Atomistry » Chlorine » PDB 4n99-4ngq » 4n9m
Atomistry »
  Chlorine »
    PDB 4n99-4ngq »
      4n9m »

Chlorine in PDB 4n9m: Joint Neutron/X-Ray Structure of Urate Oxidase in Complex with 8- Hydroxyxanthine

Enzymatic activity of Joint Neutron/X-Ray Structure of Urate Oxidase in Complex with 8- Hydroxyxanthine

All present enzymatic activity of Joint Neutron/X-Ray Structure of Urate Oxidase in Complex with 8- Hydroxyxanthine:
1.7.3.3;

Protein crystallography data

The structure of Joint Neutron/X-Ray Structure of Urate Oxidase in Complex with 8- Hydroxyxanthine, PDB code: 4n9m was solved by E.Oksanen, M.P.Blakeley, M.Budayova-Spano, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) N/A / 2.30
Space group I 2 2 2
Cell size a, b, c (Å), α, β, γ (°) 80.180, 96.260, 105.510, 90.00, 90.00, 90.00
R / Rfree (%) 16.7 / 18.9

Other elements in 4n9m:

The structure of Joint Neutron/X-Ray Structure of Urate Oxidase in Complex with 8- Hydroxyxanthine also contains other interesting chemical elements:

Sodium (Na) 1 atom

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Joint Neutron/X-Ray Structure of Urate Oxidase in Complex with 8- Hydroxyxanthine (pdb code 4n9m). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Joint Neutron/X-Ray Structure of Urate Oxidase in Complex with 8- Hydroxyxanthine, PDB code: 4n9m:

Chlorine binding site 1 out of 1 in 4n9m

Go back to Chlorine Binding Sites List in 4n9m
Chlorine binding site 1 out of 1 in the Joint Neutron/X-Ray Structure of Urate Oxidase in Complex with 8- Hydroxyxanthine


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Joint Neutron/X-Ray Structure of Urate Oxidase in Complex with 8- Hydroxyxanthine within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl402

b:35.6
occ:1.00
 DD21 A:ASN254 2.4 20.8 1.0
HA3 A:GLY286 2.6 13.0 1.0
HB3 A:ASN254 2.9 12.3 1.0
HE1 A:HIS256 3.0 20.4 1.0
ND2 A:ASN254 3.1 20.2 1.0
C4 A:8HX401 3.3 20.5 1.0
C5 A:8HX401 3.3 19.4 1.0
HB2 A:ASN254 3.4 10.4 1.0
CB A:ASN254 3.5 11.9 1.0
HD11 A:ILE288 3.5 12.4 1.0
CA A:GLY286 3.5 10.9 1.0
N9 A:8HX401 3.6 27.3 1.0
N7 A:8HX401 3.6 17.1 1.0
C8 A:8HX401 3.7 19.6 1.0
HA2 A:GLY286 3.7 10.1 1.0
N3 A:8HX401 3.7 14.3 1.0
DD22 A:ASN254 3.7 17.1 1.0
CG A:ASN254 3.8 22.6 1.0
C6 A:8HX401 3.8 23.7 1.0
CE1 A:HIS256 3.8 22.5 1.0
D A:GLY286 3.9 13.4 1.0
DAB A:8HX401 4.0 22.8 1.0
C2 A:8HX401 4.2 9.1 1.0
N1 A:8HX401 4.2 18.6 1.0
N A:GLY286 4.2 10.1 1.0
HD12 A:ILE288 4.3 16.3 1.0
CD1 A:ILE288 4.3 21.1 1.0
NE2 A:HIS256 4.4 15.4 1.0
DAA A:8HX401 4.4 25.9 1.0
O6 A:8HX401 4.4 21.9 1.0
C A:GLY286 4.5 10.3 1.0
O8 A:8HX401 4.5 43.5 1.0
O A:DOD687 4.7 66.0 1.0
D A:LEU287 4.8 10.8 1.0
HG21 A:VAL227 4.8 14.6 1.0
HG12 A:ILE288 4.8 13.1 1.0
HG13 A:ILE288 4.9 18.1 1.0
DAC A:8HX401 4.9 19.0 1.0
CA A:ASN254 4.9 7.4 1.0
D A:ASN254 4.9 10.8 0.5
N A:LEU287 5.0 5.6 1.0
OD1 A:ASN254 5.0 18.5 1.0
ND1 A:HIS256 5.0 17.6 1.0
CG1 A:ILE288 5.0 14.4 1.0

Reference:

E.Oksanen, M.P.Blakeley, M.El-Hajji, U.Ryde, M.Budayova-Spano. The Neutron Structure of Urate Oxidase Resolves A Long-Standing Mechanistic Conundrum and Reveals Unexpected Changes in Protonation. Plos One V. 9 86651 2014.
ISSN: ESSN 1932-6203
PubMed: 24466188
DOI: 10.1371/JOURNAL.PONE.0086651
Page generated: Sun Jul 21 20:33:44 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy