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Chlorine in PDB 5aep: Novel Pyrrole Carboxamide Inhibitors of JAK2 As Potential Treatment of Myeloproliferative DisordersEnzymatic activity of Novel Pyrrole Carboxamide Inhibitors of JAK2 As Potential Treatment of Myeloproliferative Disorders
All present enzymatic activity of Novel Pyrrole Carboxamide Inhibitors of JAK2 As Potential Treatment of Myeloproliferative Disorders:
2.7.10.2; Protein crystallography data
The structure of Novel Pyrrole Carboxamide Inhibitors of JAK2 As Potential Treatment of Myeloproliferative Disorders, PDB code: 5aep
was solved by
G.Canevari,
J.Bertrand,
M.G.Brasca,
M.Nesi,
N.Amboldi,
N.Avanzi,
S.Bindi,
D.Casero,
M.Ciomei,
N.Colombo,
S.Cribioli,
G.Fachin,
E.R.Felder,
A.Galvani,
A.Isacchi,
I.Motto,
A.Panzeri,
P.Gnocchi,
D.Donati,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Novel Pyrrole Carboxamide Inhibitors of JAK2 As Potential Treatment of Myeloproliferative Disorders
(pdb code 5aep). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Novel Pyrrole Carboxamide Inhibitors of JAK2 As Potential Treatment of Myeloproliferative Disorders, PDB code: 5aep: Chlorine binding site 1 out of 1 in 5aepGo back to Chlorine Binding Sites List in 5aep
Chlorine binding site 1 out
of 1 in the Novel Pyrrole Carboxamide Inhibitors of JAK2 As Potential Treatment of Myeloproliferative Disorders
Mono view Stereo pair view
Reference:
M.G.Brasca,
P.Gnocchi,
M.Nesi,
N.Amboldi,
N.Avanzi,
J.Bertrand,
S.Bindi,
G.Canevari,
D.Casero,
M.Ciomei,
N.Colombo,
S.Cribioli,
G.Fachin,
E.R.Felder,
A.Galvani,
A.Isacchi,
I.Motto,
A.Panzeri,
D.Donati.
Novel Pyrrole Carboxamide Inhibitors of JAK2 As Potential Treatment of Myeloproliferative Disorders. Bioorg.Med.Chem. V. 23 2387 2015.
Page generated: Sat Dec 12 11:30:30 2020
ISSN: ISSN 0968-0896 PubMed: 25882525 DOI: 10.1016/J.BMC.2015.03.059 |
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