Atomistry » Chlorine » PDB 4pwl-4q57 » 4q33
Atomistry »
  Chlorine »
    PDB 4pwl-4q57 »
      4q33 »

Chlorine in PDB 4q33: Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and A110

Enzymatic activity of Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and A110

All present enzymatic activity of Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and A110:
1.1.1.205;

Protein crystallography data

The structure of Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and A110, PDB code: 4q33 was solved by N.Maltseva, Y.Kim, M.Makowska-Grzyska, R.Mulligan, M.Gu, M.Zhang, K.Mandapati, D.R.Gollapalli, S.K.Gorla, L.Hedstrom, W.F.Anderson, A.Joachimiak, Center For Structural Genomics Of Infectious Diseases(Csgid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 37.21 / 2.88
Space group P 1
Cell size a, b, c (Å), α, β, γ (°) 88.121, 89.247, 99.185, 70.82, 72.66, 79.30
R / Rfree (%) 18.5 / 24.3

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and A110 (pdb code 4q33). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 8 binding sites of Chlorine where determined in the Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and A110, PDB code: 4q33:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8;

Chlorine binding site 1 out of 8 in 4q33

Go back to Chlorine Binding Sites List in 4q33
Chlorine binding site 1 out of 8 in the Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and A110


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and A110 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl501

b:65.6
occ:1.00
 CL1 A:2YA501 0.0 65.6 1.0
C19 A:2YA501 1.8 49.6 1.0
C18 A:2YA501 2.8 49.1 1.0
C20 A:2YA501 2.8 50.2 1.0
C C:GLY439 3.3 43.4 1.0
O C:GLY439 3.3 45.4 1.0
CB A:HIS249 3.5 45.2 1.0
N C:TYR440 3.5 38.0 1.0
CA C:GLY439 3.8 45.6 1.0
CG A:HIS249 3.9 41.3 1.0
CA C:TYR440 4.0 35.5 1.0
CD2 A:HIS249 4.0 41.6 1.0
C17 A:2YA501 4.1 50.7 1.0
C21 A:2YA501 4.1 51.1 1.0
CG C:PRO25 4.2 51.0 1.0
CD C:PRO25 4.2 48.1 1.0
O C:SER436 4.3 42.8 1.0
CG C:TYR440 4.3 44.6 1.0
CD1 C:TYR440 4.4 38.6 1.0
CD2 C:TYR440 4.6 38.9 1.0
C16 A:2YA501 4.6 52.8 1.0
CE1 C:TYR440 4.7 40.6 1.0
CB C:TYR440 4.7 34.7 1.0
CE2 C:TYR440 4.9 40.5 1.0
O C:VAL23 4.9 51.3 1.0
CA A:HIS249 4.9 45.9 1.0
CZ C:TYR440 4.9 40.4 1.0
N C:GLY439 4.9 43.8 1.0

Chlorine binding site 2 out of 8 in 4q33

Go back to Chlorine Binding Sites List in 4q33
Chlorine binding site 2 out of 8 in the Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and A110


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and A110 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl502

b:64.9
occ:1.00
 CL1 B:2YA502 0.0 64.9 1.0
C19 B:2YA502 1.8 65.6 1.0
C18 B:2YA502 2.8 69.9 1.0
C20 B:2YA502 2.8 62.0 1.0
O A:GLY439 3.2 44.4 1.0
C A:GLY439 3.2 41.0 1.0
CD2 B:HIS249 3.6 55.1 1.0
CA A:GLY439 3.6 40.4 1.0
N A:TYR440 3.7 38.7 1.0
CB B:HIS249 3.9 52.8 1.0
CG B:HIS249 4.0 53.9 1.0
C17 B:2YA502 4.1 68.3 1.0
C21 B:2YA502 4.1 61.8 1.0
O A:SER436 4.2 37.0 1.0
CA A:TYR440 4.2 39.9 1.0
CD A:PRO25 4.2 71.2 1.0
CG A:PRO25 4.3 69.9 1.0
O A:VAL23 4.3 55.9 1.0
CD1 A:TYR440 4.4 45.4 1.0
CG A:TYR440 4.5 41.6 1.0
CE1 A:TYR440 4.6 51.9 1.0
C16 B:2YA502 4.6 66.2 1.0
N A:GLY439 4.7 38.8 1.0
CD2 A:TYR440 4.7 48.2 1.0
NE2 B:HIS249 4.8 55.0 1.0
CZ A:TYR440 4.8 55.5 1.0
CE2 A:TYR440 4.9 53.2 1.0
CB A:TYR440 4.9 37.2 1.0
OG A:SER21 5.0 51.3 1.0

Chlorine binding site 3 out of 8 in 4q33

Go back to Chlorine Binding Sites List in 4q33
Chlorine binding site 3 out of 8 in the Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and A110


