Chlorine in PDB 4xhv: Crystal Structure of Drosophila Spinophilin-Pdz and A C-Terminal Peptide of Neurexin

The structure of Crystal Structure of Drosophila Spinophilin-Pdz and A C-Terminal Peptide of Neurexin, PDB code: 4xhv was solved by J.H.Driller, K.G.H.Muhammad, S.Reddy, U.Rey, M.A.Boehme, C.Hollmann, N.Ramesh, H.Depner, J.Luetzkendorf, T.Matkovic, D.Bergeron, C.Quentin, J.Schmoranzer, F.Goettfert, M.Holt, M.C.Wahl, S.W.Hell, A.Walter, S.J.Sigrist, B.Loll, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	32.03 / 1.23
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	45.302, 45.302, 94.533, 90.00, 90.00, 90.00
R / Rfree (%)	13.8 / 16.2

The structure of Crystal Structure of Drosophila Spinophilin-Pdz and A C-Terminal Peptide of Neurexin also contains other interesting chemical elements:

Zinc

(Zn)

1 atom

The binding sites of Chlorine atom in the Crystal Structure of Drosophila Spinophilin-Pdz and A C-Terminal Peptide of Neurexin (pdb code 4xhv). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Drosophila Spinophilin-Pdz and A C-Terminal Peptide of Neurexin, PDB code: 4xhv:

Chlorine binding site 1 out of 1 in the Crystal Structure of Drosophila Spinophilin-Pdz and A C-Terminal Peptide of Neurexin


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Drosophila Spinophilin-Pdz and A C-Terminal Peptide of Neurexin within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1402 b:15.8 occ:1.00 H A:ILE1291 2.1 7.5 1.0 HE21 A:GLN1313 2.2 8.3 1.0 O A:LEU1322 2.8 7.5 1.0 O A:ILE1314 2.8 6.9 1.0 HA2 A:GLY1290 2.8 9.5 1.0 HA A:ILE1315 2.9 8.8 1.0 N A:ILE1291 3.0 6.3 1.0 NE2 A:GLN1313 3.0 6.9 1.0 HG2 A:GLN1313 3.1 8.0 1.0 HB A:ILE1291 3.2 8.5 1.0 HG3 A:GLN1313 3.3 8.0 1.0 HG22 A:VAL1323 3.4 14.0 1.0 HB2 A:LEU1322 3.5 8.8 1.0 CA A:GLY1290 3.5 8.0 1.0 CG A:GLN1313 3.5 6.7 1.0 C A:LEU1322 3.5 7.4 1.0 HE22 A:GLN1313 3.6 8.3 1.0 HA3 A:GLY1290 3.6 9.5 1.0 C A:ILE1314 3.7 6.3 1.0 O A:ILE1291 3.7 7.3 1.0 C A:GLY1290 3.7 7.2 1.0 HA A:VAL1323 3.7 10.0 1.0 CD A:GLN1313 3.8 6.2 1.0 HG23 A:VAL1323 3.8 14.0 1.0 HG12 A:ILE1291 3.8 8.4 1.0 CA A:ILE1315 3.8 7.4 1.0 CA A:ILE1291 3.9 6.4 1.0 CB A:ILE1291 3.9 7.1 1.0 HB3 A:LEU1322 4.0 8.8 1.0 CG2 A:VAL1323 4.0 11.6 1.0 CB A:LEU1322 4.1 7.3 1.0 N A:ILE1315 4.1 7.0 1.0 N A:VAL1323 4.2 7.8 1.0 C A:ILE1291 4.3 6.4 1.0 CG1 A:ILE1291 4.3 7.0 1.0 O A:ILE1315 4.3 8.5 1.0 CA A:VAL1323 4.4 8.3 1.0 HG12 A:ILE1315 4.4 9.1 1.0 CA A:LEU1322 4.4 7.6 1.0 C A:ILE1315 4.5 7.3 1.0 H A:ILE1314 4.5 8.0 1.0 HG23 A:ILE1315 4.6 10.8 1.0 HG13 A:ILE1291 4.6 8.4 1.0 N A:ILE1314 4.7 6.7 1.0 O A:LEU1289 4.7 8.7 1.0 HA A:ILE1291 4.7 7.6 1.0 H A:LEU1322 4.8 9.8 1.0 HG21 A:VAL1323 4.8 14.0 1.0 N A:GLY1290 4.8 7.7 1.0 CA A:ILE1314 4.8 6.4 1.0 CB A:ILE1315 4.8 7.1 1.0 HG13 A:ILE1315 4.9 9.1 1.0 CB A:VAL1323 4.9 10.1 1.0 H A:VAL1323 4.9 9.3 1.0 CG1 A:ILE1315 4.9 7.6 1.0 O A:GLY1290 4.9 8.2 1.0 H A:ILE1315 4.9 8.3 0.9 CB A:GLN1313 5.0 6.6 1.0 OE1 A:GLN1313 5.0 7.3 1.0

K.Muhammad, S.Reddy-Alla, J.H.Driller, D.Schreiner, U.Rey, M.A.Bohme, C.Hollmann, N.Ramesh, H.Depner, J.Lutzkendorf, T.Matkovic, T.Gotz, D.D.Bergeron, J.Schmoranzer, F.Goettfert, M.Holt, M.C.Wahl, S.W.Hell, P.Scheiffele, A.M.Walter, B.Loll, S.J.Sigrist. Presynaptic Spinophilin Tunes Neurexin Signalling to Control Active Zone Architecture and Function. Nat Commun V. 6 8362 2015.
ISSN: ESSN 2041-1723
PubMed: 26471740
DOI: 10.1038/NCOMMS9362