Chlorine in PDB 4p3m: Crystal Structure of Serine Hydroxymethyltransferase From Psychromonas Ingrahamii

All present enzymatic activity of Crystal Structure of Serine Hydroxymethyltransferase From Psychromonas Ingrahamii:
2.1.2.1;

The structure of Crystal Structure of Serine Hydroxymethyltransferase From Psychromonas Ingrahamii, PDB code: 4p3m was solved by F.Dworkowski, S.Angelaccio, S.Pascarella, G.Capitani, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.61 / 1.85
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	146.820, 64.860, 116.940, 90.00, 125.49, 90.00
R / Rfree (%)	16.9 / 21.2

The binding sites of Chlorine atom in the Crystal Structure of Serine Hydroxymethyltransferase From Psychromonas Ingrahamii (pdb code 4p3m). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Crystal Structure of Serine Hydroxymethyltransferase From Psychromonas Ingrahamii, PDB code: 4p3m:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the Crystal Structure of Serine Hydroxymethyltransferase From Psychromonas Ingrahamii


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Serine Hydroxymethyltransferase From Psychromonas Ingrahamii within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl505 b:23.4 occ:1.00 H A:LEU232 2.4 14.3 1.0 H A:LYS230 2.5 17.9 1.0 HG1 A:THR227 2.5 30.3 1.0 HB2 A:LEU232 2.8 14.3 1.0 HB2 A:LYS230 2.9 15.8 1.0 O A:THR227 3.0 16.0 1.0 O A:HOH653 3.0 16.7 1.0 HG A:LEU232 3.1 21.5 1.0 N A:LYS230 3.2 14.9 1.0 HD12 A:LEU232 3.2 15.7 1.0 H A:THR231 3.2 20.1 1.0 N A:LEU232 3.3 11.9 1.0 OG1 A:THR227 3.3 25.3 1.0 HA A:THR228 3.5 13.1 1.0 C A:THR227 3.5 17.1 1.0 H A:HIS229 3.5 13.0 1.0 N A:THR231 3.5 16.8 1.0 CB A:LEU232 3.5 11.9 1.0 HG1 A:THR226 3.6 16.7 1.0 HB3 A:ALA206 3.6 19.2 1.0 CG A:LEU232 3.6 17.9 1.0 CB A:LYS230 3.6 13.1 1.0 N A:HIS229 3.6 10.8 1.0 CA A:LYS230 3.7 18.9 1.0 C A:LYS230 3.7 15.7 1.0 C A:THR228 3.7 13.7 1.0 CA A:THR228 3.9 10.9 1.0 HG1 A:THR231 3.9 22.2 1.0 CD1 A:LEU232 3.9 13.1 1.0 N A:THR228 3.9 14.8 1.0 CA A:LEU232 4.0 14.6 1.0 HG3 A:LYS230 4.0 18.7 1.0 OG1 A:THR226 4.1 13.9 1.0 HB A:THR227 4.2 21.5 1.0 CB A:THR227 4.2 17.9 1.0 C A:HIS229 4.2 12.8 1.0 O A:THR228 4.3 15.4 1.0 C A:THR231 4.3 10.0 1.0 HB3 A:LEU232 4.3 14.3 1.0 CA A:THR227 4.3 16.9 1.0 H A:GLY233 4.4 13.5 1.0 HB3 A:LYS230 4.4 15.8 1.0 HD11 A:LEU232 4.4 15.7 1.0 CA A:THR231 4.4 15.2 1.0 CB A:ALA206 4.4 16.0 1.0 OG1 A:THR231 4.4 18.5 1.0 CG A:LYS230 4.4 15.6 1.0 CA A:HIS229 4.5 10.9 1.0 HE2 A:LYS230 4.5 37.1 1.0 O A:LYS230 4.5 14.8 1.0 HB1 A:ALA206 4.5 19.2 1.0 H A:THR228 4.6 17.8 1.0 H A:THR227 4.6 15.2 1.0 HB2 A:ALA206 4.6 19.2 1.0 HA A:LYS230 4.6 22.7 1.0 HD13 A:LEU232 4.6 15.7 1.0 HA A:LEU232 4.7 17.5 1.0 N A:THR227 4.7 12.7 1.0 O A:ALA203 4.9 33.9 1.0 HE3 A:LYS230 4.9 37.1 1.0 HA A:HIS229 4.9 13.1 1.0 N A:GLY233 4.9 11.3 1.0 C A:LEU232 5.0 13.1 1.0

Chlorine binding site 2 out of 3 in the Crystal Structure of Serine Hydroxymethyltransferase From Psychromonas Ingrahamii


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Serine Hydroxymethyltransferase From Psychromonas Ingrahamii within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl506 b:21.5 occ:1.00 HH21 A:ARG42 2.3 20.3 1.0 H B:ASN7 2.5 17.6 1.0 HE A:ARG42 2.7 16.8 1.0 HA B:MET6 2.8 18.4 1.0 O B:HOH826 3.1 39.2 1.0 HB2 B:ASP10 3.1 26.3 1.0 NH2 A:ARG42 3.1 16.9 1.0 HB2 B:TYR11 3.1 19.9 1.0 O B:HOH886 3.2 36.1 1.0 N B:ASN7 3.3 14.7 1.0 NE A:ARG42 3.4 14.0 1.0 O B:HOH867 3.4 32.6 1.0 O B:ASN7 3.5 16.5 1.0 CA B:MET6 3.7 15.3 1.0 CZ A:ARG42 3.7 22.2 1.0 HH22 A:ARG42 3.7 20.3 1.0 HG2 B:MET6 3.8 28.3 1.0 HB3 B:MET6 3.9 18.2 1.0 HD21 B:ASN7 4.0 25.1 1.0 CB B:ASP10 4.0 21.9 1.0 ND2 B:ASN7 4.0 20.9 1.0 HD22 B:ASN7 4.0 25.1 1.0 C B:MET6 4.0 14.0 1.0 CB B:TYR11 4.0 16.6 1.0 HB3 B:ASP10 4.1 26.3 1.0 CB B:MET6 4.2 15.2 1.0 H B:TYR11 4.2 18.7 1.0 HB3 B:TYR11 4.3 19.9 1.0 C B:ASN7 4.3 13.6 1.0 CA B:ASN7 4.4 14.6 1.0 N B:TYR11 4.4 15.6 1.0 CG B:ASN7 4.5 19.4 1.0 OD2 B:ASP10 4.5 23.8 1.0 CG B:MET6 4.5 23.6 1.0 O B:ASP5 4.6 22.2 1.0 CD A:ARG42 4.7 14.0 1.0 CA B:TYR11 4.7 13.0 1.0 HA B:TYR11 4.7 15.6 1.0 HD1 B:TYR11 4.7 22.2 1.0 CG B:ASP10 4.8 25.9 1.0 HD3 A:ARG42 4.8 16.8 1.0 N B:MET6 4.8 15.9 1.0 C B:ASP10 4.9 22.1 1.0 HG2 A:ARG42 4.9 16.9 1.0 H B:ASP10 4.9 21.4 1.0 HG3 B:MET6 4.9 28.3 1.0 OD1 B:ASN7 4.9 16.8 1.0 CG B:TYR11 4.9 14.3 1.0 CA B:ASP10 5.0 18.1 1.0

Chlorine binding site 3 out of 3 in the Crystal Structure of Serine Hydroxymethyltransferase From Psychromonas Ingrahamii


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of Serine Hydroxymethyltransferase From Psychromonas Ingrahamii within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl507 b:28.9 occ:1.00 HH21 B:ARG42 2.3 20.4 1.0 H A:ASN7 2.4 21.3 1.0 HE B:ARG42 2.7 22.1 1.0 HA A:MET6 2.9 25.9 1.0 HB2 A:ASP10 3.0 33.9 1.0 HB2 A:TYR11 3.1 18.7 1.0 NH2 B:ARG42 3.1 17.0 1.0 N A:ASN7 3.3 17.7 1.0 O A:HOH833 3.4 46.3 1.0 O A:ASN7 3.4 16.7 1.0 NE B:ARG42 3.5 18.4 1.0 CA A:MET6 3.7 21.6 1.0 HH22 B:ARG42 3.7 20.4 1.0 CZ B:ARG42 3.8 20.2 1.0 CB A:ASP10 3.8 28.2 1.0 HD22 A:ASN7 3.9 27.5 1.0 ND2 A:ASN7 3.9 22.9 1.0 HG2 A:MET6 3.9 29.7 1.0 HB3 A:ASP10 3.9 33.9 1.0 HD21 A:ASN7 3.9 27.5 1.0 HB3 A:MET6 3.9 16.6 1.0 CB A:TYR11 4.0 15.6 1.0 C A:MET6 4.0 13.1 1.0 HB3 A:TYR11 4.2 18.7 1.0 C A:ASN7 4.2 14.9 1.0 CB A:MET6 4.3 13.8 1.0 CA A:ASN7 4.3 15.3 1.0 CG A:ASN7 4.3 22.4 1.0 H A:TYR11 4.4 16.9 1.0 OD2 A:ASP10 4.4 44.6 1.0 N A:TYR11 4.5 14.1 1.0 CG A:MET6 4.5 24.7 1.0 CG A:ASP10 4.6 41.3 1.0 O A:ASP5 4.7 27.3 1.0 CD B:ARG42 4.7 12.4 1.0 H A:ASP10 4.8 24.8 1.0 OD1 A:ASN7 4.8 20.2 1.0 CA A:TYR11 4.8 16.7 1.0 C A:ASP10 4.8 20.7 1.0 HD1 A:TYR11 4.8 18.6 1.0 HA A:TYR11 4.8 20.0 1.0 N A:MET6 4.8 19.7 1.0 HG2 B:ARG42 4.8 14.8 1.0 CA A:ASP10 4.9 26.4 1.0 HD3 B:ARG42 4.9 14.9 1.0 CB A:ASN7 4.9 16.1 1.0 CG A:TYR11 4.9 15.2 1.0 HG3 A:MET6 5.0 29.7 1.0

S.Angelaccio, F.Dworkowski, A.Di Bello, T.Milano, G.Capitani, S.Pascarella. Conformational Transitions Driven By Pyridoxal-5'-Phosphate Uptake in the Psychrophilic Serine Hydroxymethyltransferase From Psychromonas Ingrahamii. Proteins V. 82 2831 2014.
ISSN: ESSN 1097-0134
PubMed: 25044250
DOI: 10.1002/PROT.24646