The Wave Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of The Wave Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1201 b:94.1 occ:1.00 O B:HOH1435 3.0 47.6 1.0 C3 B:GOL1208 3.4 92.6 1.0 NZ B:LYS718 3.5 58.5 1.0 NH2 B:ARG715 3.6 46.0 1.0 NH1 B:ARG611 4.0 42.9 1.0 O3 B:GOL1208 4.1 90.6 1.0 CD B:LYS718 4.2 54.2 1.0 O2 B:GOL1208 4.2 92.0 1.0 C2 B:GOL1208 4.3 93.3 1.0 O B:HOH1380 4.4 45.7 1.0 CE B:LYS718 4.4 56.2 1.0 NE B:ARG715 4.4 54.9 1.0 CZ B:ARG715 4.5 48.6 1.0 C1 B:GOL1208 4.5 93.1 1.0 O B:HOH1519 4.5 63.6 1.0 CZ B:ARG611 4.6 42.9 1.0 NH2 B:ARG611 4.9 42.1 1.0

Chlorine binding site 3 out of 4 in the The Wave Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of The Wave Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1202 b:56.0 occ:1.00 O B:HOH1335 3.0 34.7 1.0 N B:PHE400 3.2 60.0 1.0 NH2 B:ARG343 3.3 39.0 1.0 NH2 B:ARG340 3.3 77.7 1.0 NE B:ARG340 3.3 68.3 1.0 O B:HOH1532 3.4 55.1 1.0 CA B:PHE400 3.4 56.4 1.0 CZ B:ARG340 3.7 77.3 1.0 O B:HOH1508 3.9 58.2 1.0 N B:ILE401 3.9 57.5 1.0 C B:PHE400 4.0 57.9 1.0 CB B:ARG340 4.1 43.6 1.0 O B:GLY336 4.2 45.3 1.0 C B:ASP399 4.3 64.7 1.0 CZ B:ARG343 4.4 42.9 1.0 CD B:ARG340 4.4 56.0 1.0 O B:ASP398 4.5 63.1 1.0 CD1 B:LEU385 4.6 34.4 1.0 O B:ILE401 4.6 61.1 1.0 CD1 B:PHE400 4.6 52.0 1.0 NH1 B:ARG343 4.6 48.5 1.0 CB B:PHE400 4.6 51.5 1.0 CG B:ARG340 4.6 47.5 1.0 CA B:ASP399 4.8 65.3 1.0 CG B:PHE400 4.8 50.3 1.0 CA B:ARG340 4.9 42.6 1.0 NH1 B:ARG340 4.9 82.3 1.0 C B:ILE401 4.9 54.2 1.0 C B:GLY336 5.0 46.5 1.0

Chlorine binding site 4 out of 4 in the The Wave Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of The Wave Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1203 b:0.1 occ:1.00 OD2 B:ASP926 3.2 53.5 0.5 C1 B:GOL1204 3.8 88.7 1.0 CG B:ASP926 4.1 49.5 0.5 O B:ASP926 4.2 44.1 0.5 NH1 B:ARG837 4.3 48.6 1.0 OE2 A:GLU803 4.3 77.5 1.0 O B:ASP926 4.4 44.0 0.5 CD B:ARG837 4.4 41.5 1.0 O1 B:GOL1204 4.4 88.8 1.0 CB B:TYR930 4.6 57.5 1.0 C B:ASP926 4.6 44.3 0.5 CG B:TYR930 4.6 70.8 1.0 CA B:VAL927 4.6 40.4 1.0 C B:ASP926 4.7 44.3 0.5 CZ B:ARG837 4.7 47.1 1.0 NE B:ARG837 4.8 46.8 1.0 OD1 B:ASP926 4.8 54.5 0.5 CG2 B:VAL927 4.8 38.0 1.0 N B:VAL927 4.8 42.5 1.0 CD2 B:TYR930 4.9 78.7 1.0 CB B:ASP926 5.0 44.4 0.5 C3 B:GOL1204 5.0 86.0 1.0

B.Chen, K.Brinkmann, Z.Chen, C.W.Pak, Y.Liao, S.Shi, L.Henry, N.V.Grishin, S.Bogdan, M.K.Rosen. The Wave Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton. Cell(Cambridge,Mass.) V. 156 195 2014.
ISSN: ISSN 0092-8674
PubMed: 24439376
DOI: 10.1016/J.CELL.2013.11.048