Chlorine in PDB 4xos: ANP32A Lrr Domain

The structure of ANP32A Lrr Domain, PDB code: 4xos was solved by S.Zamora-Caballero, J.Bravo, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.09 / 1.56
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	48.040, 50.880, 63.020, 90.00, 110.19, 90.00
R / Rfree (%)	16 / 19.3

The binding sites of Chlorine atom in the ANP32A Lrr Domain (pdb code 4xos). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the ANP32A Lrr Domain, PDB code: 4xos:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the ANP32A Lrr Domain


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of ANP32A Lrr Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl201 b:24.5 occ:1.00 H A:LYS20 2.3 16.6 1.0 HH12 A:ARG14 2.6 29.6 1.0 H A:GLU21 2.7 16.6 1.0 O A:HOH383 3.1 32.7 1.0 N A:LYS20 3.1 13.8 1.0 HB2 A:LYS20 3.2 21.3 1.0 HA A:VAL19 3.3 19.7 1.0 O A:HOH317 3.4 32.8 1.0 NH1 A:ARG14 3.5 24.6 1.0 HG1 B:THR55 3.5 31.1 1.0 HB B:THR55 3.5 32.3 1.0 HG13 A:VAL19 3.5 23.2 1.0 N A:GLU21 3.5 13.8 1.0 HH22 A:ARG14 3.8 33.9 1.0 HH11 A:ARG14 3.9 29.6 1.0 O A:GLU21 3.9 18.6 1.0 CB A:LYS20 3.9 17.8 1.0 CA A:LYS20 3.9 12.7 1.0 HG2 A:LYS20 4.0 26.1 1.0 OG1 B:THR55 4.0 25.9 1.0 CA A:VAL19 4.1 16.4 1.0 C A:VAL19 4.1 16.8 1.0 HB2 A:GLU21 4.1 23.1 1.0 HG21 B:THR55 4.1 37.0 1.0 CB B:THR55 4.2 26.9 1.0 C A:LYS20 4.3 14.2 1.0 HG12 A:VAL19 4.3 23.2 1.0 CG1 A:VAL19 4.3 19.3 1.0 CZ A:ARG14 4.4 24.3 1.0 NH2 A:ARG14 4.4 28.2 1.0 CG A:LYS20 4.4 21.8 1.0 CA A:GLU21 4.5 14.6 1.0 HG3 A:GLU21 4.5 46.1 1.0 C A:GLU21 4.6 15.4 1.0 O A:ASP18 4.6 26.9 1.0 CG2 B:THR55 4.7 30.8 1.0 O B:HOH334 4.7 31.9 1.0 HB3 A:LYS20 4.7 21.3 1.0 CB A:GLU21 4.7 19.2 1.0 HG3 A:LYS20 4.7 26.1 1.0 CB A:VAL19 4.8 19.3 1.0 HA A:LYS20 4.8 15.2 1.0 HG22 A:VAL19 4.8 25.9 1.0

Chlorine binding site 2 out of 2 in the ANP32A Lrr Domain


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of ANP32A Lrr Domain within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl202 b:30.2 occ:1.00 H B:LYS20 2.3 22.6 1.0 H B:GLU21 2.6 18.0 1.0 HH12 B:ARG14 2.7 28.5 1.0 N B:LYS20 3.2 18.8 1.0 HA B:VAL19 3.2 20.5 1.0 HB2 B:LYS20 3.3 28.7 1.0 N B:GLU21 3.4 15.0 1.0 NH1 B:ARG14 3.4 23.8 1.0 HH11 B:ARG14 3.5 28.5 1.0 HB2 B:GLU21 3.7 30.6 1.0 HG13 B:VAL19 3.8 27.5 1.0 O B:GLU21 3.8 17.7 1.0 CA B:LYS20 3.9 18.8 1.0 O B:HOH359 4.0 36.9 1.0 CA B:VAL19 4.0 17.1 1.0 CB B:LYS20 4.0 23.9 1.0 C B:VAL19 4.1 22.1 1.0 O B:HOH322 4.1 34.1 1.0 HG3 B:LYS20 4.1 43.0 1.0 O B:ASP18 4.1 30.7 1.0 C B:LYS20 4.1 15.0 1.0 HG3 B:GLU21 4.2 62.4 1.0 CA B:GLU21 4.3 15.6 1.0 CB B:GLU21 4.4 25.5 1.0 HG12 B:VAL19 4.4 27.5 1.0 CG1 B:VAL19 4.4 22.9 1.0 C B:GLU21 4.5 17.1 1.0 HH22 B:ARG14 4.5 37.7 1.0 CG B:LYS20 4.6 35.9 1.0 CZ B:ARG14 4.6 27.2 1.0 CG B:GLU21 4.8 52.0 1.0 HB3 B:LYS20 4.8 28.7 1.0 CB B:VAL19 4.8 18.0 1.0 HA B:LYS20 4.8 22.6 1.0 NH2 B:ARG14 5.0 31.4 1.0 C B:ASP18 5.0 27.1 1.0

S.Zamora-Caballero, L.Siauciunaite-Gaubard, J.Bravo. High-Resolution Crystal Structure of the Leucine-Rich Repeat Domain of the Human Tumour Suppressor PP32A (ANP32A). Acta Crystallogr.,Sect.F V. 71 684 2015.
ISSN: ESSN 2053-230X
PubMed: 26057796
DOI: 10.1107/S2053230X15006457