Atomistry » Chlorine » PDB 4rsh-4s27 » 4rte
Atomistry »
  Chlorine »
    PDB 4rsh-4s27 »
      4rte »

Chlorine in PDB 4rte: The X-Ray Structure of Bovine Pancreatic Ribonuclease Incubated in the Presence of An Excess of Cisplatin (1:10 Ratio)

Enzymatic activity of The X-Ray Structure of Bovine Pancreatic Ribonuclease Incubated in the Presence of An Excess of Cisplatin (1:10 Ratio)

All present enzymatic activity of The X-Ray Structure of Bovine Pancreatic Ribonuclease Incubated in the Presence of An Excess of Cisplatin (1:10 Ratio):
3.1.27.5;

Protein crystallography data

The structure of The X-Ray Structure of Bovine Pancreatic Ribonuclease Incubated in the Presence of An Excess of Cisplatin (1:10 Ratio), PDB code: 4rte was solved by I.Russo Krauss, A.Merlino, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 55.23 / 1.95
Space group P 32 2 1
Cell size a, b, c (Å), α, β, γ (°) 63.770, 63.770, 63.575, 90.00, 90.00, 120.00
R / Rfree (%) 16.7 / 22.4

Other elements in 4rte:

The structure of The X-Ray Structure of Bovine Pancreatic Ribonuclease Incubated in the Presence of An Excess of Cisplatin (1:10 Ratio) also contains other interesting chemical elements:

Platinum (Pt) 4 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the The X-Ray Structure of Bovine Pancreatic Ribonuclease Incubated in the Presence of An Excess of Cisplatin (1:10 Ratio) (pdb code 4rte). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 6 binding sites of Chlorine where determined in the The X-Ray Structure of Bovine Pancreatic Ribonuclease Incubated in the Presence of An Excess of Cisplatin (1:10 Ratio), PDB code: 4rte:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6;

Chlorine binding site 1 out of 6 in 4rte

Go back to Chlorine Binding Sites List in 4rte
Chlorine binding site 1 out of 6 in the The X-Ray Structure of Bovine Pancreatic Ribonuclease Incubated in the Presence of An Excess of Cisplatin (1:10 Ratio)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The X-Ray Structure of Bovine Pancreatic Ribonuclease Incubated in the Presence of An Excess of Cisplatin (1:10 Ratio) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl501

b:36.3
occ:0.40
CL1 A:CPT501 0.0 36.3 0.4
CL A:CL507 1.0 21.1 0.4
PT1 A:CPT501 2.3 48.1 0.4
O A:HOH757 2.6 55.0 1.0
O A:HOH633 2.9 39.9 1.0
N1 A:CPT501 3.1 38.2 0.4
N A:PHE120 3.2 23.7 1.0
NE2 A:HIS12 3.3 21.2 1.0
ND1 A:HIS119 3.4 48.5 1.0
O A:HOH679 3.6 28.6 1.0
O A:HOH727 3.6 39.9 1.0
O A:PHE120 3.6 25.2 1.0
CA A:HIS119 3.8 25.9 1.0
CG A:HIS119 4.0 42.1 1.0
C A:HIS119 4.0 25.4 1.0
CB A:PHE120 4.1 24.6 1.0
CE1 A:HIS119 4.1 42.5 1.0
CA A:PHE120 4.1 26.8 1.0
CD2 A:HIS12 4.2 19.8 1.0
CE1 A:HIS12 4.2 20.3 1.0
CB A:HIS119 4.3 32.6 1.0
C A:PHE120 4.3 29.4 1.0
NE2 A:GLN11 4.3 29.1 1.0
N2 A:CPT501 4.4 41.4 0.4
NE2 A:HIS119 5.0 45.2 1.0
CD2 A:HIS119 5.0 44.2 1.0

Chlorine binding site 2 out of 6 in 4rte

Go back to Chlorine Binding Sites List in 4rte
Chlorine binding site 2 out of 6 in the The X-Ray Structure of Bovine Pancreatic Ribonuclease Incubated in the Presence of An Excess of Cisplatin (1:10 Ratio)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of The X-Ray Structure of Bovine Pancreatic Ribonuclease Incubated in the Presence of An Excess of Cisplatin (1:10 Ratio) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl502

b:22.4
occ:0.20
CL1 A:CPT502 0.0 22.4 0.2
PT1 A:CPT502 2.3 46.9 0.2
CE1 A:HIS105 3.0 26.4 1.0
N1 A:CPT502 3.1 38.2 0.2
NE2 A:HIS105 3.2 29.7 1.0
O A:TYR76 3.9 22.3 1.0
O A:HOH661 4.2 25.7 1.0
ND1 A:HIS105 4.3 26.3 1.0
CG2 A:THR78 4.4 27.6 1.0
N2 A:CPT502 4.4 40.7 0.2
CD2 A:HIS105 4.5 23.6 1.0
N A:THR78 4.6 21.2 1.0
CA A:SER77 4.7 19.8 1.0
O A:HOH643 4.8 8.7 0.5
C A:SER77 4.9 19.6 1.0
C A:TYR76 5.0 20.2 1.0

Chlorine binding site 3 out of 6 in 4rte

Go back to Chlorine Binding Sites List in 4rte
Chlorine binding site 3 out of 6 in the The X-Ray Structure of Bovine Pancreatic Ribonuclease Incubated in the Presence of An Excess of Cisplatin (1:10 Ratio)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of The X-Ray Structure of Bovine Pancreatic Ribonuclease Incubated in the Presence of An Excess of Cisplatin (1:10 Ratio) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl503

b:31.8
occ:0.60
CL1 A:CPT503 0.0 31.8 0.6
PT1 A:CPT503 2.4 41.1 0.6
PT1 A:CPT504 2.4 42.5 0.4
OE1 A:GLN28 3.0 48.6 1.0
N1 A:CPT503 3.1 31.7 0.6
CG A:MET29 3.4 26.4 0.4
CB A:GLN28 3.4 30.2 1.0
CG A:MET29 3.4 20.7 0.6
SD A:MET29 3.5 21.4 0.6
O A:TYR25 3.8 21.3 1.0
SD A:MET29 3.9 28.8 0.4
CD A:GLN28 4.0 46.3 1.0
CD2 A:TYR25 4.0 22.8 1.0
N A:MET29 4.0 23.5 0.6
N A:MET29 4.0 25.3 0.4
CA A:TYR25 4.2 22.3 1.0
CG A:GLN28 4.3 36.5 1.0
C A:GLN28 4.4 25.4 1.0
CE2 A:TYR25 4.4 25.8 1.0
N2 A:CPT503 4.5 33.4 0.6
CA A:GLN28 4.5 26.7 1.0
C A:TYR25 4.5 21.9 1.0
CB A:MET29 4.5 26.2 0.4
CB A:MET29 4.6 21.7 0.6
CA A:MET29 4.6 24.6 0.4
CG A:TYR25 4.6 21.9 1.0
CA A:MET29 4.6 21.6 0.6
CB A:TYR25 4.9 20.1 1.0

Chlorine binding site 4 out of 6 in 4rte

Go back to Chlorine Binding Sites List in 4rte
Chlorine binding site 4 out of 6 in the The X-Ray Structure of Bovine Pancreatic Ribonuclease Incubated in the Presence of An Excess of Cisplatin (1:10 Ratio)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of The X-Ray Structure of Bovine Pancreatic Ribonuclease Incubated in the Presence of An Excess of Cisplatin (1:10 Ratio) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl505

b:33.4
occ:1.00
OG1 A:THR3 2.9 21.9 1.0
O A:HOH677 3.3 25.3 1.0
CB A:THR3 3.9 22.1 1.0
CB A:ALA5 4.0 22.8 1.0
O A:HOH686 4.0 27.9 1.0
CG2 A:THR3 4.0 23.0 1.0
N A:ALA6 4.1 18.7 1.0
CB A:ALA6 4.3 19.2 1.0
CA A:ALA6 4.7 19.2 1.0
C A:ALA5 4.8 22.0 1.0
O A:HOH678 4.8 24.9 1.0
CA A:ALA5 4.9 20.9 1.0

Chlorine binding site 5 out of 6 in 4rte

Go back to Chlorine Binding Sites List in 4rte
Chlorine binding site 5 out of 6 in the The X-Ray Structure of Bovine Pancreatic Ribonuclease Incubated in the Presence of An Excess of Cisplatin (1:10 Ratio)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of The X-Ray Structure of Bovine Pancreatic Ribonuclease Incubated in the Presence of An Excess of Cisplatin (1:10 Ratio) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl506

b:25.8
occ:1.00
N A:THR45 3.3 21.5 1.0
O A:HOH633 3.4 39.9 1.0
CE1 A:HIS12 3.5 20.3 1.0
CA A:ASN44 3.6 23.1 1.0
OG1 A:THR45 3.7 23.7 1.0
C A:ASN44 3.9 23.1 1.0
O A:HOH757 3.9 55.0 1.0
CD1 A:PHE120 4.0 23.3 1.0
CB A:THR45 4.0 22.2 1.0
ND1 A:HIS12 4.2 20.3 1.0
O A:VAL43 4.2 21.4 1.0
OD1 A:ASN44 4.2 22.6 1.0
CA A:THR45 4.2 21.4 1.0
N A:ASN44 4.3 22.4 1.0
NE2 A:HIS12 4.4 21.2 1.0
CB A:PHE120 4.4 24.6 1.0
CG A:PHE120 4.4 24.3 1.0
NZ A:LYS41 4.5 36.9 1.0
C A:VAL43 4.5 23.9 1.0
CG1 A:VAL43 4.6 26.9 1.0
O A:PHE120 4.7 25.2 1.0
CB A:ASN44 4.7 22.5 1.0
CG A:ASN44 4.7 22.8 1.0
CE1 A:PHE120 4.7 23.6 1.0
O A:THR45 4.9 20.9 1.0

Chlorine binding site 6 out of 6 in 4rte

Go back to Chlorine Binding Sites List in 4rte
Chlorine binding site 6 out of 6 in the The X-Ray Structure of Bovine Pancreatic Ribonuclease Incubated in the Presence of An Excess of Cisplatin (1:10 Ratio)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of The X-Ray Structure of Bovine Pancreatic Ribonuclease Incubated in the Presence of An Excess of Cisplatin (1:10 Ratio) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl507

b:21.1
occ:0.40
CL1 A:CPT501 1.0 36.3 0.4
PT1 A:CPT501 2.6 48.1 0.4
O A:HOH679 2.7 28.6 1.0
N1 A:CPT501 2.8 38.2 0.4
NE2 A:HIS12 2.9 21.2 1.0
O A:HOH757 2.9 55.0 1.0
N A:PHE120 3.2 23.7 1.0
CD2 A:HIS12 3.6 19.8 1.0
CA A:HIS119 3.6 25.9 1.0
O A:HOH727 3.7 39.9 1.0
O A:HOH633 3.7 39.9 1.0
NE2 A:GLN11 3.8 29.1 1.0
C A:HIS119 3.9 25.4 1.0
ND1 A:HIS119 3.9 48.5 1.0
CE1 A:HIS12 4.0 20.3 1.0
CB A:PHE120 4.1 24.6 1.0
CA A:PHE120 4.1 26.8 1.0
O A:PHE120 4.2 25.2 1.0
CB A:HIS119 4.3 32.6 1.0
CG A:HIS119 4.4 42.1 1.0
O A:VAL118 4.5 28.6 1.0
N2 A:CPT501 4.5 41.4 0.4
C A:PHE120 4.7 29.4 1.0
N A:HIS119 4.7 24.0 1.0
CD2 A:PHE8 4.8 20.4 1.0
CG A:HIS12 4.8 20.7 1.0
CE1 A:HIS119 4.8 42.5 1.0
ND1 A:HIS12 5.0 20.3 1.0

Reference:

D.Picone, F.Donnarumma, G.Ferraro, I.Russo Krauss, A.Fagagnini, G.Gotte, A.Merlino. Platinated Oligomers of Bovine Pancreatic Ribonuclease: Structure and Stability. J.Inorg.Biochem. V. 146 37 2015.
ISSN: ISSN 0162-0134
PubMed: 25756333
DOI: 10.1016/J.JINORGBIO.2015.02.011
Page generated: Fri Jul 11 21:34:43 2025

Last articles

Cl in 8BST
Cl in 8BT7
Cl in 8BTA
Cl in 8BT2
Cl in 8BSG
Cl in 8BT1
Cl in 8BSD
Cl in 8BSR
Cl in 8BRN
Cl in 8BS0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy