Chlorine in PDB 4nx2: Crystal Structure of Dcyrs Complexed with Dcy

All present enzymatic activity of Crystal Structure of Dcyrs Complexed with Dcy:
6.1.1.1;

The structure of Crystal Structure of Dcyrs Complexed with Dcy, PDB code: 4nx2 was solved by J.Wang, W.Gong, J.Li, F.Gao, H.Li, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.01 / 2.00
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	53.099, 160.955, 39.009, 90.00, 90.00, 90.00
R / Rfree (%)	17.2 / 22

The binding sites of Chlorine atom in the Crystal Structure of Dcyrs Complexed with Dcy (pdb code 4nx2). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Dcyrs Complexed with Dcy, PDB code: 4nx2:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Dcyrs Complexed with Dcy


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Dcyrs Complexed with Dcy within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl401 b:14.2 occ:1.00 CL1 A:2LT401 0.0 14.2 1.0 CE1 A:2LT401 1.5 35.9 1.0 CD1 A:2LT401 2.5 28.2 1.0 CZ A:2LT401 2.6 29.3 1.0 OH A:2LT401 2.9 36.3 1.0 O A:HOH701 3.2 34.3 1.0 CB A:MET154 3.7 21.1 0.3 O A:HOH501 3.8 8.9 1.0 CA A:GLY70 3.8 18.4 1.0 CG A:2LT401 3.8 37.2 1.0 CE2 A:2LT401 3.8 36.2 1.0 CE A:MET154 3.9 26.4 0.7 CB A:MET154 3.9 21.2 0.7 O A:TYR151 3.9 16.2 1.0 N A:GLN155 3.9 17.9 1.0 CA A:GLN155 4.2 18.1 1.0 CB A:GLN155 4.2 16.6 1.0 N A:GLY70 4.2 19.5 1.0 C A:MET154 4.3 15.9 1.0 CD2 A:2LT401 4.3 27.8 1.0 CB A:ALA67 4.4 18.7 1.0 CE1 A:TYR151 4.6 19.5 1.0 CD1 A:TYR151 4.6 18.0 1.0 CZ A:TYR151 4.7 24.5 1.0 CA A:MET154 4.7 21.9 0.3 OE1 A:GLN155 4.7 27.4 1.0 CA A:MET154 4.7 22.0 0.7 CG A:TYR151 4.7 19.4 1.0 CE2 A:TYR151 4.8 24.7 1.0 CG A:MET154 4.8 25.0 0.3 CD2 A:TYR151 4.8 20.9 1.0 C A:TYR151 4.8 16.4 1.0 O A:MET154 4.9 20.8 1.0 CG A:GLN155 4.9 28.5 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of Dcyrs Complexed with Dcy


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Dcyrs Complexed with Dcy within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl401 b:27.6 occ:1.00 CL2 A:2LT401 0.0 27.6 1.0 CE2 A:2LT401 1.5 36.2 1.0 CZ A:2LT401 2.5 29.3 1.0 CD2 A:2LT401 2.5 27.8 1.0 O A:HOH712 2.7 54.1 1.0 OH A:2LT401 2.7 36.3 1.0 OG A:SER158 3.3 19.1 0.4 CG2 A:ILE65 3.7 20.8 1.0 CA A:GLY34 3.8 13.5 1.0 CB A:ILE65 3.8 19.8 1.0 CG A:GLN155 3.8 28.5 1.0 CG A:2LT401 3.8 37.2 1.0 CE1 A:2LT401 3.8 35.9 1.0 CG1 A:ILE65 4.0 25.7 1.0 N A:GLY34 4.2 13.8 1.0 CB A:SER158 4.2 21.9 0.6 O A:HOH527 4.3 27.0 1.0 CB A:SER158 4.3 21.9 0.4 CD1 A:2LT401 4.3 28.2 1.0 CD A:GLN155 4.4 30.5 1.0 CD1 A:LEU32 4.4 23.3 1.0 OG A:SER158 4.5 20.1 0.6 CA A:GLN155 4.6 18.1 1.0 CB A:GLN155 4.7 16.6 1.0 NE2 A:GLN155 4.7 23.4 1.0 O A:GLN155 4.8 14.8 1.0 C A:GLY34 4.8 19.8 1.0 CD1 A:ILE65 4.9 25.8 1.0 O A:HOH503 4.9 16.1 1.0 C A:ILE33 5.0 12.3 1.0 OE1 A:GLN155 5.0 27.4 1.0

X.Liu, L.Jiang, J.Li, L.Wang, Y.Yu, Q.Zhou, X.Lv, W.Gong, Y.Lu, J.Wang. Significant Expansion of Fluorescent Protein Sensing Ability Through the Genetic Incorporation of Superior Photo-Induced Electron-Transfer Quenchers. J.Am.Chem.Soc. 2014.
ISSN: ESSN 1520-5126
PubMed: 25197956
DOI: 10.1021/JA505219R