Atomistry » Chlorine » PDB 4wxe-4x90 » 4x5t
Atomistry »
  Chlorine »
    PDB 4wxe-4x90 »
      4x5t »

Chlorine in PDB 4x5t: Alpha 1 Glycine Receptor Transmembrane Structure Fused to the Extracellular Domain of Glic

Protein crystallography data

The structure of Alpha 1 Glycine Receptor Transmembrane Structure Fused to the Extracellular Domain of Glic, PDB code: 4x5t was solved by L.Sauguet, P.J.Corringer, C.Huon, M.Delarue, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 25.00 / 3.50
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 118.894, 132.304, 190.517, 90.00, 90.00, 90.00
R / Rfree (%) 25.4 / 27

Other elements in 4x5t:

The structure of Alpha 1 Glycine Receptor Transmembrane Structure Fused to the Extracellular Domain of Glic also contains other interesting chemical elements:

Nickel (Ni) 6 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Alpha 1 Glycine Receptor Transmembrane Structure Fused to the Extracellular Domain of Glic (pdb code 4x5t). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 6 binding sites of Chlorine where determined in the Alpha 1 Glycine Receptor Transmembrane Structure Fused to the Extracellular Domain of Glic, PDB code: 4x5t:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6;

Chlorine binding site 1 out of 6 in 4x5t

Go back to Chlorine Binding Sites List in 4x5t
Chlorine binding site 1 out of 6 in the Alpha 1 Glycine Receptor Transmembrane Structure Fused to the Extracellular Domain of Glic


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Alpha 1 Glycine Receptor Transmembrane Structure Fused to the Extracellular Domain of Glic within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl502

b:0.0
occ:1.00
 N A:ARG85 3.3 0.6 1.0
NH1 A:ARG85 3.3 0.9 1.0
N A:PHE78 3.4 0.4 1.0
CD2 A:PHE78 3.5 0.9 1.0
CG A:ARG85 3.6 0.6 1.0
CB A:ARG85 3.8 0.7 1.0
CA A:ALA84 3.9 0.5 1.0
CB A:PHE78 3.9 0.5 1.0
CD A:ARG85 4.0 0.9 1.0
C A:ALA84 4.1 0.1 1.0
CA A:ARG77 4.2 0.9 1.0
CG A:PHE78 4.2 0.7 1.0
CA A:ARG85 4.2 0.0 1.0
CB A:ALA84 4.2 0.1 1.0
CG2 A:VAL81 4.2 0.5 1.0
C A:ARG77 4.2 0.0 1.0
CA A:PHE78 4.2 0.5 1.0
CZ A:ARG85 4.4 0.4 1.0
CE2 A:PHE78 4.5 0.3 1.0
NE A:ARG85 4.6 0.1 1.0
O A:PHE78 4.6 0.0 1.0
CB A:ARG77 4.6 0.8 1.0
CG A:ARG77 4.9 0.1 1.0
C A:PHE78 5.0 1.0 1.0

Chlorine binding site 2 out of 6 in 4x5t

Go back to Chlorine Binding Sites List in 4x5t
Chlorine binding site 2 out of 6 in the Alpha 1 Glycine Receptor Transmembrane Structure Fused to the Extracellular Domain of Glic


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Alpha 1 Glycine Receptor Transmembrane Structure Fused to the Extracellular Domain of Glic within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl502

b:0.1
occ:1.00
 O B:PRO74 3.2 0.6 1.0
NH2 B:ARG85 3.3 1.0 1.0
N B:ILE76 3.6 0.6 1.0
O B:ILE76 3.9 0.3 1.0
CB B:ILE76 4.2 0.0 1.0
C B:PRO74 4.3 0.8 1.0
CA B:GLU75 4.4 0.7 1.0
CG2 B:ILE73 4.4 0.4 1.0
CA B:ILE76 4.4 0.5 1.0
OE1 B:GLU104 4.4 0.0 1.0
CG1 B:ILE76 4.5 0.4 1.0
C B:GLU75 4.5 0.3 1.0
OH B:TYR102 4.5 0.8 1.0
CD1 B:LEU45 4.5 0.0 1.0
CZ B:ARG85 4.5 0.8 1.0
C B:ILE76 4.6 0.7 1.0
N B:GLU75 4.8 0.5 1.0
CZ B:TYR102 4.9 0.4 1.0

Chlorine binding site 3 out of 6 in 4x5t

Go back to Chlorine Binding Sites List in 4x5t
Chlorine binding site 3 out of 6 in the Alpha 1 Glycine Receptor Transmembrane Structure Fused to the Extracellular Domain of Glic


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Alpha 1 Glycine Receptor Transmembrane Structure Fused to the Extracellular Domain of Glic within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl503

b:0.0
occ:1.00
 NH1 B:ARG85 3.1 0.5 1.0
N B:ARG85 3.2 0.3 1.0
CG B:ARG85 3.4 0.2 1.0
CD2 B:PHE78 3.6 0.3 1.0
N B:PHE78 3.6 0.2 1.0
CB B:ARG85 3.7 0.6 1.0
CD B:ARG85 3.8 0.2 1.0
CA B:ALA84 3.9 0.2 1.0
CA B:ARG85 4.0 0.2 1.0
C B:ALA84 4.1 1.0 1.0
CB B:ALA84 4.1 0.7 1.0
CB B:PHE78 4.1 0.4 1.0
CZ B:ARG85 4.1 0.8 1.0
CA B:ARG77 4.3 0.7 1.0
CG B:PHE78 4.3 0.9 1.0
NE B:ARG85 4.4 0.9 1.0
C B:ARG77 4.4 0.7 1.0
CG2 B:VAL81 4.4 0.6 1.0
CE2 B:PHE78 4.4 0.3 1.0
CA B:PHE78 4.5 0.0 1.0
CB B:ARG77 4.8 0.9 1.0
O B:PHE78 4.9 1.0 1.0
O B:ILE76 5.0 0.3 1.0

