Chlorine in PDB 4x83: Crystal Structure of DSCAM1 Isoform 7.44, N-Terminal Four Ig Domains

The structure of Crystal Structure of DSCAM1 Isoform 7.44, N-Terminal Four Ig Domains, PDB code: 4x83 was solved by Q.Chen, Y.Yu, S.A.Li, L.Cheng, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.44 / 1.90
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	61.734, 88.248, 94.310, 98.18, 98.79, 90.11
R / Rfree (%)	19.3 / 23.5

The binding sites of Chlorine atom in the Crystal Structure of DSCAM1 Isoform 7.44, N-Terminal Four Ig Domains (pdb code 4x83). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of DSCAM1 Isoform 7.44, N-Terminal Four Ig Domains, PDB code: 4x83:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of DSCAM1 Isoform 7.44, N-Terminal Four Ig Domains


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of DSCAM1 Isoform 7.44, N-Terminal Four Ig Domains within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl404 b:22.3 occ:1.00 HH22 B:ARG53 2.4 24.1 1.0 H C:LEU194 2.4 20.7 1.0 HA C:ARG193 2.9 25.1 1.0 O B:HOH541 3.1 22.1 1.0 O C:HOH655 3.1 28.7 1.0 HH12 B:ARG53 3.2 19.5 1.0 NH2 B:ARG53 3.2 20.1 1.0 N C:LEU194 3.3 17.3 1.0 HG3 B:GLU74 3.3 26.4 1.0 HH12 B:ARG40 3.4 38.1 1.0 HH11 B:ARG40 3.5 38.1 1.0 HG2 C:ARG193 3.5 49.9 1.0 HG2 B:GLU74 3.6 26.4 1.0 HB3 C:LEU194 3.6 25.1 1.0 NH1 B:ARG40 3.7 31.8 1.0 HH21 B:ARG53 3.7 24.1 1.0 CA C:ARG193 3.8 20.9 1.0 NH1 B:ARG53 3.8 16.3 1.0 CG B:GLU74 3.9 22.0 1.0 CZ B:ARG53 4.0 19.0 1.0 HG21 B:VAL49 4.0 23.3 1.0 C C:ARG193 4.0 15.0 1.0 HG22 B:VAL75 4.1 27.4 1.0 HB3 C:ARG193 4.1 31.2 1.0 HB2 C:LEU194 4.2 25.1 1.0 CB C:LEU194 4.2 20.9 1.0 HG22 B:VAL49 4.2 23.3 1.0 O C:LEU194 4.2 16.6 1.0 CA C:LEU194 4.2 16.9 1.0 CB C:ARG193 4.3 26.0 1.0 CG C:ARG193 4.3 41.5 1.0 HB2 B:GLU74 4.4 29.9 1.0 CG2 B:VAL49 4.5 19.4 1.0 HG23 B:VAL75 4.5 27.4 1.0 O C:HOH502 4.5 34.8 1.0 O C:HOH682 4.5 18.9 1.0 HD3 C:ARG193 4.6 40.8 1.0 HH11 B:ARG53 4.6 19.5 1.0 HG23 B:VAL49 4.6 23.3 1.0 O C:THR192 4.6 20.7 1.0 O C:HOH691 4.7 28.3 1.0 O B:GLU74 4.7 21.2 1.0 C C:LEU194 4.7 15.8 1.0 CG2 B:VAL75 4.8 22.9 1.0 CB B:GLU74 4.8 24.9 1.0 HH21 C:ARG183 4.8 29.1 1.0 CZ B:ARG40 4.9 29.6 1.0 HD3 B:ARG40 4.9 32.3 1.0 N C:ARG193 4.9 22.1 1.0 OE2 B:GLU74 5.0 26.1 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of DSCAM1 Isoform 7.44, N-Terminal Four Ig Domains


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of DSCAM1 Isoform 7.44, N-Terminal Four Ig Domains within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl403 b:20.3 occ:1.00 HH22 C:ARG53 2.5 24.2 1.0 O C:HOH618 3.0 26.9 1.0 O C:HOH569 3.0 22.4 1.0 HH12 C:ARG53 3.2 20.4 1.0 HG3 C:GLU74 3.3 26.3 1.0 NH2 C:ARG53 3.3 20.2 1.0 HG2 C:GLU74 3.5 26.3 1.0 HH12 C:ARG40 3.6 43.3 1.0 HH11 C:ARG40 3.6 43.3 1.0 CG C:GLU74 3.8 21.9 1.0 HH21 C:ARG53 3.8 24.2 1.0 NH1 C:ARG40 3.9 36.0 1.0 NH1 C:ARG53 3.9 17.0 1.0 HG21 C:VAL49 3.9 20.7 1.0 CZ C:ARG53 4.0 15.4 1.0 HG22 C:VAL75 4.1 26.5 1.0 HG22 C:VAL49 4.2 20.7 1.0 HB2 C:GLU74 4.4 27.0 1.0 CG2 C:VAL49 4.4 17.3 1.0 HG23 C:VAL75 4.6 26.5 1.0 HG23 C:VAL49 4.6 20.7 1.0 O C:HOH714 4.6 18.3 1.0 HH11 C:ARG53 4.6 20.4 1.0 CB C:GLU74 4.7 22.5 1.0 CG2 C:VAL75 4.8 22.1 1.0 O C:GLU74 4.8 20.4 1.0 OE2 C:GLU74 4.8 25.5 1.0 CD C:GLU74 4.9 24.1 1.0 HD3 C:ARG40 5.0 35.6 1.0

S.A.Li, L.Cheng, Y.Yu, Q.Chen. Structural Basis of DSCAM1 Homodimerization: Insights Into Context Constraint For Protein Recognition Sci Adv V. 2 01118 2016.
ISSN: ESSN 2375-2548
PubMed: 27386517
DOI: 10.1126/SCIADV.1501118