Chlorine in PDB 4oz1: Crystal Structure of Human Caperalpha Uhm Bound to SF3B155 ULM5

The structure of Crystal Structure of Human Caperalpha Uhm Bound to SF3B155 ULM5, PDB code: 4oz1 was solved by S.Loerch, C.L.Kielkopf, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	33.99 / 1.74
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	44.653, 52.410, 85.141, 90.00, 90.00, 90.00
R / Rfree (%)	14.3 / 18.1

The structure of Crystal Structure of Human Caperalpha Uhm Bound to SF3B155 ULM5 also contains other interesting chemical elements:

Potassium

(K)

1 atom

The binding sites of Chlorine atom in the Crystal Structure of Human Caperalpha Uhm Bound to SF3B155 ULM5 (pdb code 4oz1). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Human Caperalpha Uhm Bound to SF3B155 ULM5, PDB code: 4oz1:

Chlorine binding site 1 out of 1 in the Crystal Structure of Human Caperalpha Uhm Bound to SF3B155 ULM5


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human Caperalpha Uhm Bound to SF3B155 ULM5 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl602 b:26.9 occ:1.00 H B:MET494 2.4 14.4 1.0 HG1 A:THR504 2.4 16.4 1.0 HD21 B:ASN424 2.9 18.3 1.0 HG2 A:PRO501 3.0 18.7 1.0 HG21 A:THR504 3.1 13.0 1.0 HA B:LYS493 3.1 16.4 1.0 O B:HOH692 3.1 19.5 1.0 HD2 A:PRO501 3.1 16.8 1.0 N B:MET494 3.2 12.0 1.0 OG1 A:THR504 3.2 13.7 1.0 HB3 B:LYS493 3.4 19.4 1.0 O A:HOH807 3.4 30.4 1.0 ND2 B:ASN424 3.5 15.3 1.0 HD22 B:ASN424 3.6 18.3 1.0 HG2 B:LYS493 3.6 31.1 1.0 CA B:LYS493 3.8 13.7 1.0 HB3 B:MET494 3.8 14.9 1.0 CD A:PRO501 3.8 14.0 1.0 CG A:PRO501 3.8 15.6 1.0 CG2 A:THR504 3.8 10.9 1.0 CB A:THR504 3.9 11.5 1.0 CB B:LYS493 3.9 16.1 1.0 C B:LYS493 4.0 12.1 1.0 HB A:THR504 4.0 13.8 1.0 HZ3 B:TRP489 4.0 30.4 1.0 HB2 B:MET494 4.0 14.9 1.0 HG23 A:THR504 4.1 13.0 1.0 HD3 A:PRO501 4.1 16.8 1.0 CB B:MET494 4.2 12.4 1.0 CA B:MET494 4.2 10.5 1.0 CG B:LYS493 4.2 25.9 1.0 HB2 A:PRO501 4.3 17.6 1.0 O B:MET494 4.4 10.0 1.0 CZ3 B:TRP489 4.4 25.3 1.0 HD3 B:LYS493 4.5 44.1 1.0 HG3 A:PRO501 4.5 18.7 1.0 HH2 B:TRP489 4.5 30.5 1.0 HG22 A:THR504 4.6 13.0 1.0 CB A:PRO501 4.7 14.7 1.0 CH2 B:TRP489 4.7 25.4 1.0 C B:MET494 4.8 9.7 1.0 CG B:ASN424 4.8 13.9 1.0 HG13 A:VAL500 4.8 15.2 1.0 HB2 B:LYS493 4.8 19.4 1.0 O B:GLY492 4.9 19.9 1.0 CD B:LYS493 4.9 36.8 1.0 O A:HOH821 4.9 26.0 1.0 HG3 B:LYS493 5.0 31.1 1.0 HA B:MET494 5.0 12.7 1.0

S.Loerch, A.Maucuer, V.Manceau, M.R.Green, C.L.Kielkopf. Cancer-Relevant Splicing Factor Caper Alpha Engages the Essential Splicing Factor SF3B155 in A Specific Ternary Complex. J.Biol.Chem. V. 289 17325 2014.
ISSN: ESSN 1083-351X
PubMed: 24795046
DOI: 10.1074/JBC.M114.558825