Chlorine in PDB 4z7q: Integrin ALPHAIIBBETA3 in Complex with Agdv-NH2 Peptide

The structure of Integrin ALPHAIIBBETA3 in Complex with Agdv-NH2 Peptide, PDB code: 4z7q was solved by F.-Y.Lin, J.Zhu, T.A.Springer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.94 / 2.70
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	259.440, 144.240, 104.500, 90.00, 90.00, 90.00
R / Rfree (%)	18.8 / 23.6

The structure of Integrin ALPHAIIBBETA3 in Complex with Agdv-NH2 Peptide also contains other interesting chemical elements:

Manganese	(Mn)	6 atoms
Calcium	(Ca)	8 atoms

The binding sites of Chlorine atom in the Integrin ALPHAIIBBETA3 in Complex with Agdv-NH2 Peptide (pdb code 4z7q). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Integrin ALPHAIIBBETA3 in Complex with Agdv-NH2 Peptide, PDB code: 4z7q:

Chlorine binding site 1 out of 1 in the Integrin ALPHAIIBBETA3 in Complex with Agdv-NH2 Peptide


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Integrin ALPHAIIBBETA3 in Complex with Agdv-NH2 Peptide within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl509 b:0.3 occ:1.00 HE22 C:GLN444 3.0 90.2 1.0 OE1 C:GLN444 3.5 76.5 1.0 HE1 C:PHE411 3.7 48.5 1.0 NE2 C:GLN444 3.7 75.1 1.0 HD1 C:PHE411 4.0 47.1 1.0 CD C:GLN444 4.0 65.6 1.0 CE1 C:PHE411 4.3 40.4 1.0 CD1 C:PHE411 4.4 39.2 1.0 HE21 C:GLN444 4.5 90.2 1.0 CD1 C:PHE10 4.6 58.9 1.0 CG C:PHE10 4.7 46.5 1.0 HB3 C:PHE10 4.7 53.9 1.0 CE1 C:PHE10 4.8 68.5 1.0 CD2 C:PHE10 4.8 49.6 1.0 HD1 C:PHE10 4.9 70.7 1.0

F.Y.Lin, J.Zhu, E.T.Eng, N.E.Hudson, T.A.Springer. Beta-Subunit Binding Is Sufficient For Ligands to Open the Integrin Alpha Iib Beta 3 Headpiece. J.Biol.Chem. V. 291 4537 2016.
ISSN: ESSN 1083-351X
PubMed: 26631735
DOI: 10.1074/JBC.M115.705624