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Chlorine in PDB 4ra0: An Engineered Axl 'Decoy Receptor' Effectively Silences the GAS6-Axl Signaling Axis
Enzymatic activity of An Engineered Axl 'Decoy Receptor' Effectively Silences the GAS6-Axl Signaling Axis
All present enzymatic activity of An Engineered Axl 'Decoy Receptor' Effectively Silences the GAS6-Axl Signaling Axis:
2.7.10.1;
2.7.10.1;
Protein crystallography data
The structure of An Engineered Axl 'Decoy Receptor' Effectively Silences the GAS6-Axl Signaling Axis, PDB code: 4ra0
was solved by
M.S.Kariolis,
S.Kapur,
I.I.Mathews,
J.R.Cochran,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 38.01 / 3.07 |
| Space group | P 32 2 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 112.370, 112.370, 361.260, 90.00, 90.00, 120.00 |
| R / Rfree (%) | 20.2 / 24.3 |
Other elements in 4ra0:
The structure of An Engineered Axl 'Decoy Receptor' Effectively Silences the GAS6-Axl Signaling Axis also contains other interesting chemical elements:
| Nickel | (Ni) | 2 atoms |
| Calcium | (Ca) | 2 atoms |
Chlorine Binding Sites:
The binding sites of Chlorine atom in the An Engineered Axl 'Decoy Receptor' Effectively Silences the GAS6-Axl Signaling Axis
(pdb code 4ra0). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the An Engineered Axl 'Decoy Receptor' Effectively Silences the GAS6-Axl Signaling Axis, PDB code: 4ra0:
In total only one binding site of Chlorine was determined in the An Engineered Axl 'Decoy Receptor' Effectively Silences the GAS6-Axl Signaling Axis, PDB code: 4ra0:
Chlorine binding site 1 out of 1 in 4ra0
Go back to
Chlorine Binding Sites List in 4ra0
Chlorine binding site 1 out
of 1 in the An Engineered Axl 'Decoy Receptor' Effectively Silences the GAS6-Axl Signaling Axis
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of An Engineered Axl 'Decoy Receptor' Effectively Silences the GAS6-Axl Signaling Axis within 5.0Å range:
|
Reference:
M.S.Kariolis,
Y.R.Miao,
D.S.Jones,
S.Kapur,
I.I.Mathews,
A.J.Giaccia,
J.R.Cochran.
An Engineered Axl 'Decoy Receptor' Effectively Silences the GAS6-Axl Signaling Axis. Nat.Chem.Biol. V. 10 977 2014.
ISSN: ISSN 1552-4450
PubMed: 25242553
DOI: 10.1038/NCHEMBIO.1636
Page generated: Fri Jul 11 21:18:40 2025
ISSN: ISSN 1552-4450
PubMed: 25242553
DOI: 10.1038/NCHEMBIO.1636
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