Chlorine in PDB 4yvd: Crytsal Structure of Human Pleiotropic Regulator 1 (PRL1)

Protein crystallography data

The structure of Crytsal Structure of Human Pleiotropic Regulator 1 (PRL1), PDB code: 4yvd was solved by A.Dong, H.Zeng, C.Xu, W.Tempel, Y.Li, H.He, C.Bountra, C.H.Arrowsmith, A.M.Edwards, P.J.Brown, J.Min, H.Wu, Structural Genomics Consortium(Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 41.55 / 1.70
Space group P 21 21 2
Cell size a, b, c (Å), α, β, γ (°) 158.330, 34.185, 48.818, 90.00, 90.00, 90.00
R / Rfree (%) 18.7 / 22

Other elements in 4yvd:

The structure of Crytsal Structure of Human Pleiotropic Regulator 1 (PRL1) also contains other interesting chemical elements:

Sodium (Na) 1 atom

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crytsal Structure of Human Pleiotropic Regulator 1 (PRL1) (pdb code 4yvd). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 5 binding sites of Chlorine where determined in the Crytsal Structure of Human Pleiotropic Regulator 1 (PRL1), PDB code: 4yvd:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5;

Chlorine binding site 1 out of 5 in 4yvd

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Chlorine binding site 1 out of 5 in the Crytsal Structure of Human Pleiotropic Regulator 1 (PRL1)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crytsal Structure of Human Pleiotropic Regulator 1 (PRL1) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl602

b:44.1
occ:1.00
O A:HOH814 3.0 51.4 1.0
N A:ASN408 3.2 25.4 1.0
O A:HOH828 3.6 51.9 1.0
CA A:GLN407 3.7 24.1 1.0
CB A:GLN407 3.8 24.9 1.0
C A:GLN407 3.9 27.2 1.0
CB A:ASN408 4.0 29.5 1.0
ND2 A:ASN408 4.1 33.5 1.0
UNK A:UNX608 4.1 30.0 1.0
CA A:ASN408 4.2 25.6 1.0
CG A:ASN408 4.3 41.3 1.0
O A:ASN408 4.4 27.9 1.0
CZ A:PHE405 4.4 31.5 1.0
CE2 A:PHE405 4.5 33.9 1.0
C A:ASN408 4.8 28.9 1.0
N A:GLN407 5.0 23.8 1.0
O A:HOH716 5.0 36.0 1.0
O A:ILE406 5.0 27.8 1.0

Chlorine binding site 2 out of 5 in 4yvd

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Chlorine binding site 2 out of 5 in the Crytsal Structure of Human Pleiotropic Regulator 1 (PRL1)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crytsal Structure of Human Pleiotropic Regulator 1 (PRL1) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl603

b:40.5
occ:1.00
O A:HOH722 2.8 45.6 1.0
O A:HOH836 3.0 39.0 0.6
N A:HIS283 3.2 20.2 1.0
CD A:LYS320 3.5 43.2 1.0
CE A:LYS320 3.6 55.0 1.0
CA A:ARG282 3.6 19.7 0.5
CA A:ARG282 3.7 19.2 0.5
NH2 A:ARG282 3.7 31.7 0.5
C A:ARG282 3.9 22.9 0.5
C A:ARG282 3.9 23.0 0.5
NZ A:LYS320 3.9 67.5 1.0
CB A:HIS283 4.1 23.6 1.0
O A:ILE281 4.1 25.2 1.0
CA A:HIS283 4.2 21.2 1.0
NE A:ARG282 4.2 37.1 0.5
O A:HIS283 4.2 26.6 1.0
ND1 A:HIS283 4.2 31.3 1.0
CZ A:ARG282 4.3 47.7 0.5
CB A:ARG282 4.5 18.5 0.5
N A:ARG282 4.5 21.1 0.5
N A:ARG282 4.6 20.8 0.5
CG A:HIS283 4.7 28.6 1.0
CB A:ARG282 4.7 16.8 0.5
C A:HIS283 4.7 26.0 1.0
C A:ILE281 4.7 25.8 1.0
CG A:ARG282 4.7 26.5 0.5
O A:HOH836 4.7 36.5 0.5
O A:HOH815 4.7 48.7 1.0
CG A:LYS320 5.0 36.6 1.0

