Atomistry » Chlorine » PDB 4wki-4ws4 » 4wp8
Atomistry »
  Chlorine »
    PDB 4wki-4ws4 »
      4wp8 »

Chlorine in PDB 4wp8: Crystal Structure of Adenylyl Cyclase MA1120 From Mycobacterium Avium in Complex with 2'5'-Dd-3'-Atp and Manganese Ion

Enzymatic activity of Crystal Structure of Adenylyl Cyclase MA1120 From Mycobacterium Avium in Complex with 2'5'-Dd-3'-Atp and Manganese Ion

All present enzymatic activity of Crystal Structure of Adenylyl Cyclase MA1120 From Mycobacterium Avium in Complex with 2'5'-Dd-3'-Atp and Manganese Ion:
4.6.1.1;

Protein crystallography data

The structure of Crystal Structure of Adenylyl Cyclase MA1120 From Mycobacterium Avium in Complex with 2'5'-Dd-3'-Atp and Manganese Ion, PDB code: 4wp8 was solved by D.V.Barathy, N.G.Bharambe, K.Suguna, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 55.96 / 1.65
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 51.970, 55.960, 54.070, 90.00, 106.35, 90.00
R / Rfree (%) 17.2 / 21.5

Other elements in 4wp8:

The structure of Crystal Structure of Adenylyl Cyclase MA1120 From Mycobacterium Avium in Complex with 2'5'-Dd-3'-Atp and Manganese Ion also contains other interesting chemical elements:

Manganese (Mn) 2 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of Adenylyl Cyclase MA1120 From Mycobacterium Avium in Complex with 2'5'-Dd-3'-Atp and Manganese Ion (pdb code 4wp8). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Adenylyl Cyclase MA1120 From Mycobacterium Avium in Complex with 2'5'-Dd-3'-Atp and Manganese Ion, PDB code: 4wp8:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in 4wp8

Go back to Chlorine Binding Sites List in 4wp8
Chlorine binding site 1 out of 2 in the Crystal Structure of Adenylyl Cyclase MA1120 From Mycobacterium Avium in Complex with 2'5'-Dd-3'-Atp and Manganese Ion


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Adenylyl Cyclase MA1120 From Mycobacterium Avium in Complex with 2'5'-Dd-3'-Atp and Manganese Ion within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl302

b:24.8
occ:1.00
 NE2 A:GLN172 3.2 26.4 1.0
NE A:ARG168 3.2 22.0 1.0
NH2 A:ARG168 3.3 24.6 1.0
N A:LYS205 3.3 20.4 1.0
CZ A:ARG168 3.7 24.1 1.0
CA A:LEU204 3.7 21.0 1.0
C A:LEU204 4.0 20.9 1.0
CD2 A:LEU204 4.0 21.6 1.0
CB A:ARG168 4.0 18.1 1.0
CB A:LYS205 4.1 21.9 1.0
CD A:GLN172 4.1 24.2 1.0
O A:GLU203 4.1 22.3 1.0
CG A:GLN172 4.2 21.8 1.0
CB A:LEU204 4.2 20.7 1.0
CA A:LYS205 4.3 20.7 1.0
CD A:ARG168 4.3 21.0 1.0
O A:ARG168 4.3 15.6 1.0
CG A:ARG168 4.4 19.7 1.0
O A:HOH444 4.7 36.8 1.0
CA A:ARG168 4.7 16.7 1.0
CG A:LEU204 4.8 20.9 1.0
N A:LEU204 4.8 21.2 1.0
C A:ARG168 4.9 15.7 1.0
C A:GLU203 4.9 21.8 1.0

Chlorine binding site 2 out of 2 in 4wp8

Go back to Chlorine Binding Sites List in 4wp8
Chlorine binding site 2 out of 2 in the Crystal Structure of Adenylyl Cyclase MA1120 From Mycobacterium Avium in Complex with 2'5'-Dd-3'-Atp and Manganese Ion


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Adenylyl Cyclase MA1120 From Mycobacterium Avium in Complex with 2'5'-Dd-3'-Atp and Manganese Ion within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl303

b:28.4
occ:1.00
 ND2 B:ASN133 3.3 20.7 1.0
NH2 B:ARG134 3.3 23.1 1.0
NH1 B:ARG129 3.9 29.4 1.0
NH1 B:ARG134 4.0 22.7 1.0
CZ B:ARG134 4.1 23.1 1.0
CG B:ARG130 4.2 27.2 1.0
CG B:ASN133 4.3 20.5 1.0
CB B:ASN133 4.3 19.5 1.0
CA B:ARG130 4.5 22.1 1.0
CB B:ARG130 4.7 24.5 1.0
NE B:ARG130 4.8 32.9 1.0

Reference:

D.V.Barathy, N.G.Bharambe, W.Syed, A.Zaveri, S.S.Visweswariah, M.Cola Sigmaf O, S.Misquith, K.Suguna. Autoinhibitory Mechanism and Activity-Related Structural Changes in A Mycobacterial Adenylyl Cyclase J.Struct.Biol. V. 190 304 2015.
ISSN: ESSN 1095-8657
PubMed: 25916753
DOI: 10.1016/J.JSB.2015.04.013
Page generated: Sat Dec 12 11:18:25 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy