Chlorine in PDB 4wiq: The Structure of Murine Alpha-Dystroglycan T190M Mutant N-Terminal Domain.

The structure of The Structure of Murine Alpha-Dystroglycan T190M Mutant N-Terminal Domain., PDB code: 4wiq was solved by A.Brancaccio, D.Lamba, A.Cassetta, M.Bozzi, S.Covaceuszach, F.Sciandra, M.G.Bigotti, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.10 / 1.59
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	71.879, 71.879, 144.296, 90.00, 90.00, 120.00
R / Rfree (%)	14.6 / 16.3

The binding sites of Chlorine atom in the The Structure of Murine Alpha-Dystroglycan T190M Mutant N-Terminal Domain. (pdb code 4wiq). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the The Structure of Murine Alpha-Dystroglycan T190M Mutant N-Terminal Domain., PDB code: 4wiq:

Chlorine binding site 1 out of 1 in the The Structure of Murine Alpha-Dystroglycan T190M Mutant N-Terminal Domain.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The Structure of Murine Alpha-Dystroglycan T190M Mutant N-Terminal Domain. within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl404 b:73.7 occ:1.00 HZ3 A:LYS224 3.0 59.8 1.0 O A:HOH662 3.4 31.2 1.0 O A:HOH626 3.4 43.9 1.0 HG13 A:VAL226 3.7 28.6 1.0 O A:HOH674 3.7 42.1 1.0 HG13 A:VAL72 3.8 28.8 1.0 HE2 A:LYS224 3.8 50.1 1.0 NZ A:LYS224 3.8 49.8 1.0 HE3 A:LYS224 3.9 50.1 1.0 O A:HOH615 4.0 39.8 1.0 HG12 A:VAL226 4.0 28.6 1.0 HG21 A:VAL226 4.0 25.7 1.0 CE A:LYS224 4.1 41.7 1.0 HZ2 A:LYS224 4.3 59.8 1.0 HG3 A:GLU157 4.3 86.0 0.8 CG1 A:VAL226 4.3 23.9 1.0 HZ1 A:LYS224 4.4 59.8 1.0 O A:PRO156 4.5 31.2 1.0 HB A:VAL226 4.7 23.7 1.0 OE2 A:GLU157 4.7 65.0 1.0 CG1 A:VAL72 4.7 24.0 1.0 O A:HOH682 4.8 53.5 1.0 CG2 A:VAL226 4.9 21.4 1.0 O A:HOH602 4.9 29.5 1.0 CB A:VAL226 4.9 19.7 1.0 HA A:GLU157 5.0 78.7 0.8 HB A:VAL72 5.0 28.6 1.0

M.Bozzi, A.Cassetta, S.Covaceuszach, M.G.Bigotti, S.Bannister, W.Hubner, F.Sciandra, D.Lamba, A.Brancaccio. The Structure of the T190M Mutant of Murine Alpha-Dystroglycan at High Resolution: Insight Into the Molecular Basis of A Primary Dystroglycanopathy. Plos One V. 10 24277 2015.
ISSN: ESSN 1932-6203
PubMed: 25932631
DOI: 10.1371/JOURNAL.PONE.0124277