Chlorine binding site 3 out of 5 in 4yvd

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Chlorine binding site 3 out of 5 in the Crytsal Structure of Human Pleiotropic Regulator 1 (PRL1)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crytsal Structure of Human Pleiotropic Regulator 1 (PRL1) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl604

b:34.0
occ:1.00
O A:HOH826 2.9 44.7 1.0
O A:HOH821 2.9 27.2 1.0
N A:ALA340 3.1 22.4 1.0
CE1 A:HIS384 3.5 28.2 1.0
CA A:GLN339 3.7 18.3 1.0
CG A:PRO298 3.7 32.4 1.0
CB A:GLN339 3.8 19.6 1.0
ND1 A:HIS384 3.8 27.9 1.0
C A:GLN339 3.8 22.6 1.0
CB A:ALA340 3.9 26.4 1.0
CA A:ALA340 4.1 24.0 1.0
NE2 A:HIS384 4.2 29.4 1.0
UNK A:UNX609 4.3 30.0 1.0
CB A:PRO298 4.4 29.9 1.0
O A:HOH762 4.7 27.2 1.0
CG A:HIS384 4.7 26.8 1.0
O A:HOH843 4.7 39.6 1.0
N A:ALA341 4.9 26.4 1.0
CD2 A:HIS384 4.9 29.7 1.0
CD A:PRO298 4.9 27.3 1.0
O A:HOH789 5.0 33.6 1.0

Chlorine binding site 4 out of 5 in 4yvd

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Chlorine binding site 4 out of 5 in the Crytsal Structure of Human Pleiotropic Regulator 1 (PRL1)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crytsal Structure of Human Pleiotropic Regulator 1 (PRL1) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl605

b:59.0
occ:1.00
N A:ARG449 3.1 41.4 1.0
CA A:GLN448 3.7 38.0 1.0
O A:ARG449 3.8 49.9 1.0
C A:GLN448 3.9 41.5 1.0
O A:HOH800 4.1 42.5 1.0
CG A:GLN448 4.1 44.6 1.0
CA A:ARG449 4.1 41.8 1.0
O A:PHE447 4.3 42.5 1.0
CB A:ARG449 4.3 41.8 1.0
C A:ARG449 4.4 49.1 1.0
CB A:GLN448 4.4 38.9 1.0
N A:GLN448 4.7 36.6 1.0
C A:PHE447 4.9 40.4 1.0
CG A:ARG449 5.0 44.2 1.0

Chlorine binding site 5 out of 5 in 4yvd

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Chlorine binding site 5 out of 5 in the Crytsal Structure of Human Pleiotropic Regulator 1 (PRL1)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Crytsal Structure of Human Pleiotropic Regulator 1 (PRL1) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl606

b:44.6
occ:1.00
OG A:SER404 2.9 43.6 1.0
N A:ASP402 3.2 26.8 1.0
N A:SER404 3.5 24.1 1.0
CB A:ASP402 3.6 32.4 1.0
O A:LYS399 3.6 26.4 1.0
CA A:ASP402 3.6 27.9 1.0
CB A:SER404 3.6 30.1 1.0
N A:GLY403 3.7 25.7 1.0
C A:ASP402 3.8 30.2 1.0
O A:PHE400 3.9 26.7 1.0
N A:PRO401 3.9 25.6 1.0
CD A:PRO401 4.0 28.5 1.0
C A:PHE400 4.0 27.6 1.0
CB A:LYS399 4.1 23.6 1.0
C A:LYS399 4.1 25.2 1.0
CA A:SER404 4.2 24.8 1.0
C A:PRO401 4.4 28.0 1.0
CG A:ASP402 4.4 51.4 1.0
C A:GLY403 4.5 26.5 1.0
OD2 A:ASP402 4.6 59.8 1.0
CA A:GLY403 4.6 24.9 1.0
O A:ASP402 4.7 30.3 1.0
CA A:PRO401 4.7 24.6 1.0
N A:PHE400 4.7 21.8 1.0
CA A:PHE400 4.8 21.4 1.0
CA A:LYS399 4.8 19.6 1.0
CG A:PRO401 4.9 32.9 1.0

Reference:

H.Zeng, A.Dong, C.Xu, W.Tempel, Y.Li, H.He, C.Bountra, C.H.Arrowsmith, A.M.Edwards, P.J.Brown, J.Min, H.Wu, Structural Genomics Consortium (Sgc). Crytsal Structure of Human Pleiotropic Regulator 1 (PRL1). To Be Published.
Page generated: Sat Dec 12 11:26:27 2020

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