Atomistry » Chlorine » PDB 4y8c-4ydj » 4y9b
Atomistry »
  Chlorine »
    PDB 4y8c-4ydj »
      4y9b »

Chlorine in PDB 4y9b: Crystal Structure of V30M Mutated Transthyretin in Complex with Alpha- Mangostin

Protein crystallography data

The structure of Crystal Structure of V30M Mutated Transthyretin in Complex with Alpha- Mangostin, PDB code: 4y9b was solved by T.Yokoyama, M.Mizuguchi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 27.60 / 1.40
Space group P 21 21 2
Cell size a, b, c (Å), α, β, γ (°) 43.633, 85.365, 64.703, 90.00, 90.00, 90.00
R / Rfree (%) 19.2 / 23.5

Other elements in 4y9b:

The structure of Crystal Structure of V30M Mutated Transthyretin in Complex with Alpha- Mangostin also contains other interesting chemical elements:

Calcium (Ca) 1 atom

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of V30M Mutated Transthyretin in Complex with Alpha- Mangostin (pdb code 4y9b). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of V30M Mutated Transthyretin in Complex with Alpha- Mangostin, PDB code: 4y9b:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in 4y9b

Go back to Chlorine Binding Sites List in 4y9b
Chlorine binding site 1 out of 2 in the Crystal Structure of V30M Mutated Transthyretin in Complex with Alpha- Mangostin


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of V30M Mutated Transthyretin in Complex with Alpha- Mangostin within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl201

b:37.9
occ:0.50
CE A:LYS15 3.8 25.2 1.0
CAM A:MKS200 3.8 16.7 0.5
NZ A:LYS15 4.3 30.0 1.0
CD1 A:LEU17 4.3 13.1 1.0
OAH A:MKS200 4.5 16.7 0.5
CAU A:MKS200 4.6 15.9 0.5
OAQ A:MKS200 4.6 16.7 0.5
CBB A:MKS200 4.8 16.4 0.5
CG A:LEU17 5.0 11.9 1.0

Chlorine binding site 2 out of 2 in 4y9b

Go back to Chlorine Binding Sites List in 4y9b
Chlorine binding site 2 out of 2 in the Crystal Structure of V30M Mutated Transthyretin in Complex with Alpha- Mangostin


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of V30M Mutated Transthyretin in Complex with Alpha- Mangostin within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl201

b:39.3
occ:0.50
CAM B:MKS200 3.6 16.6 0.5
CG2 B:THR106 4.0 18.8 1.0
CG2 B:VAL121 4.1 15.5 1.0
CB B:VAL121 4.3 13.9 1.0
CB B:THR106 4.3 15.5 1.0
OAH B:MKS200 4.4 15.8 0.5
OAQ B:MKS200 4.4 16.6 0.5
CAU B:MKS200 4.5 16.1 0.5
CBB B:MKS200 4.6 16.2 0.5
CG1 B:VAL121 4.6 15.1 1.0
OG1 B:THR106 4.8 18.7 1.0

Reference:

T.Yokoyama, M.Ueda, Y.Ando, M.Mizuguchi. Discovery of Gamma-Mangostin As An Amyloidogenesis Inhibitor Sci Rep V. 5 13570 2015.
ISSN: ESSN 2045-2322
PubMed: 26310724
DOI: 10.1038/SREP13570
Page generated: Sat Dec 12 11:24:28 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy