Chlorine in PDB 4z3u: Prv Nuclear Egress Complex

The structure of Prv Nuclear Egress Complex, PDB code: 4z3u was solved by J.M.Bigalke, E.E.Heldwein, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.91 / 2.71
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	125.456, 125.456, 109.235, 90.00, 90.00, 90.00
R / Rfree (%)	21.2 / 27.3

The structure of Prv Nuclear Egress Complex also contains other interesting chemical elements:

Zinc	(Zn)	2 atoms
Sodium	(Na)	1 atom

The binding sites of Chlorine atom in the Prv Nuclear Egress Complex (pdb code 4z3u). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 5 binding sites of Chlorine where determined in the Prv Nuclear Egress Complex, PDB code: 4z3u:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5;

Chlorine binding site 1 out of 5 in the Prv Nuclear Egress Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Prv Nuclear Egress Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl201 b:0.1 occ:1.00 CB A:HIS101 3.3 61.5 1.0 O C:ALA125 3.6 67.8 1.0 CG A:HIS101 3.6 74.7 1.0 O C:GLY126 3.9 65.9 1.0 ND1 A:HIS101 4.0 74.6 1.0 C C:GLY126 4.3 60.2 1.0 OE2 C:GLU100 4.3 0.9 1.0 CD2 A:HIS101 4.4 82.1 1.0 CA C:GLY126 4.5 61.8 1.0 CA A:HIS101 4.7 66.5 1.0 C C:ALA125 4.7 63.0 1.0 O A:HIS101 4.8 72.5 1.0 CE1 A:HIS101 4.8 75.6 1.0 N C:GLY127 5.0 59.4 1.0 OG1 A:THR98 5.0 78.1 1.0

Chlorine binding site 2 out of 5 in the Prv Nuclear Egress Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Prv Nuclear Egress Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl302 b:77.1 occ:1.00 NE2 B:HIS209 3.4 59.0 1.0 CB B:VAL207 3.7 43.9 1.0 CG2 B:VAL207 3.8 46.2 1.0 CG1 B:VAL218 3.9 46.7 1.0 CD B:ARG220 4.0 82.3 1.0 CB B:PRO268 4.1 63.4 1.0 CE1 B:HIS209 4.2 65.6 1.0 NH1 B:ARG220 4.2 89.8 1.0 CG1 B:VAL207 4.2 45.4 1.0 CB B:VAL218 4.3 53.3 1.0 CD B:PRO269 4.4 73.9 1.0 O B:PRO269 4.5 77.3 1.0 CD2 B:HIS209 4.5 52.5 1.0 CG B:PRO269 4.6 79.4 1.0 CG B:ARG220 4.9 74.8 1.0 N B:PRO269 4.9 89.5 1.0 CG2 B:VAL218 5.0 57.4 1.0

Chlorine binding site 3 out of 5 in the Prv Nuclear Egress Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Prv Nuclear Egress Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl303 b:89.0 occ:1.00 O B:HOH407 2.8 50.2 1.0 ND1 B:HIS209 2.9 61.5 1.0 CE1 B:HIS209 3.6 65.6 1.0 NH2 C:ARG131 3.6 76.4 1.0 CG B:PRO62 3.7 51.6 1.0 CG B:HIS209 4.0 54.4 1.0 NH1 C:ARG131 4.1 81.0 1.0 CE1 B:PHE266 4.3 56.9 1.0 CZ C:ARG131 4.3 73.3 1.0 CB B:HIS209 4.4 52.9 1.0 CD B:PRO62 4.6 55.8 1.0 O B:VAL210 4.6 51.6 1.0 CB B:PRO62 4.7 42.6 1.0 CZ B:PHE266 4.7 56.8 1.0 NH1 C:ARG134 4.7 88.3 1.0 CD B:PRO269 4.8 73.9 1.0 NE2 B:HIS209 4.8 59.0 1.0

Chlorine binding site 4 out of 5 in the Prv Nuclear Egress Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Prv Nuclear Egress Complex within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl202 b:0.8 occ:1.00 ND1 C:HIS101 2.8 95.3 1.0 CE1 C:HIS101 2.9 96.4 1.0 O C:GLU100 3.3 99.6 1.0 O D:PRO58 3.4 45.5 1.0 CB D:ALA57 3.7 36.0 1.0 C C:GLU100 3.7 0.7 1.0 CG C:HIS101 4.2 88.4 1.0 OE2 A:GLU100 4.2 79.2 1.0 NE2 C:HIS101 4.2 95.2 1.0 CB C:GLU100 4.3 0.2 1.0 CA C:GLU100 4.3 0.8 1.0 NA C:NA201 4.3 82.7 1.0 CG A:GLU100 4.4 84.1 1.0 N C:HIS101 4.4 88.1 1.0 CD A:GLU100 4.4 80.0 1.0 C D:PRO58 4.5 45.9 1.0 C D:ALA57 4.6 46.1 1.0 N D:PRO58 4.7 50.1 1.0 CA C:HIS101 4.7 64.5 1.0 CA D:ALA57 4.7 37.1 1.0 CG1 D:VAL59 4.7 41.3 1.0 CD2 C:HIS101 4.8 93.5 1.0 O D:ALA57 4.9 47.1 1.0

Chlorine binding site 5 out of 5 in the Prv Nuclear Egress Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Prv Nuclear Egress Complex within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl302 b:79.5 occ:1.00 NE2 D:HIS209 3.3 56.0 1.0 CB D:VAL207 3.6 47.9 1.0 CG2 D:VAL207 3.7 41.8 1.0 CG1 D:VAL207 4.0 40.8 1.0 CD D:ARG220 4.0 80.8 1.0 CE1 D:HIS209 4.1 57.9 1.0 CG1 D:VAL218 4.2 39.3 1.0 CD D:PRO269 4.2 64.5 1.0 CB D:PRO268 4.2 50.6 1.0 CG D:PRO269 4.3 61.1 1.0 CD2 D:HIS209 4.3 51.2 1.0 NH1 D:ARG220 4.3 70.6 1.0 CB D:VAL218 4.4 39.6 1.0 O D:PRO269 4.6 72.6 1.0 N D:PRO269 4.8 69.6 1.0 CG D:ARG220 4.9 67.5 1.0 CA D:VAL207 5.0 39.1 1.0

J.M.Bigalke, E.E.Heldwein. Structural Basis of Membrane Budding By the Nuclear Egress Complex of Herpesviruses. Embo J. V. 34 2921 2015.
ISSN: ESSN 1460-2075
PubMed: 26511020
DOI: 10.15252/EMBJ.201592359