Chlorine in PDB 4pkl: Bromodomain of Trypanosoma Brucei BDF2 with Ibet-151

The structure of Bromodomain of Trypanosoma Brucei BDF2 with Ibet-151, PDB code: 4pkl was solved by E.W.Debler, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	31.06 / 1.25
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	55.869, 62.091, 62.117, 90.00, 90.00, 90.00
R / Rfree (%)	16.9 / 17.9

The structure of Bromodomain of Trypanosoma Brucei BDF2 with Ibet-151 also contains other interesting chemical elements:

Potassium

(K)

2 atoms

The binding sites of Chlorine atom in the Bromodomain of Trypanosoma Brucei BDF2 with Ibet-151 (pdb code 4pkl). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Bromodomain of Trypanosoma Brucei BDF2 with Ibet-151, PDB code: 4pkl:

Chlorine binding site 1 out of 1 in the Bromodomain of Trypanosoma Brucei BDF2 with Ibet-151


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Bromodomain of Trypanosoma Brucei BDF2 with Ibet-151 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl204 b:39.0 occ:1.00 N A:LYS88 3.6 16.0 1.0 CA A:ALA87 4.0 15.0 1.0 K A:K203 4.0 17.1 1.0 O A:HOH312 4.2 19.4 1.0 CB A:ALA87 4.2 15.5 1.0 CB A:LYS88 4.3 19.0 1.0 C A:ALA87 4.3 14.2 1.0 CA A:LYS88 4.6 18.2 1.0 O A:HOH420 4.8 40.3 1.0 O A:ASN86 4.9 15.8 1.0

D.Schulz, M.Mugnier, E.Paulsen, H.Kim, C.Chung, D.F.Tough, I.Rioja, R.K.Prinjha, N.Papavasiliou, E.W.Debler. Bromodomain Proteins Regulate Mono- Allelic Expression and Switching of T. Brucei Variant Surface Glycoprotein To Be Published.