Chlorine in PDB 4xfx: Structure of the Native Full-Length Hiv-1 Capsid Protein

The structure of Structure of the Native Full-Length Hiv-1 Capsid Protein, PDB code: 4xfx was solved by A.T.Gres, K.A.Kirby, S.G.Sarafianos, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.00 / 2.43
Space group	P 6
Cell size a, b, c (Å), α, β, γ (°)	92.328, 92.328, 57.340, 90.00, 90.00, 120.00
R / Rfree (%)	22.2 / 24.9

The structure of Structure of the Native Full-Length Hiv-1 Capsid Protein also contains other interesting chemical elements:

Iodine

(I)

7 atoms

The binding sites of Chlorine atom in the Structure of the Native Full-Length Hiv-1 Capsid Protein (pdb code 4xfx). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structure of the Native Full-Length Hiv-1 Capsid Protein, PDB code: 4xfx:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Structure of the Native Full-Length Hiv-1 Capsid Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of the Native Full-Length Hiv-1 Capsid Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl308 b:44.6 occ:1.00 CG A:ASN57 3.6 25.9 1.0 CB A:ASN57 3.7 23.9 1.0 ND2 A:ASN57 3.7 25.4 1.0 OD1 A:ASN57 3.9 23.3 1.0 CA A:ASN57 4.7 22.0 1.0 O A:ASN57 4.9 17.6 1.0 O A:HOH424 4.9 34.3 1.0

Chlorine binding site 2 out of 2 in the Structure of the Native Full-Length Hiv-1 Capsid Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of the Native Full-Length Hiv-1 Capsid Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl309 b:52.9 occ:1.00 O A:HOH452 3.5 33.6 1.0 CG2 A:ILE124 3.9 73.7 1.0 O A:HOH465 4.1 39.3 1.0 CD A:PRO125 4.2 48.1 1.0 CA A:ILE124 4.2 66.9 1.0 CH2 A:TRP80 4.4 38.6 1.0 CB A:ILE124 4.5 71.2 1.0 CD1 A:ILE129 4.6 42.8 1.0 O A:PRO123 4.6 77.1 1.0 CG1 A:ILE124 4.6 79.3 1.0 N A:PRO125 4.9 47.8 1.0 C A:ILE124 4.9 57.6 1.0

A.T.Gres, K.A.Kirby, V.N.Kewalramani, J.J.Tanner, O.Pornillos, S.G.Sarafianos. Structural Virology. X-Ray Crystal Structures of Native Hiv-1 Capsid Protein Reveal Conformational Variability. Science V. 349 99 2015.
ISSN: ESSN 1095-9203
PubMed: 26044298
DOI: 10.1126/SCIENCE.AAA5936