Chlorine in PDB 4oae: Crystal Structure of A Gnat Superfamily Acetyltransferase PA4794 C29A/C117A/Y128A Mutant in Complex with Chloramphenicol

The structure of Crystal Structure of A Gnat Superfamily Acetyltransferase PA4794 C29A/C117A/Y128A Mutant in Complex with Chloramphenicol, PDB code: 4oae was solved by K.A.Majorek, M.Chruszcz, A.Joachimiak, W.Minor, Midwest Center Forstructural Genomics (Mcsg), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.96 / 1.25
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	57.880, 75.626, 39.482, 90.00, 90.00, 90.00
R / Rfree (%)	12 / 15.5

The binding sites of Chlorine atom in the Crystal Structure of A Gnat Superfamily Acetyltransferase PA4794 C29A/C117A/Y128A Mutant in Complex with Chloramphenicol (pdb code 4oae). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Crystal Structure of A Gnat Superfamily Acetyltransferase PA4794 C29A/C117A/Y128A Mutant in Complex with Chloramphenicol, PDB code: 4oae:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the Crystal Structure of A Gnat Superfamily Acetyltransferase PA4794 C29A/C117A/Y128A Mutant in Complex with Chloramphenicol


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of A Gnat Superfamily Acetyltransferase PA4794 C29A/C117A/Y128A Mutant in Complex with Chloramphenicol within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl207 b:24.4 occ:0.70 CL1 A:CLM207 0.0 24.4 0.7 C1 A:CLM207 1.8 16.0 0.7 C2 A:CLM207 2.7 15.9 0.7 CL2 A:CLM207 2.9 21.9 0.7 O2 A:CLM207 3.2 15.8 0.7 O A:HOH425 3.3 42.7 1.0 N2 A:CLM207 3.5 12.1 0.7 CD2 A:TYR28 3.7 16.5 1.0 CG A:GLU25 3.7 16.7 1.0 CE2 A:TYR28 3.8 21.0 1.0 OE2 A:GLU25 4.0 19.0 1.0 O A:HOH437 4.0 39.2 1.0 CD A:GLU25 4.2 16.8 1.0 O A:HOH341 4.4 25.2 1.0 C7 A:CLM207 4.5 11.7 0.7 OD1 A:ASN121 4.5 13.8 1.0 CB A:GLU25 4.6 14.0 1.0 CA A:GLU25 4.6 12.7 1.0 C8 A:CLM207 4.7 13.6 0.7 C6 A:CLM207 4.7 12.9 0.7 C3 A:CLM207 4.8 11.5 0.7 NH1 A:ARG88 4.8 18.4 1.0 CG A:TYR28 5.0 15.1 1.0

Chlorine binding site 2 out of 4 in the Crystal Structure of A Gnat Superfamily Acetyltransferase PA4794 C29A/C117A/Y128A Mutant in Complex with Chloramphenicol


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of A Gnat Superfamily Acetyltransferase PA4794 C29A/C117A/Y128A Mutant in Complex with Chloramphenicol within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl207 b:21.9 occ:0.70 CL2 A:CLM207 0.0 21.9 0.7 C1 A:CLM207 1.8 16.0 0.7 C2 A:CLM207 2.7 15.9 0.7 CL1 A:CLM207 2.9 24.4 0.7 O2 A:CLM207 3.0 15.8 0.7 O A:HOH316 3.3 18.5 1.0 O A:HOH341 3.5 25.2 1.0 O A:HOH437 3.6 39.2 1.0 O A:HOH469 3.7 34.8 1.0 CB A:ALA123 3.8 14.4 1.0 N2 A:CLM207 3.8 12.1 0.7 O A:HOH425 4.0 42.7 1.0 O A:HOH461 4.4 55.1 1.0 OD1 A:ASN121 4.6 13.8 1.0

Chlorine binding site 3 out of 4 in the Crystal Structure of A Gnat Superfamily Acetyltransferase PA4794 C29A/C117A/Y128A Mutant in Complex with Chloramphenicol


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of A Gnat Superfamily Acetyltransferase PA4794 C29A/C117A/Y128A Mutant in Complex with Chloramphenicol within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl208 b:25.7 occ:0.80 CL1 A:CLM208 0.0 25.7 0.8 C1 A:CLM208 1.8 23.6 0.8 C2 A:CLM208 2.7 22.6 0.8 CL2 A:CLM208 2.9 38.6 0.8 O2 A:CLM208 3.0 25.9 0.8 N2 A:CLM208 3.8 22.3 0.8 C8 A:CLM208 4.1 29.0 0.8 C7 A:CLM208 4.1 25.0 0.8 C9 A:CLM208 4.7 26.5 0.8 C6 A:CLM208 4.8 21.7 0.8 C3 A:CLM208 5.0 24.7 0.8

Chlorine binding site 4 out of 4 in the Crystal Structure of A Gnat Superfamily Acetyltransferase PA4794 C29A/C117A/Y128A Mutant in Complex with Chloramphenicol


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of A Gnat Superfamily Acetyltransferase PA4794 C29A/C117A/Y128A Mutant in Complex with Chloramphenicol within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl208 b:38.6 occ:0.80 CL2 A:CLM208 0.0 38.6 0.8 C1 A:CLM208 1.8 23.6 0.8 C2 A:CLM208 2.7 22.6 0.8 CL1 A:CLM208 2.9 25.7 0.8 O2 A:CLM208 3.2 25.9 0.8 N2 A:CLM208 3.6 22.3 0.8 C3 A:CLM208 4.9 24.7 0.8

K.A.Majorek, M.Chruszcz, A.Joachimiak, W.Minor. Crystal Structure of A Gnat Superfamily Acetyltransferase PA4794 C29A/C117A/Y128A Mutant in Complex with Chloramphenicol To Be Published.