Atomistry » Chlorine » PDB 4ogs-4ot7 » 4oj4
Atomistry »
  Chlorine »
    PDB 4ogs-4ot7 »
      4oj4 »

Chlorine in PDB 4oj4: Crystal Structure of V290M Ppargamma Mutant in Complex with Diclofenac

Protein crystallography data

The structure of Crystal Structure of V290M Ppargamma Mutant in Complex with Diclofenac, PDB code: 4oj4 was solved by A.C.Puhl, P.Webb, I.Polikarpov, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 48.19 / 2.30
Space group P 43 21 2
Cell size a, b, c (Å), α, β, γ (°) 60.040, 60.040, 161.190, 90.00, 90.00, 90.00
R / Rfree (%) 21.9 / 28.4

Other elements in 4oj4:

The structure of Crystal Structure of V290M Ppargamma Mutant in Complex with Diclofenac also contains other interesting chemical elements:

Calcium (Ca) 2 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of V290M Ppargamma Mutant in Complex with Diclofenac (pdb code 4oj4). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of V290M Ppargamma Mutant in Complex with Diclofenac, PDB code: 4oj4:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in 4oj4

Go back to Chlorine Binding Sites List in 4oj4
Chlorine binding site 1 out of 2 in the Crystal Structure of V290M Ppargamma Mutant in Complex with Diclofenac


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of V290M Ppargamma Mutant in Complex with Diclofenac within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl501

b:66.7
occ:0.80
CL2 A:DIF501 0.0 66.7 0.8
C2 A:DIF501 1.8 61.8 1.0
C1 A:DIF501 2.7 65.7 1.0
C3 A:DIF501 2.9 59.4 1.0
N1 A:DIF501 3.3 54.5 1.0
O2 A:DIF501 3.7 42.2 1.0
C6 A:DIF501 4.0 64.2 1.0
C A:GLY284 4.1 39.3 1.0
O A:GLY284 4.2 39.2 1.0
C4 A:DIF501 4.2 62.5 1.0
CG2 A:ILE341 4.2 43.0 1.0
C8 A:DIF501 4.2 46.5 1.0
CB A:ILE341 4.3 43.3 1.0
N A:CYS285 4.4 41.7 1.0
CA A:GLY284 4.5 37.9 1.0
C5 A:DIF501 4.6 63.4 1.0
CA A:CYS285 4.6 40.2 1.0
CD1 A:ILE341 4.6 50.7 1.0
CB A:ARG288 4.7 37.8 1.0
C14 A:DIF501 4.8 44.8 1.0
C9 A:DIF501 4.8 49.4 1.0

Chlorine binding site 2 out of 2 in 4oj4

Go back to Chlorine Binding Sites List in 4oj4
Chlorine binding site 2 out of 2 in the Crystal Structure of V290M Ppargamma Mutant in Complex with Diclofenac


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of V290M Ppargamma Mutant in Complex with Diclofenac within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl501

b:63.0
occ:0.80
CL4 A:DIF501 0.0 63.0 0.8
C4 A:DIF501 1.8 62.5 1.0
C5 A:DIF501 2.7 63.4 1.0
C3 A:DIF501 2.8 59.4 1.0
N1 A:DIF501 3.0 54.5 1.0
C8 A:DIF501 3.2 46.5 1.0
C9 A:DIF501 3.3 49.4 1.0
CD1 A:LEU330 3.7 46.2 1.0
CE A:MET364 3.7 51.4 1.0
CG2 A:VAL339 3.9 34.2 1.0
C6 A:DIF501 4.0 64.2 1.0
C2 A:DIF501 4.1 61.8 1.0
CD2 A:LEU330 4.2 48.7 1.0
C7 A:DIF501 4.2 48.2 1.0
C10 A:DIF501 4.2 50.0 1.0
CG A:LEU330 4.3 46.3 1.0
SD A:MET364 4.4 49.6 1.0
CG1 A:VAL339 4.4 31.9 1.0
C1 A:DIF501 4.6 65.7 1.0
SG A:CYS285 4.7 50.0 1.0
CG2 A:ILE341 4.7 43.0 1.0
CB A:VAL339 4.8 34.5 1.0
C13 A:DIF501 5.0 47.2 1.0

Reference:

A.C.Puhl, A.Bernardes, I.Polikarpov, P.Webb. Crystal Structure of A Ppar Ligand-Resistance Syndrome Mutant To Be Published.
Page generated: Sat Dec 12 11:01:09 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy