Chlorine in PDB 4oyw: Crystal Structure of Human Soluble Adenylate Cyclase

All present enzymatic activity of Crystal Structure of Human Soluble Adenylate Cyclase:
4.6.1.1;

The structure of Crystal Structure of Human Soluble Adenylate Cyclase, PDB code: 4oyw was solved by M.Vinkovic, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.71 / 1.70
Space group	P 63
Cell size a, b, c (Å), α, β, γ (°)	99.424, 99.424, 97.391, 90.00, 90.00, 120.00
R / Rfree (%)	18.2 / 21.1

The binding sites of Chlorine atom in the Crystal Structure of Human Soluble Adenylate Cyclase (pdb code 4oyw). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Human Soluble Adenylate Cyclase, PDB code: 4oyw:

Chlorine binding site 1 out of 1 in the Crystal Structure of Human Soluble Adenylate Cyclase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human Soluble Adenylate Cyclase within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl502 b:27.7 occ:1.00 O A:HOH863 2.9 30.6 1.0 NZ A:LYS95 3.0 19.1 1.0 N A:VAL167 3.3 16.2 1.0 CE A:LYS95 3.6 30.2 1.0 CD A:LYS95 3.7 34.6 1.0 CG2 A:VAL167 3.8 19.7 1.0 O A:HOH950 3.9 35.7 1.0 CA A:LEU166 3.9 21.5 1.0 C A:LEU166 4.1 20.2 1.0 CD2 A:LEU102 4.2 20.7 1.0 O A:VAL167 4.4 21.3 1.0 CA A:VAL167 4.4 16.3 1.0 CB A:PHE336 4.4 26.1 1.0 O A:VAL335 4.6 24.6 1.0 O A:PHE165 4.6 14.7 1.0 CA A:PHE336 4.6 23.8 1.0 CD2 A:LEU166 4.6 35.8 1.0 CB A:VAL167 4.6 19.6 1.0 CE1 A:PHE165 4.7 15.6 1.0 O A:HOH895 4.7 41.0 1.0 CB A:LYS95 4.8 15.4 1.0 CB A:LEU166 4.8 25.3 1.0 N A:LEU166 4.8 17.3 1.0 CG A:LYS95 4.9 35.8 1.0 C A:VAL167 4.9 23.5 1.0

S.M.Saalau-Bethell, V.Berdini, A.Cleasby, M.Congreve, J.E.Coyle, V.Lock, C.W.Murray, M.A.O'brien, S.J.Rich, T.Sambrook, M.Vinkovic, J.R.Yon, H.Jhoti. Crystal Structure of Human Soluble Adenylate Cyclase Reveals A Distinct, Highly Flexible Allosteric Bicarbonate Binding Pocket. Chemmedchem V. 9 823 2014.
ISSN: ESSN 1860-7187
PubMed: 24616449
DOI: 10.1002/CMDC.201300480