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Atomistry » Chlorine » PDB 4zyb-5a95 » 4zzn » |
Chlorine in PDB 4zzn: Human ERK2 in Complex with An InhibitorEnzymatic activity of Human ERK2 in Complex with An Inhibitor
All present enzymatic activity of Human ERK2 in Complex with An Inhibitor:
2.7.11.24; Protein crystallography data
The structure of Human ERK2 in Complex with An Inhibitor, PDB code: 4zzn
was solved by
R.A.Ward,
N.Colclough,
M.Challinor,
J.E.Debreczeni,
K.Eckersley,
G.Fairley,
L.Feron,
V.Flemington,
M.A.Graham,
R.Greenwood,
P.Hopcroft,
T.D.Howard,
M.James,
C.D.Jones,
C.R.Jones,
J.Renshaw,
K.Roberts,
L.Snow,
M.Tonge,
K.Yeung,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Human ERK2 in Complex with An Inhibitor
(pdb code 4zzn). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Human ERK2 in Complex with An Inhibitor, PDB code: 4zzn: Chlorine binding site 1 out of 1 in 4zznGo back to Chlorine Binding Sites List in 4zzn
Chlorine binding site 1 out
of 1 in the Human ERK2 in Complex with An Inhibitor
Mono view Stereo pair view
Reference:
R.A.Ward,
N.Colclough,
M.Challinor,
J.Debreczeni,
K.Eckersley,
G.Fairley,
L.Feron,
V.Flemington,
M.A.Graham,
R.Greenwood,
P.Hopcroft,
T.D.Howard,
M.James,
C.D.Jones,
C.R.Jones,
J.Renshaw,
K.Roberts,
L.Snow,
M.Tonge,
K.Yeung.
Structure-Guided Design of Highly Selective and Potent Covalent Inhibitors of ERK1/2. J.Med.Chem. 2015.
Page generated: Sat Dec 12 11:29:23 2020
ISSN: ESSN 1520-4804 PubMed: 25977981 DOI: 10.1021/ACS.JMEDCHEM.5B00466 |
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