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Atomistry » Chlorine » PDB 4oak-4ogt » 4obo » |
Chlorine in PDB 4obo: MAP4K4 in Complex with Inhibitor (Compound 22), 6-(3-Chlorophenyl) Quinazolin-4-AmineEnzymatic activity of MAP4K4 in Complex with Inhibitor (Compound 22), 6-(3-Chlorophenyl) Quinazolin-4-Amine
All present enzymatic activity of MAP4K4 in Complex with Inhibitor (Compound 22), 6-(3-Chlorophenyl) Quinazolin-4-Amine:
2.7.11.1; Protein crystallography data
The structure of MAP4K4 in Complex with Inhibitor (Compound 22), 6-(3-Chlorophenyl) Quinazolin-4-Amine, PDB code: 4obo
was solved by
S.F.Harris,
P.Wu,
M.Coons,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4obo:
The structure of MAP4K4 in Complex with Inhibitor (Compound 22), 6-(3-Chlorophenyl) Quinazolin-4-Amine also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the MAP4K4 in Complex with Inhibitor (Compound 22), 6-(3-Chlorophenyl) Quinazolin-4-Amine
(pdb code 4obo). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the MAP4K4 in Complex with Inhibitor (Compound 22), 6-(3-Chlorophenyl) Quinazolin-4-Amine, PDB code: 4obo: Chlorine binding site 1 out of 1 in 4oboGo back to![]() ![]()
Chlorine binding site 1 out
of 1 in the MAP4K4 in Complex with Inhibitor (Compound 22), 6-(3-Chlorophenyl) Quinazolin-4-Amine
![]() Mono view ![]() Stereo pair view
Reference:
T.D.Crawford,
C.O.Ndubaku,
H.Chen,
J.W.Boggs,
B.J.Bravo,
K.Delatorre,
A.M.Giannetti,
S.E.Gould,
S.F.Harris,
S.R.Magnuson,
E.Mcnamara,
L.J.Murray,
J.Nonomiya,
A.Sambrone,
S.Schmidt,
T.Smyczek,
M.Stanley,
P.Vitorino,
L.Wang,
K.West,
P.Wu,
W.Ye.
Discovery of Selective 4-Amino-Pyridopyrimidine Inhibitors of MAP4K4 Using Fragment-Based Lead Identification and Optimization. J.Med.Chem. V. 57 3484 2014.
Page generated: Fri Jul 11 19:58:52 2025
ISSN: ISSN 0022-2623 PubMed: 24673130 DOI: 10.1021/JM500155B |
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