|
Atomistry » Chlorine » PDB 4oad-4ogn » 4obo | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 4oad-4ogn » 4obo » |
Chlorine in PDB 4obo: MAP4K4 in Complex with Inhibitor (Compound 22), 6-(3-Chlorophenyl) Quinazolin-4-AmineEnzymatic activity of MAP4K4 in Complex with Inhibitor (Compound 22), 6-(3-Chlorophenyl) Quinazolin-4-Amine
All present enzymatic activity of MAP4K4 in Complex with Inhibitor (Compound 22), 6-(3-Chlorophenyl) Quinazolin-4-Amine:
2.7.11.1; Protein crystallography data
The structure of MAP4K4 in Complex with Inhibitor (Compound 22), 6-(3-Chlorophenyl) Quinazolin-4-Amine, PDB code: 4obo
was solved by
S.F.Harris,
P.Wu,
M.Coons,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4obo:
The structure of MAP4K4 in Complex with Inhibitor (Compound 22), 6-(3-Chlorophenyl) Quinazolin-4-Amine also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the MAP4K4 in Complex with Inhibitor (Compound 22), 6-(3-Chlorophenyl) Quinazolin-4-Amine
(pdb code 4obo). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the MAP4K4 in Complex with Inhibitor (Compound 22), 6-(3-Chlorophenyl) Quinazolin-4-Amine, PDB code: 4obo: Chlorine binding site 1 out of 1 in 4oboGo back to Chlorine Binding Sites List in 4obo
Chlorine binding site 1 out
of 1 in the MAP4K4 in Complex with Inhibitor (Compound 22), 6-(3-Chlorophenyl) Quinazolin-4-Amine
Mono view Stereo pair view
Reference:
T.D.Crawford,
C.O.Ndubaku,
H.Chen,
J.W.Boggs,
B.J.Bravo,
K.Delatorre,
A.M.Giannetti,
S.E.Gould,
S.F.Harris,
S.R.Magnuson,
E.Mcnamara,
L.J.Murray,
J.Nonomiya,
A.Sambrone,
S.Schmidt,
T.Smyczek,
M.Stanley,
P.Vitorino,
L.Wang,
K.West,
P.Wu,
W.Ye.
Discovery of Selective 4-Amino-Pyridopyrimidine Inhibitors of MAP4K4 Using Fragment-Based Lead Identification and Optimization. J.Med.Chem. V. 57 3484 2014.
Page generated: Sat Dec 12 11:00:38 2020
ISSN: ISSN 0022-2623 PubMed: 24673130 DOI: 10.1021/JM500155B |
Last articlesZn in 8WB0Zn in 8WAX Zn in 8WAU Zn in 8WAZ Zn in 8WAY Zn in 8WAV Zn in 8WAW Zn in 8WAT Zn in 8W7M Zn in 8WD3 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |