Chlorine in PDB 5a2v: Crystal Structure of Mtpap in Apo Form

The structure of Crystal Structure of Mtpap in Apo Form, PDB code: 5a2v was solved by M.Lapkouski, B.M.Hallberg, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	38.00 / 1.82
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	59.391, 94.367, 191.849, 90.00, 90.00, 90.00
R / Rfree (%)	22.2 / 24.5

The binding sites of Chlorine atom in the Crystal Structure of Mtpap in Apo Form (pdb code 5a2v). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Crystal Structure of Mtpap in Apo Form, PDB code: 5a2v:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the Crystal Structure of Mtpap in Apo Form


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Mtpap in Apo Form within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1528 b:28.1 occ:1.00 O A:HOH2251 3.1 33.5 1.0 OG A:SER331 3.2 28.4 1.0 ND2 A:ASN229 3.4 25.3 1.0 CA A:GLY225 3.7 22.8 1.0 CA A:SER331 3.7 28.2 1.0 CD1 A:LEU334 3.7 26.2 1.0 N A:SER331 3.9 28.7 1.0 CB A:SER331 4.0 28.4 1.0 CE1 A:PHE372 4.0 30.0 1.0 CD1 A:PHE372 4.1 29.6 1.0 C A:CYS330 4.2 28.9 1.0 O A:CYS330 4.3 27.8 1.0 N A:GLY225 4.3 23.1 1.0 C A:GLY225 4.4 22.8 1.0 CG A:ASN229 4.4 25.3 1.0 CB A:ASN229 4.5 25.2 1.0 CB A:CYS330 4.6 30.9 1.0 O A:HOH2178 4.6 33.7 1.0 CG A:LEU334 4.6 25.8 1.0 O A:GLY225 4.8 22.2 1.0 O A:ALA327 4.8 33.4 1.0 CB A:LEU334 4.9 25.6 1.0 C A:SER331 5.0 28.2 1.0

Chlorine binding site 2 out of 4 in the Crystal Structure of Mtpap in Apo Form


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Mtpap in Apo Form within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1528 b:24.1 occ:1.00 O B:HOH2206 3.1 33.8 1.0 OG B:SER331 3.2 23.2 1.0 ND2 B:ASN229 3.3 20.3 1.0 CA B:SER331 3.5 23.1 1.0 N B:SER331 3.7 23.7 1.0 CA B:GLY225 3.7 21.5 1.0 CB B:SER331 3.9 23.3 1.0 CD1 B:LEU334 3.9 21.0 1.0 C B:CYS330 4.0 24.8 1.0 SG B:CYS330 4.1 26.1 0.5 O B:CYS330 4.1 23.3 1.0 N B:GLY225 4.3 21.6 1.0 CG B:ASN229 4.3 20.5 1.0 C B:GLY225 4.4 21.6 1.0 CB B:ASN229 4.4 20.6 1.0 CB B:CYS330 4.4 26.6 0.5 CB B:CYS330 4.4 25.7 0.5 O B:GLY225 4.7 21.6 1.0 CE1 B:PHE372 4.7 29.4 1.0 O B:ALA327 4.8 29.4 1.0 CG B:LEU334 4.8 21.1 1.0 C B:SER331 4.8 22.6 1.0 CA B:CYS330 4.9 25.6 0.5 CA B:CYS330 4.9 25.2 0.5 CB B:LEU334 4.9 20.6 1.0 CD1 B:PHE372 5.0 29.4 1.0

Chlorine binding site 3 out of 4 in the Crystal Structure of Mtpap in Apo Form


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of Mtpap in Apo Form within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1529 b:34.7 occ:1.00 NZ B:LYS233 2.9 25.0 0.5 O B:HOH2216 3.0 22.6 1.0 O B:HOH2234 3.1 45.4 1.0 O B:HOH2118 3.2 33.5 1.0 NE B:ARG356 3.3 32.0 1.0 CA B:CYS353 3.5 23.0 1.0 N B:CYS353 3.6 21.7 1.0 CE B:LYS233 3.7 24.8 0.5 CD B:LYS233 3.7 24.3 0.5 CE B:LYS233 3.7 24.8 0.5 C B:ARG352 3.9 21.6 1.0 CE2 B:TYR191 3.9 24.9 1.0 CD B:LYS233 3.9 24.4 0.5 O B:ARG352 4.0 22.1 1.0 CB B:CYS353 4.0 23.4 1.0 NZ B:LYS233 4.0 25.0 0.5 CB B:ARG352 4.3 21.3 0.5 CB B:ARG352 4.3 21.6 0.5 CD2 B:TYR191 4.4 24.1 1.0 CD B:ARG356 4.5 30.9 1.0 SG B:CYS353 4.7 25.6 1.0 CB B:ARG356 4.7 29.1 1.0 CA B:ARG352 4.8 21.3 0.5 CA B:ARG352 4.8 21.4 0.5 C B:CYS353 4.8 22.8 1.0 O B:HOH2217 4.8 25.2 1.0 O B:PHE349 4.9 16.9 1.0 CZ B:TYR191 5.0 24.9 1.0

Chlorine binding site 4 out of 4 in the Crystal Structure of Mtpap in Apo Form


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of Mtpap in Apo Form within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1530 b:50.4 occ:1.00 O B:HOH2032 3.1 40.6 1.0 O B:HOH2033 3.2 49.4 1.0 N B:LEU144 3.2 36.1 1.0 CB B:THR143 3.6 30.7 1.0 CA B:THR143 3.6 31.1 1.0 CG2 B:THR143 3.9 30.9 1.0 CB B:PRO74 3.9 35.0 1.0 C B:THR143 3.9 32.7 1.0 CG B:LEU144 4.0 39.6 1.0 CB B:LEU144 4.1 39.5 1.0 CA B:PRO74 4.1 35.1 1.0 N B:SER75 4.1 40.2 1.0 CA B:LEU144 4.2 39.2 1.0 CD1 B:LEU144 4.4 40.2 1.0 O B:LEU144 4.5 42.5 1.0 C B:PRO74 4.7 37.4 1.0 CG B:PRO147 4.8 52.3 1.0 CG B:PRO74 4.9 34.5 1.0 C B:LEU144 4.9 41.8 1.0 CB B:PRO147 4.9 52.2 1.0 OG1 B:THR143 4.9 30.3 1.0 O B:PHE142 4.9 27.6 1.0 N B:THR143 5.0 29.7 1.0

M.Lapkouski, B.M.Hallberg. Structure of Mitochondrial Poly(A) Rna Polymerase Reveals the Structural Basis For Dimerization, Atp Selectivity and the SPAX4 Disease Phenotype. Nucleic Acids Res. V. 43 9065 2015.
ISSN: ISSN 0305-1048
PubMed: 26319014
DOI: 10.1093/NAR/GKV861