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and A110 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl503

b:69.1
occ:1.00
 CL1 B:2YA503 0.0 69.1 1.0
C19 B:2YA503 1.8 64.7 1.0
C18 B:2YA503 2.8 64.6 1.0
C20 B:2YA503 2.8 63.2 1.0
C B:GLY439 3.2 52.6 1.0
O B:GLY439 3.3 50.0 1.0
N B:TYR440 3.5 55.1 1.0
CA B:GLY439 3.7 48.9 1.0
CD2 D:HIS249 3.9 62.2 1.0
CD B:PRO25 4.0 71.0 1.0
CB D:HIS249 4.0 62.9 1.0
CA B:TYR440 4.1 51.4 1.0
C17 B:2YA503 4.1 65.6 1.0
C21 B:2YA503 4.1 64.7 1.0
CG D:HIS249 4.3 60.0 1.0
CG B:PRO25 4.4 66.7 1.0
O B:SER436 4.5 51.6 1.0
O B:VAL23 4.5 60.2 1.0
OG B:SER21 4.5 63.9 1.0
C16 B:2YA503 4.6 68.6 1.0
CG B:TYR440 4.6 51.7 1.0
CD2 B:LEU24 4.8 60.5 1.0
CD1 B:TYR440 4.8 50.2 1.0
N B:GLY439 4.9 46.8 1.0
CD2 B:TYR440 4.9 56.2 1.0
CB B:TYR440 4.9 50.0 1.0

Chlorine binding site 4 out of 8 in 4q33

Go back to Chlorine Binding Sites List in 4q33
Chlorine binding site 4 out of 8 in the Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and A110


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and A110 within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl501

b:91.3
occ:1.00
 CL1 C:2YA501 0.0 91.3 1.0
C19 C:2YA501 1.8 66.1 1.0
C18 C:2YA501 2.8 65.8 1.0
C20 C:2YA501 2.8 63.4 1.0
C D:GLY439 3.2 40.9 1.0
O D:GLY439 3.4 44.0 1.0
N D:TYR440 3.5 40.4 1.0
CA D:GLY439 3.6 41.5 1.0
CB C:HIS249 3.9 49.7 1.0
CA D:TYR440 4.0 42.5 1.0
C17 C:2YA501 4.1 64.0 1.0
C21 C:2YA501 4.1 61.6 1.0
CD2 C:HIS249 4.1 51.9 1.0
O D:SER436 4.2 44.7 1.0
CD D:PRO25 4.3 55.2 1.0
CD1 D:TYR440 4.3 45.0 1.0
CG D:TYR440 4.3 41.4 1.0
CG C:HIS249 4.3 49.0 1.0
CG D:PRO25 4.4 50.2 1.0
CE1 D:TYR440 4.6 50.2 1.0
CD2 D:TYR440 4.6 40.4 1.0
C16 C:2YA501 4.6 63.7 1.0
CB D:TYR440 4.7 43.8 1.0
N D:GLY439 4.8 43.2 1.0
CZ D:TYR440 4.8 46.8 1.0
CE2 D:TYR440 4.8 43.8 1.0
O D:VAL23 4.9 59.2 1.0

Chlorine binding site 5 out of 8 in 4q33

Go back to Chlorine Binding Sites List in 4q33
Chlorine binding site 5 out of 8 in the Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and A110


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and A110 within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Cl501

b:78.0
occ:1.00
 CL1 E:2YA501 0.0 78.0 1.0
C19 E:2YA501 1.8 69.5 1.0
C18 E:2YA501 2.8 68.2 1.0
C20 E:2YA501 2.8 65.1 1.0
O G:GLY439 3.1 40.2 1.0
C G:GLY439 3.2 37.0 1.0
CA G:GLY439 3.7 39.5 1.0
N G:TYR440 3.7 36.4 1.0
CD2 E:HIS249 3.8 63.0 1.0
CB E:HIS249 3.8 63.6 1.0
C17 E:2YA501 4.1 63.1 1.0
C21 E:2YA501 4.1 62.5 1.0
CG E:HIS249 4.1 62.4 1.0
CD G:PRO25 4.2 69.9 1.0
CA G:TYR440 4.2 37.1 1.0
O G:VAL23 4.3 60.2 1.0
CG G:PRO25 4.3 67.5 1.0
O G:SER436 4.6 36.6 1.0
C16 E:2YA501 4.6 64.8 1.0
OG G:SER21 4.7 47.2 1.0
CG G:TYR440 4.8 36.5 1.0
N G:GLY439 4.9 41.9 1.0
CD2 G:TYR440 5.0 35.0 1.0
N G:PRO25 5.0 69.2 1.0
CD1 G:TYR440 5.0 42.0 1.0

Chlorine binding site 6 out of 8 in 4q33

Go back to Chlorine Binding Sites List in 4q33
Chlorine binding site 6 out of 8 in the Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and A110