Chlorine binding site 4 out of 6 in 4x5t

Go back to Chlorine Binding Sites List in 4x5t
Chlorine binding site 4 out of 6 in the Alpha 1 Glycine Receptor Transmembrane Structure Fused to the Extracellular Domain of Glic


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Alpha 1 Glycine Receptor Transmembrane Structure Fused to the Extracellular Domain of Glic within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl502

b:0.6
occ:1.00
 N C:ARG85 3.2 99.8 1.0
NH1 C:ARG85 3.4 92.4 1.0
N C:PHE78 3.5 94.1 1.0
CD2 C:PHE78 3.6 90.8 1.0
CG C:ARG85 3.6 94.7 1.0
CB C:ARG85 3.8 95.5 1.0
CA C:ALA84 3.9 0.8 1.0
CB C:PHE78 3.9 92.9 1.0
CD C:ARG85 4.0 92.6 1.0
C C:ALA84 4.1 0.5 1.0
CA C:ARG85 4.1 99.4 1.0
CG2 C:VAL81 4.2 98.9 1.0
CG C:PHE78 4.2 91.4 1.0
CB C:ALA84 4.2 0.2 1.0
CA C:ARG77 4.2 95.6 1.0
CA C:PHE78 4.3 94.4 1.0
C C:ARG77 4.3 95.0 1.0
CZ C:ARG85 4.4 93.0 1.0
CE2 C:PHE78 4.5 90.9 1.0
O C:PHE78 4.6 98.9 1.0
NE C:ARG85 4.6 93.2 1.0
CB C:ARG77 4.7 98.8 1.0
C C:PHE78 5.0 97.5 1.0
CG C:ARG77 5.0 0.9 1.0

Chlorine binding site 5 out of 6 in 4x5t

Go back to Chlorine Binding Sites List in 4x5t
Chlorine binding site 5 out of 6 in the Alpha 1 Glycine Receptor Transmembrane Structure Fused to the Extracellular Domain of Glic


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Alpha 1 Glycine Receptor Transmembrane Structure Fused to the Extracellular Domain of Glic within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl503

b:0.0
occ:1.00
 O C:PRO74 3.3 0.0 1.0
NH2 C:ARG85 3.3 94.5 1.0
N C:ILE76 3.6 0.9 1.0
O C:ILE76 3.9 95.2 1.0
CA C:GLU75 4.3 0.7 1.0
CB C:ILE76 4.4 98.9 1.0
C C:PRO74 4.4 0.1 1.0
OE1 C:GLU104 4.4 0.2 1.0
CA C:ILE76 4.4 99.0 1.0
CG2 C:ILE73 4.5 0.3 1.0
C C:GLU75 4.5 0.9 1.0
CZ C:ARG85 4.5 93.0 1.0
OH C:TYR102 4.5 0.8 1.0
CG1 C:ILE76 4.6 0.2 1.0
C C:ILE76 4.6 96.3 1.0
CD1 C:LEU45 4.7 0.8 1.0
N C:GLU75 4.8 0.1 1.0
CZ C:TYR102 4.9 0.2 1.0

Chlorine binding site 6 out of 6 in 4x5t

Go back to Chlorine Binding Sites List in 4x5t
Chlorine binding site 6 out of 6 in the Alpha 1 Glycine Receptor Transmembrane Structure Fused to the Extracellular Domain of Glic


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of Alpha 1 Glycine Receptor Transmembrane Structure Fused to the Extracellular Domain of Glic within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Cl502

b:0.0
occ:1.00
 N E:PHE78 3.3 0.9 1.0
N E:ARG85 3.4 0.8 1.0
NH1 E:ARG85 3.4 0.0 1.0
CD2 E:PHE78 3.4 1.0 1.0
CG E:ARG85 3.7 0.7 1.0
CB E:PHE78 3.7 0.2 1.0
CB E:ARG85 3.8 0.3 1.0
CG E:PHE78 4.0 0.6 1.0
CG2 E:VAL81 4.0 0.5 1.0
CA E:ALA84 4.0 0.4 1.0
CD E:ARG85 4.0 0.6 1.0
CA E:PHE78 4.1 0.6 1.0
C E:ARG77 4.2 0.7 1.0
CA E:ARG85 4.2 0.6 1.0
C E:ALA84 4.2 0.4 1.0
CA E:ARG77 4.2 0.8 1.0
CB E:ALA84 4.3 0.9 1.0
CE2 E:PHE78 4.4 0.7 1.0
O E:PHE78 4.4 0.5 1.0
CZ E:ARG85 4.4 0.2 1.0
NE E:ARG85 4.7 0.5 1.0
CB E:ARG77 4.7 0.3 1.0
C E:PHE78 4.8 0.2 1.0

Reference:

G.Moraga-Cid, L.Sauguet, C.Huon, L.Malherbe, C.Girard-Blanc, S.Petres, S.Murail, A.Taly, M.Baaden, M.Delarue, P.J.Corringer. Allosteric and Hyperekplexic Mutant Phenotypes Investigated on An Alpha 1 Glycine Receptor Transmembrane Structure Proc.Natl.Acad.Sci.Usa 2015.
ISSN: ESSN 1091-6490
DOI: 10.1073/PNAS.1417864112
Page generated: Fri Jul 26 03:14:53 2024

Last articles

Zn in 2YRC
Zn in 2YQP
Zn in 2YR2
Zn in 2YQL
Zn in 2YPT
Zn in 2YPA
Zn in 2YPU
Zn in 2YNW
Zn in 2YNT
Zn in 2YNV
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy