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Atomistry » Chlorine » PDB 4pwl-4q57 » 4pyv | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 4pwl-4q57 » 4pyv » |
Chlorine in PDB 4pyv: Crystal Structure of Renin in Complex with COMPOUND4Enzymatic activity of Crystal Structure of Renin in Complex with COMPOUND4
All present enzymatic activity of Crystal Structure of Renin in Complex with COMPOUND4:
3.4.23.15; Protein crystallography data
The structure of Crystal Structure of Renin in Complex with COMPOUND4, PDB code: 4pyv
was solved by
N.Ostermann,
F.Zink,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Renin in Complex with COMPOUND4
(pdb code 4pyv). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Crystal Structure of Renin in Complex with COMPOUND4, PDB code: 4pyv: Jump to Chlorine binding site number: 1; 2; 3; 4; Chlorine binding site 1 out of 4 in 4pyvGo back to Chlorine Binding Sites List in 4pyv
Chlorine binding site 1 out
of 4 in the Crystal Structure of Renin in Complex with COMPOUND4
Mono view Stereo pair view
Chlorine binding site 2 out of 4 in 4pyvGo back to Chlorine Binding Sites List in 4pyv
Chlorine binding site 2 out
of 4 in the Crystal Structure of Renin in Complex with COMPOUND4
Mono view Stereo pair view
Chlorine binding site 3 out of 4 in 4pyvGo back to Chlorine Binding Sites List in 4pyv
Chlorine binding site 3 out
of 4 in the Crystal Structure of Renin in Complex with COMPOUND4
Mono view Stereo pair view
Chlorine binding site 4 out of 4 in 4pyvGo back to Chlorine Binding Sites List in 4pyv
Chlorine binding site 4 out
of 4 in the Crystal Structure of Renin in Complex with COMPOUND4
Mono view Stereo pair view
Reference:
T.Ehara,
O.Irie,
T.Kosaka,
T.Kanazawa,
W.Breitenstein,
P.Grosche,
N.Ostermann,
M.Suzuki,
S.Kawakami,
K.Konishi,
Y.Hitomi,
A.Toyao,
H.Gunji,
F.Cumin,
N.Schiering,
T.Wagner,
D.F.Rigel,
R.L.Webb,
J.Maibaum,
F.Yokokawa.
Structure-Based Design of Substituted Piperidines As A New Class of Highly Efficacious Oral Direct Renin Inhibitors. Acs Med Chem Lett V. 5 787 2014.
Page generated: Sat Dec 12 11:04:20 2020
PubMed: 25050166 DOI: 10.1021/ML500137B |
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