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and A110 within 5.0Å range:
probe atom residue distance (Å) B Occ
F:Cl501

b:64.4
occ:1.00
 CL1 F:2YA501 0.0 64.4 1.0
C19 F:2YA501 1.8 44.1 1.0
C18 F:2YA501 2.8 41.4 1.0
C20 F:2YA501 2.8 46.1 1.0
C E:GLY439 3.2 44.8 1.0
O E:GLY439 3.3 50.0 1.0
N E:TYR440 3.5 40.3 1.0
CA E:GLY439 3.7 46.5 1.0
CD2 F:HIS249 3.7 44.0 1.0
CB F:HIS249 3.8 43.0 1.0
CD E:PRO25 4.0 55.6 1.0
CG F:HIS249 4.0 40.7 1.0
C17 F:2YA501 4.1 42.1 1.0
C21 F:2YA501 4.1 46.9 1.0
CA E:TYR440 4.1 44.1 1.0
CG E:PRO25 4.4 45.2 1.0
CD1 E:TYR440 4.4 50.9 1.0
CG E:TYR440 4.5 50.3 1.0
O E:VAL23 4.5 44.0 1.0
O E:SER436 4.6 52.2 1.0
C16 F:2YA501 4.6 45.9 1.0
CE1 E:TYR440 4.7 51.7 1.0
N E:GLY439 4.8 50.5 1.0
CD2 E:TYR440 4.9 50.5 1.0
NE2 F:HIS249 4.9 46.5 1.0
CB E:TYR440 4.9 47.8 1.0

Chlorine binding site 7 out of 8 in 4q33

Go back to Chlorine Binding Sites List in 4q33
Chlorine binding site 7 out of 8 in the Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and A110


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 7 of Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and A110 within 5.0Å range:
probe atom residue distance (Å) B Occ
G:Cl501

b:65.7
occ:1.00
 CL1 G:2YA501 0.0 65.7 1.0
C19 G:2YA501 1.8 66.4 1.0
C18 G:2YA501 2.7 68.4 1.0
C20 G:2YA501 2.8 66.4 1.0
C H:GLY439 3.1 50.5 1.0
O H:GLY439 3.3 56.9 1.0
CA H:GLY439 3.5 53.6 1.0
N H:TYR440 3.5 42.2 1.0
CD2 G:HIS249 3.8 37.0 1.0
CD H:PRO25 3.9 56.6 1.0
CB G:HIS249 4.0 38.9 1.0
C17 G:2YA501 4.0 69.6 1.0
CA H:TYR440 4.1 39.9 1.0
C21 G:2YA501 4.1 67.8 1.0
CG G:HIS249 4.2 37.2 1.0
O H:VAL23 4.4 40.8 1.0
O H:SER436 4.6 49.5 1.0
C16 G:2YA501 4.6 70.8 1.0
CG H:PRO25 4.7 55.5 1.0
CG H:TYR440 4.7 39.0 1.0
N H:GLY439 4.7 54.3 1.0
OG H:SER21 4.8 39.9 1.0
C G:FMT502 4.8 44.4 1.0
CD1 H:TYR440 4.8 41.5 1.0
NE2 G:HIS249 4.9 37.3 1.0
CB H:TYR440 5.0 36.7 1.0
CD2 H:TYR440 5.0 40.1 1.0

Chlorine binding site 8 out of 8 in 4q33

Go back to Chlorine Binding Sites List in 4q33
Chlorine binding site 8 out of 8 in the Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and A110


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 8 of Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and A110 within 5.0Å range:
probe atom residue distance (Å) B Occ
H:Cl501

b:77.5
occ:1.00
 CL1 H:2YA501 0.0 77.5 1.0
C19 H:2YA501 1.8 54.9 1.0
C20 H:2YA501 2.8 53.2 1.0
C18 H:2YA501 2.8 55.5 1.0
C F:GLY439 3.5 41.6 1.0
O F:GLY439 3.5 43.7 1.0
CB H:HIS249 3.6 46.2 1.0
N F:TYR440 3.7 39.5 1.0
CD2 H:HIS249 3.9 55.3 1.0
C21 H:2YA501 4.1 57.1 1.0
C17 H:2YA501 4.1 58.5 1.0
CA F:TYR440 4.1 40.5 1.0
CG H:HIS249 4.1 53.0 1.0
CA F:GLY439 4.1 41.5 1.0
CG F:TYR440 4.5 35.4 1.0
CD F:PRO25 4.5 57.9 1.0
CD1 F:TYR440 4.5 36.2 1.0
C16 H:2YA501 4.6 62.6 1.0
CG F:PRO25 4.7 46.0 1.0
O F:SER436 4.7 35.5 1.0
CD2 F:TYR440 4.8 34.3 1.0
CE1 F:TYR440 4.8 40.5 1.0
CB F:TYR440 4.9 36.8 1.0
O F:VAL23 4.9 58.6 1.0
CA H:HIS249 5.0 42.6 1.0

Reference:

N.Maltseva, Y.Kim, M.Makowska-Grzyska, R.Mulligan, M.Gu, M.Zhang, K.Mandapati, D.R.Gollapalli, S.K.Gorla, L.Hedstrom, W.F.Anderson, A.Joachimiak. Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and A110 To Be Published.
Page generated: Sat Dec 12 11:04:32 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy