Chlorine in PDB 4pan: A Conserved Phenylalanine As Relay Between the 5 Helix and the Gdp Binding Region of Heterotrimeric G Protein

The structure of A Conserved Phenylalanine As Relay Between the 5 Helix and the Gdp Binding Region of Heterotrimeric G Protein, PDB code: 4pan was solved by A.I.Kaya, A.D.Lokits, J.Gilbert, T.M.Iverson, J.Meiler, H.E.Hamm, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.40
Space group	I 4
Cell size a, b, c (Å), α, β, γ (°)	121.533, 121.533, 68.279, 90.00, 90.00, 90.00
R / Rfree (%)	18.2 / 23.2

The binding sites of Chlorine atom in the A Conserved Phenylalanine As Relay Between the 5 Helix and the Gdp Binding Region of Heterotrimeric G Protein (pdb code 4pan). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the A Conserved Phenylalanine As Relay Between the 5 Helix and the Gdp Binding Region of Heterotrimeric G Protein, PDB code: 4pan:

Chlorine binding site 1 out of 1 in the A Conserved Phenylalanine As Relay Between the 5 Helix and the Gdp Binding Region of Heterotrimeric G Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of A Conserved Phenylalanine As Relay Between the 5 Helix and the Gdp Binding Region of Heterotrimeric G Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl403 b:32.2 occ:1.00 NH1 A:ARG178 3.0 36.8 1.0 O A:HOH561 3.0 31.5 1.0 O A:HOH543 3.3 19.0 1.0 N A:ASP150 3.3 21.6 1.0 C4' A:GDP401 3.5 19.9 1.0 OD2 A:ASP150 3.6 28.5 1.0 CG A:GLU43 3.6 29.9 1.0 NZ A:LYS270 3.7 25.1 1.0 CB A:ASP150 3.7 26.1 1.0 CG A:ASP150 3.8 31.9 1.0 O4' A:GDP401 3.8 20.7 1.0 CD A:ARG178 3.9 34.0 1.0 C5' A:GDP401 4.0 19.7 1.0 CZ A:ARG178 4.1 40.2 1.0 CA A:ASP150 4.1 24.1 1.0 OE1 A:GLU43 4.1 40.9 1.0 CD A:GLU43 4.2 45.4 1.0 CA A:ASN149 4.2 25.6 1.0 CB A:GLU43 4.3 23.9 1.0 C A:ASN149 4.3 26.1 1.0 NE A:ARG178 4.4 37.0 1.0 OD1 A:ASP150 4.5 31.6 1.0 O3' A:GDP401 4.6 17.5 1.0 C3' A:GDP401 4.7 19.8 1.0 O A:HOH564 4.7 27.3 1.0 O A:LEU148 5.0 23.9 1.0 C1' A:GDP401 5.0 20.3 1.0

A.I.Kaya, A.D.Lokits, J.A.Gilbert, T.M.Iverson, J.Meiler, H.E.Hamm. A Conserved Phenylalanine As A Relay Between the Alpha 5 Helix and the Gdp Binding Region of Heterotrimeric Gi Protein Alpha Subunit. J.Biol.Chem. V. 289 24475 2014.
ISSN: ESSN 1083-351X
PubMed: 25037222
DOI: 10.1074/JBC.M114.572875