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Atomistry » Chlorine » PDB 4z6t-4zfz » 4zdy | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 4z6t-4zfz » 4zdy » |
Chlorine in PDB 4zdy: Saccharomyces Cerevisiae CYP51 (Lanosterol 14-Alpha Demethylase) Y140F Mutant Complexed with ItraconazoleProtein crystallography data
The structure of Saccharomyces Cerevisiae CYP51 (Lanosterol 14-Alpha Demethylase) Y140F Mutant Complexed with Itraconazole, PDB code: 4zdy
was solved by
A.Sagatova,
M.V.Keniya,
R.K.Wilson,
J.D.A.Tyndall,
B.C.Monk,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4zdy:
The structure of Saccharomyces Cerevisiae CYP51 (Lanosterol 14-Alpha Demethylase) Y140F Mutant Complexed with Itraconazole also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Saccharomyces Cerevisiae CYP51 (Lanosterol 14-Alpha Demethylase) Y140F Mutant Complexed with Itraconazole
(pdb code 4zdy). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Saccharomyces Cerevisiae CYP51 (Lanosterol 14-Alpha Demethylase) Y140F Mutant Complexed with Itraconazole, PDB code: 4zdy: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 4zdyGo back to Chlorine Binding Sites List in 4zdy
Chlorine binding site 1 out
of 2 in the Saccharomyces Cerevisiae CYP51 (Lanosterol 14-Alpha Demethylase) Y140F Mutant Complexed with Itraconazole
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 4zdyGo back to Chlorine Binding Sites List in 4zdy
Chlorine binding site 2 out
of 2 in the Saccharomyces Cerevisiae CYP51 (Lanosterol 14-Alpha Demethylase) Y140F Mutant Complexed with Itraconazole
Mono view Stereo pair view
Reference:
A.A.Sagatova,
M.V.Keniya,
R.K.Wilson,
M.Sabherwal,
J.D.Tyndall,
B.C.Monk.
Triazole Resistance Mediated By Mutations of A Conserved Active Site Tyrosine in Fungal Lanosterol 14 Alpha-Demethylase. Sci Rep V. 6 26213 2016.
Page generated: Sat Dec 12 11:27:53 2020
ISSN: ESSN 2045-2322 PubMed: 27188873 DOI: 10.1038/SREP26213 |
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