Chlorine in PDB 4nox: Structure of the Nine-Bladed Beta-Propeller of EIF3B

The structure of Structure of the Nine-Bladed Beta-Propeller of EIF3B, PDB code: 4nox was solved by Y.Liu, P.Neumann, B.Kuhle, T.Monecke, R.Ficner, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.47 / 2.72
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	108.380, 108.380, 172.180, 90.00, 90.00, 90.00
R / Rfree (%)	20.6 / 23

The binding sites of Chlorine atom in the Structure of the Nine-Bladed Beta-Propeller of EIF3B (pdb code 4nox). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Structure of the Nine-Bladed Beta-Propeller of EIF3B, PDB code: 4nox:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the Structure of the Nine-Bladed Beta-Propeller of EIF3B


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of the Nine-Bladed Beta-Propeller of EIF3B within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl801 b:99.2 occ:1.00 NE A:ARG168 3.6 94.4 1.0 NH1 A:ARG168 3.8 0.3 1.0 CB A:ARG166 3.9 0.8 1.0 CZ3 A:TRP183 4.1 97.0 1.0 N A:ARG166 4.1 0.8 1.0 CZ A:ARG168 4.1 96.9 1.0 N A:ARG168 4.1 96.0 1.0 N A:GLY167 4.1 0.8 1.0 CH2 A:TRP183 4.2 98.1 1.0 CB A:ARG168 4.3 88.8 1.0 CA A:ARG166 4.4 0.4 1.0 CG A:ARG168 4.5 88.3 1.0 CE3 A:TRP183 4.5 97.1 1.0 CG A:ARG166 4.6 0.6 1.0 CD A:ARG168 4.6 92.2 1.0 C A:ARG166 4.7 0.1 1.0 CZ2 A:TRP183 4.7 96.8 1.0 CA A:ARG168 4.8 90.9 1.0 CA A:GLY167 5.0 0.6 1.0

Chlorine binding site 2 out of 4 in the Structure of the Nine-Bladed Beta-Propeller of EIF3B


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of the Nine-Bladed Beta-Propeller of EIF3B within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl802 b:0.7 occ:1.00 NZ A:LYS532 3.4 73.7 1.0 NH2 A:ARG635 3.7 87.6 1.0 CE A:LYS532 4.1 69.9 1.0 CZ A:ARG635 4.2 89.2 1.0 O A:ARG635 4.3 90.4 1.0 O A:PRO589 4.4 67.4 1.0 CG A:PRO637 4.5 1.0 1.0 CA A:PRO637 4.6 0.4 1.0 NE A:ARG635 4.7 87.1 1.0 CA A:SER590 4.7 59.7 1.0 NH1 A:ARG635 4.7 91.8 1.0 N A:PRO637 4.8 1.0 1.0 CB A:PRO637 4.8 0.7 1.0 C A:PRO589 4.9 63.0 1.0 CD A:PRO637 4.9 0.4 1.0 N A:SER590 5.0 58.5 1.0

Chlorine binding site 3 out of 4 in the Structure of the Nine-Bladed Beta-Propeller of EIF3B


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Structure of the Nine-Bladed Beta-Propeller of EIF3B within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl803 b:1.0 occ:1.00 NZ A:LYS428 3.2 70.6 1.0 NE2 A:HIS417 3.2 54.3 1.0 CE1 A:HIS417 3.7 51.8 1.0 CD A:LYS428 3.8 64.4 1.0 CE A:LYS428 3.8 66.7 1.0 CG A:LYS415 3.9 58.5 1.0 CB A:LYS415 4.0 55.6 1.0 CB A:PHE468 4.1 58.5 1.0 CG1 A:VAL465 4.4 69.1 1.0 CD2 A:HIS417 4.5 55.6 1.0 O A:VAL465 4.7 87.0 1.0 N A:PHE468 4.7 65.9 1.0 CD A:LYS415 4.9 60.1 1.0 C A:ASN467 4.9 67.8 1.0 CB A:VAL465 4.9 72.9 1.0 CG A:LYS428 5.0 56.5 1.0 ND1 A:HIS417 5.0 50.7 1.0 CB A:LYS428 5.0 52.4 1.0

Chlorine binding site 4 out of 4 in the Structure of the Nine-Bladed Beta-Propeller of EIF3B


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Structure of the Nine-Bladed Beta-Propeller of EIF3B within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl804 b:83.2 occ:1.00 ND2 A:ASN467 3.1 82.0 1.0 O A:PHE468 3.9 58.1 1.0 N A:ILE527 4.0 55.4 1.0 O A:ILE527 4.1 56.4 1.0 CB A:ILE527 4.1 50.8 1.0 CG A:ASN467 4.1 79.1 1.0 CB A:ASN467 4.2 72.3 1.0 N A:PHE468 4.4 65.9 1.0 CG1 A:ILE527 4.4 55.0 1.0 CA A:ILE527 4.5 51.9 1.0 C A:PHE468 4.5 56.2 1.0 CD1 A:ILE527 4.5 55.3 1.0 CB A:ALA469 4.6 42.1 1.0 CA A:ASN467 4.7 68.0 1.0 C A:ILE527 4.8 51.8 1.0 C A:ASN467 5.0 67.8 1.0

Y.Liu, P.Neumann, B.Kuhle, T.Monecke, S.Schell, A.Chari, R.Ficner. Translation Initiation Factor EIF3B Contains A Nine-Bladed Beta-Propeller and Interacts with the 40S Ribosomal Subunit Structure V. 22 923 2014.
ISSN: ISSN 0969-2126
PubMed: 24768115
DOI: 10.1016/J.STR.2014.03.010